Navelbine and Hypertensive crisis - a phase IV clinical study of FDA data


Hypertensive crisis is found among people who take Navelbine, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Navelbine and have Hypertensive crisis. It is created by eHealthMe based on reports of 8,352 people who have side effects when taking Navelbine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 26, 2023

8,352 people reported to have side effects when taking Navelbine.
Among them, 9 people (0.11%) have Hypertensive crisis.

What is Navelbine?

Navelbine has active ingredients of vinorelbine tartrate. It is often used in breast cancer. eHealthMe is studying from 8,405 Navelbine users for its effectiveness, alternative drugs and more.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 1,335 drugs and 866 conditions by eHealthMe.

Number of Navelbine and Hypertensive crisis reports submitted per year:

Could Navelbine cause Hypertensive crisis?

Time on Navelbine when people have Hypertensive crisis *:

  • < 1 month: 75 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypertensive crisis when taking Navelbine *:

  • female: 77.78 %
  • male: 22.22 %

Age of people who have Hypertensive crisis when taking Navelbine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Navelbine *:

  1. Herceptin: 6 people, 66.67%
  2. Ramipril: 4 people, 44.44%
  3. Ticlid: 3 people, 33.33%
  4. Rabeprazole Sodium: 3 people, 33.33%
  5. Novorapid: 3 people, 33.33%
  6. Levothyroxine Sodium: 3 people, 33.33%
  7. Levemir: 3 people, 33.33%
  8. Lasix: 3 people, 33.33%
  9. Lanoxin: 3 people, 33.33%
  10. Paraplatin: 2 people, 22.22%

Common side effects people have besides Hypertensive crisis *:

  1. Arrhythmias (irregular heartbeat): 4 people, 44.44%
  2. Chills (felling of cold): 3 people, 33.33%
  3. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2 people, 22.22%
  4. Pulmonary Oedema (fluid accumulation in the lungs): 2 people, 22.22%
  5. Left Ventricular Failure (left ventricle fails to contract forcefully): 2 people, 22.22%
  6. White Blood Cell Count Increased: 1 person, 11.11%
  7. Hepatic Steatosis (fatty liver disease): 1 person, 11.11%
  8. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 11.11%
  9. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 1 person, 11.11%
  10. Drowsiness: 1 person, 11.11%

Common conditions people have *:

  1. Breast Cancer Metastatic: 3 people, 33.33%
  2. Lung Carcinoma Cell Type Unspecified Stage Iv (the lung cancer has spread to other organs of the body, such as the other lung, brain, or liver): 2 people, 22.22%

* Approximation only. Some reports may have incomplete information.

Do you take Navelbine and have Hypertensive crisis?

Check whether Hypertensive crisis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Hypertensive crisis and when was it recovered:

Expand to all the drugs that have ingredients of vinorelbine tartrate:

Alternative drugs to, pros and cons of Navelbine:

Common Navelbine side effects:

Browse all side effects of Navelbine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hypertensive crisis treatments and more:

COVID vaccines that are related to Hypertensive crisis:

Common drugs associated with Hypertensive crisis:

All the drugs that are associated with Hypertensive crisis:

Common conditions associated with Hypertensive crisis:

All the conditions that are associated with Hypertensive crisis:

How the study uses the data?

The study uses data from the FDA. It is based on vinorelbine tartrate (the active ingredients of Navelbine) and Navelbine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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