Mucinex and Nail discoloration - a phase IV clinical study of FDA data


Nail discoloration is found among people who take Mucinex, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Mucinex and have Nail discoloration. It is created by eHealthMe based on reports of 23,781 people who have side effects when taking Mucinex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

23,781 people reported to have side effects when taking Mucinex.
Among them, 12 people (0.05%) have Nail discoloration.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 25,377 Mucinex users for its effectiveness, alternative drugs and more.

What is Nail discoloration?

Nail discoloration is found to be associated with 1,331 drugs and 882 conditions by eHealthMe.

Number of Mucinex and Nail discoloration reports submitted per year:

Could Mucinex cause Nail discoloration?

Gender of people who have Nail discoloration when taking Mucinex *:

  • female: 58.33 %
  • male: 41.67 %

Age of people who have Nail discoloration when taking Mucinex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 0.0 %
  • 60+: 77.78 %

Common drugs people take besides Mucinex *:

  1. Vitamin B12: 5 people, 41.67%
  2. Spiriva: 5 people, 41.67%
  3. Vitamin D3: 3 people, 25.00%
  4. Crestor: 3 people, 25.00%
  5. Singulair: 3 people, 25.00%
  6. Acidophilus: 2 people, 16.67%
  7. Prednisone: 2 people, 16.67%
  8. Flexeril: 2 people, 16.67%
  9. Fish Oil: 2 people, 16.67%
  10. Imbruvica: 2 people, 16.67%

Common side effects people have besides Nail discoloration *:

  1. Fungal Nail Infection: 4 people, 33.33%
  2. Sinusitis (inflammation of sinus): 4 people, 33.33%
  3. Itching: 4 people, 33.33%
  4. Fatigue (feeling of tiredness): 4 people, 33.33%
  5. Nail Disorder (disease of nail): 4 people, 33.33%
  6. Peripheral Swelling: 4 people, 33.33%
  7. Inflammation: 3 people, 25.00%
  8. Rashes (redness): 3 people, 25.00%
  9. Pain In Extremity: 3 people, 25.00%
  10. Oedema (fluid collection in tissue): 2 people, 16.67%

Common conditions people have *:

  1. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 16.67%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 16.67%
  3. Joint Pain: 2 people, 16.67%
  4. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 2 people, 16.67%
  5. Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
  6. Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
  7. Migraine (headache): 1 person, 8.33%
  8. Middle Ear Effusion (fluid in middle ear): 1 person, 8.33%
  9. High Blood Pressure: 1 person, 8.33%
  10. High Blood Cholesterol: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Mucinex and have Nail discoloration?

Check whether Nail discoloration is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Nail discoloration and when was it recovered:

Expand to all the drugs that have ingredients of guaifenesin:

Alternative drugs to, pros and cons of Mucinex:

Common Mucinex side effects:

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Nail discoloration treatments and more:

COVID vaccines that are related to Nail discoloration:

Common drugs associated with Nail discoloration:

All the drugs that are associated with Nail discoloration:

Common conditions associated with Nail discoloration:

All the conditions that are associated with Nail discoloration:

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Mucinex) and Mucinex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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