Modafinil and Epididymitis - a phase IV clinical study of FDA data


Epididymitis is reported only by a few people who take Modafinil.

The phase IV clinical study analyzes which people take Modafinil and have Epididymitis. It is created by eHealthMe based on reports of 16,746 people who have side effects while taking Modafinil from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 20, 2022

16,746 people reported to have side effects when taking Modafinil.
Among them, 4 people (0.02%) have Epididymitis.

What is Modafinil?

Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 17,547 Modafinil users for its effectiveness, alternative drugs and more.

What is Epididymitis?

Epididymitis (pain in the scrotum or testicle) is found to be associated with 695 drugs and 364 conditions by eHealthMe.

Number of Modafinil and Epididymitis reports submitted per year:

Could Modafinil cause Epididymitis?

Age of people who have Epididymitis when taking Modafinil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 100 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Modafinil *:

  1. Xyrem: 1 person, 25.00%
  2. Tamsulosin Hydrochloride: 1 person, 25.00%
  3. Omeprazole: 1 person, 25.00%
  4. Ibuprofen: 1 person, 25.00%
  5. Flonase Allergy Relief: 1 person, 25.00%
  6. Crestor: 1 person, 25.00%

Common side effects people have besides Epididymitis *:

  1. Testicular Pain (pain in testes): 3 people, 75.00%
  2. Swallowing Difficulty: 1 person, 25.00%
  3. Snoring: 1 person, 25.00%
  4. Obstructive Sleep Apnea Syndrome (a sleep disorder that involves cessation or significant decrease in airflow in the presence of breathing effort): 1 person, 25.00%
  5. Nicotine Dependence: 1 person, 25.00%
  6. Neuropathy Peripheral (surface nerve damage): 1 person, 25.00%
  7. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 1 person, 25.00%
  8. Hoarseness Or Changing Voice: 1 person, 25.00%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 25.00%
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 25.00%

Common conditions people have *:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Modafinil and have Epididymitis?

Check whether Epididymitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Epididymitis and when was it recovered:

Expand to all the drugs that have ingredients of modafinil:

Alternative drugs to, pros and cons of Modafinil:

Common Modafinil side effects:

Browse all side effects of Modafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Epididymitis treatments and more:

COVID vaccines that are related to Epididymitis:

Common drugs associated with Epididymitis:

All the drugs that are associated with Epididymitis:

All the conditions that are associated with Epididymitis:

How the study uses the data?

The study uses data from the FDA. It is based on modafinil (the active ingredients of Modafinil) and Modafinil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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