Nabumetone and Toothaches - a phase IV clinical study of FDA data


We study 8,916 people who have side effects when taking Nabumetone. Toothaches is found, especially among people who are female, 60+ old, also take Zometa and have Multiple myeloma.

The phase IV clinical study analyzes which people take Nabumetone and have Toothaches. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

8,916 people reported to have side effects when taking Nabumetone.
Among them, 55 people (0.62%) have Toothaches.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is used in arthritis. Currently, eHealthMe is studying from 9,345 Nabumetone users.

What is Toothaches?

Toothaches (tooth pain) is found to be associated with 2,337 drugs and 1,580 conditions by eHealthMe. Currently, we are studying 26,697 people who have Toothaches.

Number of Nabumetone and Toothaches reports submitted per year:

Could Nabumetone cause Toothaches?

Gender of people who have Toothaches when taking Nabumetone *:

  • female: 60 %
  • male: 40 %

Age of people who have Toothaches when taking Nabumetone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.04 %
  • 30-39: 8.16 %
  • 40-49: 6.12 %
  • 50-59: 20.41 %
  • 60+: 63.27 %

Common drugs people take besides Nabumetone *:

  1. Zometa: 40 people, 72.73%
  2. Prednisone: 34 people, 61.82%
  3. Famotidine: 33 people, 60.00%
  4. Lasix: 31 people, 56.36%
  5. Triamcinolone: 29 people, 52.73%
  6. Ketoconazole: 28 people, 50.91%
  7. Ambien: 27 people, 49.09%
  8. Aredia: 25 people, 45.45%
  9. Prilosec: 23 people, 41.82%
  10. Celebrex: 21 people, 38.18%

Common side effects people have besides Toothaches *:

  1. Bone Disorder: 41 people, 74.55%
  2. Pain In Jaw: 37 people, 67.27%
  3. Injury: 36 people, 65.45%
  4. Stress And Anxiety: 36 people, 65.45%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 36 people, 65.45%
  6. Intervertebral Disc Degeneration (spinal disc degeneration): 34 people, 61.82%
  7. Atelectasis (partial or complete collapse of the lung): 33 people, 60.00%
  8. Back Pain: 32 people, 58.18%
  9. Osteonecrosis Of Jaw (death of bone of jaw): 30 people, 54.55%
  10. Chest Pain: 28 people, 50.91%

Common conditions people have *:

  1. Multiple Myeloma (cancer of the plasma cells): 24 people, 43.64%
  2. Trismus (reduced opening of the jaws): 16 people, 29.09%
  3. Osteoporosis (bones weak and more likely to break): 5 people, 9.09%
  4. Insomnia (sleeplessness): 4 people, 7.27%
  5. High Blood Pressure: 4 people, 7.27%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 5.45%
  7. Breast Cancer: 3 people, 5.45%
  8. Diabetes: 3 people, 5.45%
  9. High Blood Cholesterol: 3 people, 5.45%
  10. Gastric Disorder (disease of stomach): 2 people, 3.64%

* Approximation only. Some reports may have incomplete information.

Do you take Nabumetone and have Toothaches?

Check whether Toothaches is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Nabumetone side effects by duration, gender and age:

Toothaches treatments and more:

Common drugs associated with Toothaches:

All the drugs that are associated with Toothaches:

Common conditions associated with Toothaches:

All the conditions that are associated with Toothaches:

How the study uses the data?

The study uses data from the FDA. It is based on nabumetone (the active ingredients of Nabumetone) and Nabumetone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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