Neupogen and Peptic ulcer perforation - a phase IV clinical study of FDA data


Peptic ulcer perforation is reported only by a few people who take Neupogen.

The phase IV clinical study analyzes which people take Neupogen and have Peptic ulcer perforation. It is created by eHealthMe based on reports of 22,226 people who have side effects while taking Neupogen from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

22,226 people reported to have side effects when taking Neupogen.
Among them, 2 people (0.01%) have Peptic ulcer perforation.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 22,330 Neupogen users for its effectiveness, alternative drugs and more.

What is Peptic ulcer perforation?

Peptic ulcer perforation is found to be associated with 242 drugs and 112 conditions by eHealthMe.

Number of Neupogen and Peptic ulcer perforation reports submitted per year:

Could Neupogen cause Peptic ulcer perforation?

Gender of people who have Peptic ulcer perforation when taking Neupogen *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Peptic ulcer perforation when taking Neupogen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Neupogen *:

  1. Prednisolone: 2 people, 100.00%
  2. Neoral: 2 people, 100.00%
  3. Methylprednisolone: 2 people, 100.00%
  4. Methotrexate: 2 people, 100.00%
  5. Cellcept: 2 people, 100.00%
  6. Kenalog: 1 person, 50.00%

Common side effects people have besides Peptic ulcer perforation *:

  1. Wound Dehiscence (a surgical incision reopens either internally or externally): 2 people, 100.00%
  2. Haemoglobin Decreased: 2 people, 100.00%
  3. Drug Ineffective: 2 people, 100.00%
  4. Diabetes: 2 people, 100.00%
  5. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 1 person, 50.00%
  6. Cushingoid (obesity and weakening of the muscles): 1 person, 50.00%

Common conditions people have *:

  1. Pyoderma Gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance): 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Neupogen and have Peptic ulcer perforation?

Check whether Peptic ulcer perforation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Neupogen:

Peptic ulcer perforation treatments and more:

COVID vaccines that are related to Peptic ulcer perforation:

How severe was Peptic ulcer perforation and when was it recovered:

Expand to all the drugs that have ingredients of filgrastim:

All the drugs that are associated with Peptic ulcer perforation:

All the conditions that are associated with Peptic ulcer perforation:

How the study uses the data?

The study uses data from the FDA. It is based on filgrastim (the active ingredients of Neupogen) and Neupogen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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