Who have Joint destruction with Naproxen - from FDA reports

Joint destruction is found among people who take Naproxen, especially for people who are female, 10-19 old also take medication Triamcinolone, and have Rheumatoid arthritis. This study is created by eHealthMe based on reports of 48,538 people who have side effects when taking Naproxen from FDA, and is updated regularly.

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On Jan, 11, 2019

48,538 people reported to have side effects when taking Naproxen.
Among them, 20 people (0.04%) have Joint destruction

Number of reports submitted per year:

Could Naproxen cause Joint destruction?

Gender of people who have Joint destruction when taking Naproxen *:

  • female: 94.74 %
  • male: 5.26 %

Age of people who have Joint destruction when taking Naproxen *:

  • 0-1: 0.0 %
  • 2-9: 11.11 %
  • 10-19: 72.22 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 5.56 %
  • 60+: 11.11 %

Top conditions involved for these people *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 18 people, 90.00%
  2. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 2 people, 10.00%
  3. Neuralgia (pain in one or more nerves): 1 person, 5.00%
  4. Menopause (end of monthly cycles in women): 1 person, 5.00%
  5. High Blood Pressure: 1 person, 5.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%
  7. Depression: 1 person, 5.00%

Top co-used drugs for these people *:

  1. Triamcinolone: 9 people, 45.00%
  2. Methotrexate: 5 people, 25.00%
  3. Humira: 4 people, 20.00%
  4. Enbrel: 3 people, 15.00%
  5. Orencia: 2 people, 10.00%
  6. Actemra: 2 people, 10.00%
  7. Duexis: 1 person, 5.00%
  8. Benadryl: 1 person, 5.00%
  9. Metformin: 1 person, 5.00%
  10. Folic Acid: 1 person, 5.00%

Top other side effects for these people *:

  1. Diarrhea: 17 people, 85.00%
  2. Weight Loss: 16 people, 80.00%
  3. Septic Shock (shock due to blood infection): 16 people, 80.00%
  4. Nausea And Vomiting: 16 people, 80.00%
  5. Dizziness: 16 people, 80.00%
  6. Nausea (feeling of having an urge to vomit): 16 people, 80.00%
  7. Body Height Below Normal: 16 people, 80.00%
  8. Drug Ineffective: 16 people, 80.00%
  9. Human Antichimeric Antibody Positive: 16 people, 80.00%
  10. Adrenal Insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 16 people, 80.00%

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

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Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Naproxen
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What would happen?

Predict new side effects and undetected conditions when you take Naproxen and have Joint destruction

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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