Modafinil and Myocardial ischaemia - a phase IV clinical study of FDA data
Summary:
Myocardial ischaemia is reported only by a few people who take Modafinil.
The phase IV clinical study analyzes which people take Modafinil and have Myocardial ischaemia. It is created by eHealthMe based on reports of 15,109 people who have side effects while taking Modafinil from the FDA, and is updated regularly.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
15,109 people reported to have side effects when taking Modafinil.
Among them, 2 people (0.01%) have Myocardial ischaemia.
What is Modafinil?
Modafinil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 15,835 Modafinil users for its effectiveness, alternative drugs and more.
What is Myocardial ischaemia?
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased) is found to be associated with 1,622 drugs and 935 conditions by eHealthMe.
Number of Modafinil and Myocardial ischaemia reports submitted per year:

Gender of people who have Myocardial ischaemia when taking Modafinil *:
- female: 50 %
- male: 50 %
Age of people who have Myocardial ischaemia when taking Modafinil *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 100 %
- 50-59: 0.0 %
- 60+: 0.0 %
Common drugs people take besides Modafinil *:
- Vitamin D3: 1 person, 50.00%
- Vitamin B12: 1 person, 50.00%
- Viagra: 1 person, 50.00%
- Plegridy: 1 person, 50.00%
- Gilenya: 1 person, 50.00%
- Flexeril: 1 person, 50.00%
Common side effects people have besides Myocardial ischaemia *:
- Headache (pain in head): 1 person, 50.00%
- Electrocardiogram Abnormal: 1 person, 50.00%
- Dizziness: 1 person, 50.00%
- Cardiac Disorder: 1 person, 50.00%
- Bundle Branch Block Right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 1 person, 50.00%
- Bradycardia (abnormally slow heart action): 1 person, 50.00%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 50.00%
Common conditions people have *:
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 50.00%
* Approximation only. Some reports may have incomplete information.
Do you take Modafinil and have Myocardial ischaemia?
Check whether Myocardial ischaemia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Lopes E, Pereira D, da Silva Behrens NS, de Almeida Fonseca H, Calvancanti PO, de Araújo Lima TF, Pradella-Hallinan M, Castro J, Tufik S, Coelho FM, "Cataplexy as a side effect of modafinil in a patient without narcolepsy", Sleep Science, 2014 Mar .
Related studies
Alternative drugs to, pros and cons of Modafinil:
- Modafinil (15,835 reports)
Myocardial ischaemia treatments and more:
- Myocardial ischaemia (25,523 reports)
COVID vaccines that are related to Myocardial ischaemia:
- Myocardial ischaemia in Moderna COVID Vaccine
- Myocardial ischaemia in Pfizer BioNTech Covid Vaccine
- Myocardial ischaemia in Johnson and Johnson Covid Vaccine
How severe was Myocardial ischaemia and when was it recovered:
Expand to all the drugs that have ingredients of modafinil:
Common drugs associated with Myocardial ischaemia:
- Accupril: 124 reports
- Acetaminophen: 221 reports
- Acetylsalicylic acid: 372 reports
- Actos: 175 reports
- Albuterol: 317 reports
- Aldactone: 136 reports
- Allopurinol: 366 reports
- Alprazolam: 187 reports
- Altace: 195 reports
- Amaryl: 188 reports
- Ambien: 218 reports
- Amlodipine: 428 reports
- Amoxicillin: 103 reports
- Aredia: 106 reports
- Aspirin: 1,569 reports
- Atenolol: 545 reports
- Ativan: 135 reports
- Atorvastatin calcium: 177 reports
- Atrovent: 123 reports
- Avandamet: 614 reports
- Avandaryl: 156 reports
- Avandia: 3,793 reports
- Bactrim: 116 reports
- Bisoprolol fumarate: 101 reports
- Carboplatin: 121 reports
- Cardizem: 169 reports
- Cardura: 107 reports
- Carvedilol: 249 reports
- Celebrex: 341 reports
- Cisplatin: 168 reports
- Clonazepam: 133 reports
- Clonidine: 121 reports
- Clopidogrel: 306 reports
- Clozaril: 236 reports
- Coreg: 211 reports
- Coumadin: 338 reports
- Cozaar: 172 reports
- Crestor: 242 reports
- Cyclophosphamide: 197 reports
- Dexamethasone: 218 reports
- Diazepam: 163 reports
- Digoxin: 494 reports
- Diovan: 302 reports
- Effexor: 163 reports
- Enalapril maleate: 134 reports
- Famotidine: 120 reports
- Fentanyl: 172 reports
- Flomax: 129 reports
- Flonase: 109 reports
- Fluorouracil: 275 reports
- Fluoxetine: 120 reports
- Folic acid: 267 reports
- Fosamax: 347 reports
- Furosemide: 755 reports
- Gabapentin: 186 reports
- Glipizide: 175 reports
- Glucophage: 370 reports
- Glucotrol: 198 reports
- Glyburide: 178 reports
- Heparin: 266 reports
- Humalog: 119 reports
- Humira: 343 reports
- Hydrochlorothiazide: 341 reports
- Ibuprofen: 252 reports
- Imdur: 212 reports
- Insulin: 139 reports
- Isosorbide dinitrate: 109 reports
- Isosorbide mononitrate: 182 reports
- Lactulose: 119 reports
- Lanoxin: 130 reports
- Lansoprazole: 278 reports
- Lantus: 204 reports
- Lasix: 771 reports
- Levaquin: 134 reports
- Levothyroxine sodium: 214 reports
- Lexapro: 112 reports
- Lipitor: 863 reports
- Lisinopril: 666 reports
- Lopressor: 268 reports
- Lopurin: 366 reports
- Loraz: 266 reports
- Lorazepam: 271 reports
- Losartan: 120 reports
- Lovenox: 110 reports
- Lyrica: 104 reports
- Metformin: 800 reports
- Metformin hydrochloride: 103 reports
- Methotrexate: 369 reports
- Metoclopramide: 140 reports
- Metoprolol tartrate: 248 reports
- Morphine: 246 reports
- Neurontin: 238 reports
- Nexium: 266 reports
- Nifedipine: 150 reports
- Nitroglycerin: 425 reports
- Norvasc: 531 reports
- Omeprazole: 452 reports
- Ondansetron: 106 reports
- Oxaliplatin: 129 reports
- Oxycodone: 159 reports
- Oxycontin: 125 reports
- Paclitaxel: 117 reports
- Pantoprazole: 267 reports
- Paracetamol: 104 reports
- Paxil: 147 reports
- Pepcid: 108 reports
- Percocet: 112 reports
- Plavix: 748 reports
- Pravachol: 169 reports
- Prednisolone: 318 reports
- Prednisone: 547 reports
- Premarin: 165 reports
- Prevacid: 284 reports
- Prilosec: 337 reports
- Propofol: 121 reports
- Protonix: 289 reports
- Prozac: 156 reports
- Ramipril: 286 reports
- Ranitidine: 205 reports
- Remicade: 172 reports
- Revlimid: 126 reports
- Rosiglitazone: 411 reports
- Rosiglitazone maleate: 237 reports
- Simvastatin: 570 reports
- Spiriva: 151 reports
- Spironolactone: 247 reports
- Synthroid: 338 reports
- Tasigna: 161 reports
- Temaz: 120 reports
- Temazepam: 119 reports
- Toprol-xl: 342 reports
- Tramadol: 222 reports
- Tricor: 101 reports
- Tylenol: 326 reports
- Ultram: 103 reports
- Valsartan: 113 reports
- Vasotec: 148 reports
- Viagra: 153 reports
- Vicodin: 181 reports
- Vioxx: 1,541 reports
- Vitamins: 122 reports
- Warfarin sodium: 187 reports
- Wellbutrin: 103 reports
- Xanax: 229 reports
- Zantac: 153 reports
- Zestril: 143 reports
- Zetia: 140 reports
- Zocor: 533 reports
- Zofran: 112 reports
- Zoloft: 202 reports
- Zometa: 170 reports
- Zyprexa: 179 reports
- Zyrtec: 126 reports
All the drugs that are associated with Myocardial ischaemia:
- Myocardial ischaemia (1,622 drugs)
Common conditions associated with Myocardial ischaemia:
- Acid reflux: 137 reports
- A-fib: 199 reports
- Antidepressant therapy: 289 reports
- Anxiety: 130 reports
- Arthralgia: 126 reports
- Arthritis: 285 reports
- Arthritis - rheumatoid: 603 reports
- Asthma: 132 reports
- Atrial fibrillation: 203 reports
- Atrial fibrillation/flutter: 199 reports
- Back pain: 136 reports
- Back pain - nonspecific: 136 reports
- Blood cholesterol abnormal: 356 reports
- Blood cholesterol increased: 356 reports
- Blood pressure - high: 834 reports
- Blood pressure increased: 867 reports
- Blood triglycerides increased: 356 reports
- Bone and joint pain: 126 reports
- Breast cancer: 190 reports
- Cancer - breast: 188 reports
- Chronic myeloid leukaemia: 327 reports
- Chronic obstructive pulmonary disease: 123 reports
- Degenerative joint disease: 117 reports
- Depression: 291 reports
- Diabetes: 2,923 reports
- Diabetes mellitus: 2,912 reports
- Diabetes mellitus management: 2,908 reports
- Diabetes mellitus non-insulin-dependent: 459 reports
- Dm: 2,908 reports
- Dyslipidemia: 370 reports
- Gastroesophageal reflux disease: 137 reports
- Hbp: 834 reports
- High blood cholesterol: 370 reports
- High blood pressure: 834 reports
- Hypercholesterolaemia: 356 reports
- Hyperlipidaemia: 120 reports
- Hypertension: 844 reports
- Hypothyroidism: 156 reports
- Joint aches: 126 reports
- Joint pain: 126 reports
- Lipid profile: 270 reports
- Multiple myeloma: 252 reports
- Multiple sclerosis: 162 reports
- Myocardial ischaemia: 105 reports
- Niddm: 561 reports
- Osteoarthritis: 121 reports
- Osteoporosis: 343 reports
- Pain: 351 reports
- Plasma cell myeloma: 252 reports
- Preventive health care: 167 reports
- Psoriasis: 114 reports
- Rheumatoid arthritis: 603 reports
- Schizophrenia: 228 reports
- Sleeping: 106 reports
- Stress: 129 reports
- Stress and anxiety: 129 reports
- Tension: 129 reports
- Type 2 diabetes: 567 reports
- Type 2 diabetes mellitus: 561 reports
All the conditions that are associated with Myocardial ischaemia:
- Myocardial ischaemia (935 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on modafinil (the active ingredients of Modafinil) and Modafinil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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