Nascobal and Aseptic necrosis - a phase IV clinical study of FDA data


Aseptic necrosis is reported only by a few people who take Nascobal.

The phase IV clinical study analyzes which people take Nascobal and have Aseptic necrosis. It is created by eHealthMe based on reports of 361 people who have side effects while taking Nascobal from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 22, 2022

361 people reported to have side effects when taking Nascobal.
Among them, 2 people (0.55%) have Aseptic necrosis.

What is Nascobal?

Nascobal has active ingredients of cyanocobalamin. eHealthMe is studying from 373 Nascobal users for its effectiveness, alternative drugs and more.

What is Aseptic necrosis?

Aseptic necrosis (the death of bone tissue due to a lack of blood supply) is found to be associated with 2,067 drugs and 1,443 conditions by eHealthMe.

Number of Nascobal and Aseptic necrosis reports submitted per year:

Could Nascobal cause Aseptic necrosis?

Gender of people who have Aseptic necrosis when taking Nascobal *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Aseptic necrosis when taking Nascobal *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 100 %
  • 60+: 0.0 %

Common drugs people take besides Nascobal *:

  1. Zoloft: 2 people, 100.00%
  2. Nuvigil: 2 people, 100.00%
  3. Biktarvy: 2 people, 100.00%
  4. Cozaar: 2 people, 100.00%
  5. Hydroxyzine: 2 people, 100.00%
  6. Kayexalate: 2 people, 100.00%
  7. Lantus: 2 people, 100.00%
  8. Levaquin: 2 people, 100.00%
  9. Lipitor: 2 people, 100.00%
  10. Metformin: 2 people, 100.00%

Common side effects people have besides Aseptic necrosis *:

  1. Tooth Loss: 2 people, 100.00%
  2. Stress And Anxiety: 2 people, 100.00%
  3. Pain: 2 people, 100.00%
  4. Multiple Fractures: 2 people, 100.00%
  5. Emotional Distress: 2 people, 100.00%
  6. Chronic Kidney Disease: 2 people, 100.00%
  7. Bone Loss: 2 people, 100.00%
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 2 people, 100.00%
  9. Acute Kidney Failure: 2 people, 100.00%
  10. Bone Density Decreased: 1 person, 50.00%

Common conditions people have *:

  1. Hiv Infection: 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nascobal and have Aseptic necrosis?

Check whether Aseptic necrosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Nascobal:

Aseptic necrosis treatments and more:

COVID vaccines that are related to Aseptic necrosis:

How severe was Aseptic necrosis and when was it recovered:

Expand to all the drugs that have ingredients of cyanocobalamin:

Common drugs associated with Aseptic necrosis:

All the drugs that are associated with Aseptic necrosis:

Common conditions associated with Aseptic necrosis:

All the conditions that are associated with Aseptic necrosis:

How the study uses the data?

The study uses data from the FDA. It is based on cyanocobalamin (the active ingredients of Nascobal) and Nascobal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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