Nexavar and Deep venous thrombosis - a phase IV clinical study of FDA data
Deep venous thrombosis is found among people who take Nexavar, especially for people who are male, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Nexavar and have Deep venous thrombosis. It is created by eHealthMe based on reports of 21,993 people who have side effects when taking Nexavar from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
21,993 people reported to have side effects when taking Nexavar.
Among them, 56 people (0.25%) have Deep venous thrombosis.
What is Nexavar?
Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 22,100 Nexavar users for its effectiveness, alternative drugs and more.
What is Deep venous thrombosis?
Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis) is found to be associated with 3,132 drugs and 2,619 conditions by eHealthMe.
Number of Nexavar and Deep venous thrombosis reports submitted per year:
Time on Nexavar when people have Deep venous thrombosis *:
- < 1 month: 51.85 %
- 1 - 6 months: 40.74 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 3.7 %
- 2 - 5 years: 3.7 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Deep venous thrombosis when taking Nexavar *:
- female: 29.63 %
- male: 70.37 %
Age of people who have Deep venous thrombosis when taking Nexavar *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 1.96 %
- 30-39: 0.0 %
- 40-49: 3.92 %
- 50-59: 23.53 %
- 60+: 68.63 %
Common drugs people take besides Nexavar *:
- Spironolactone: 11 people, 19.64%
- Lactulose: 8 people, 14.29%
- Prevacid: 7 people, 12.50%
- Folic Acid: 7 people, 12.50%
- Inderal La: 7 people, 12.50%
- Torsemide: 7 people, 12.50%
- Imodium: 7 people, 12.50%
- Allopurinol: 7 people, 12.50%
- Lasix: 5 people, 8.93%
- Aspirin: 4 people, 7.14%
Common side effects people have besides Deep venous thrombosis *:
- Pulmonary Embolism (blockage of the main artery of the lung): 12 people, 21.43%
- Rashes (redness): 11 people, 19.64%
- Fatigue (feeling of tiredness): 11 people, 19.64%
- Breathing Difficulty: 10 people, 17.86%
- Oedema Peripheral (superficial swelling): 8 people, 14.29%
- Pain In Extremity: 8 people, 14.29%
- Drowsiness: 8 people, 14.29%
- Renal Failure Acute (rapid kidney dysfunction): 8 people, 14.29%
- Diarrhea: 8 people, 14.29%
- Hyperkalemia (damage to or disease of the kidney): 7 people, 12.50%
Common conditions people have *:
- Hepatic Neoplasm Malignant (liver cancer): 22 people, 39.29%
- High Blood Pressure: 12 people, 21.43%
- Gastric Ulcer (stomach ulcer): 8 people, 14.29%
- Oedema (fluid collection in tissue): 7 people, 12.50%
- Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 7 people, 12.50%
- Anaemia (lack of blood): 7 people, 12.50%
- Diarrhea: 7 people, 12.50%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 7.14%
- Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 4 people, 7.14%
- Nausea (feeling of having an urge to vomit): 3 people, 5.36%
* Approximation only. Some reports may have incomplete information.
Do you take Nexavar and have Deep venous thrombosis?Check whether Deep venous thrombosis is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Alternative drugs to, pros and cons of Nexavar:
- Nexavar (22,100 reports)
Deep venous thrombosis treatments and more:
- Deep venous thrombosis (117,205 reports)
COVID vaccines that are related to Deep venous thrombosis:
- Deep venous thrombosis in Moderna COVID Vaccine
- Deep venous thrombosis in Pfizer BioNTech Covid Vaccine
- Deep venous thrombosis in Johnson and Johnson Covid Vaccine
How severe was Deep venous thrombosis and when was it recovered:
Expand to all the drugs that have ingredients of sorafenib tosylate:
Common drugs associated with Deep venous thrombosis:
All the drugs that are associated with Deep venous thrombosis:
- Deep venous thrombosis (3,132 drugs)
Common conditions associated with Deep venous thrombosis:
All the conditions that are associated with Deep venous thrombosis:
- Deep venous thrombosis (2,619 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on sorafenib tosylate (the active ingredients of Nexavar) and Nexavar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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