Naproxen and Collapse - a phase IV clinical study of FDA data


Collapse is found among people who take Naproxen, especially for people who are female, 60+ old, have been taking the drug for 10+ years.

The phase IV clinical study analyzes which people take Naproxen and have Collapse. It is created by eHealthMe based on reports of 54,594 people who have side effects when taking Naproxen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 30, 2022

54,594 people reported to have side effects when taking Naproxen.
Among them, 7 people (0.01%) have Collapse.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 57,574 Naproxen users for its effectiveness, alternative drugs and more.

What is Collapse?

Collapse (sudden functional breakdown) is found to be associated with 801 drugs and 91 conditions by eHealthMe.

Number of Naproxen and Collapse reports submitted per year:

Could Naproxen cause Collapse?

Time on Naproxen when people have Collapse *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

Gender of people who have Collapse when taking Naproxen *:

  • female: 57.14 %
  • male: 42.86 %

Age of people who have Collapse when taking Naproxen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 14.29 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 14.29 %
  • 60+: 42.86 %

Common drugs people take besides Naproxen *:

  1. Mycophenolate Mofetil: 2 people, 28.57%
  2. Zyprexa: 1 person, 14.29%
  3. Claritin: 1 person, 14.29%
  4. Haldol: 1 person, 14.29%
  5. Glyburide: 1 person, 14.29%
  6. Fosamax: 1 person, 14.29%
  7. Enbrel: 1 person, 14.29%
  8. Enalapril Maleate: 1 person, 14.29%
  9. Elavil: 1 person, 14.29%
  10. Droperidol: 1 person, 14.29%

Common side effects people have besides Collapse *:

  1. Joint Pain: 3 people, 42.86%
  2. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 28.57%
  3. Sweating Increased (excess sweating): 2 people, 28.57%
  4. Sudden Death Unexplained: 2 people, 28.57%
  5. Paleness (unusual lightness of skin colour): 2 people, 28.57%
  6. Joint Swelling: 2 people, 28.57%
  7. Cardiac Arrest: 2 people, 28.57%
  8. Productive Cough: 2 people, 28.57%
  9. Weight Decreased: 1 person, 14.29%
  10. Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 1 person, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Naproxen and have Collapse?

Check whether Collapse is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Collapse and when was it recovered:

Expand to all the drugs that have ingredients of naproxen:

Alternative drugs to, pros and cons of Naproxen:

Common Naproxen side effects:

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Collapse treatments and more:

COVID vaccines that are related to Collapse:

Common drugs associated with Collapse:

All the drugs that are associated with Collapse:

All the conditions that are associated with Collapse:

How the study uses the data?

The study uses data from the FDA. It is based on naproxen (the active ingredients of Naproxen) and Naproxen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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