Nexium and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is found among people who take Nexium, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months.
The phase IV clinical study analyzes which people take Nexium and have Dupuytren's contracture. It is created by eHealthMe based on reports of 231,329 people who have side effects when taking Nexium from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
231,329 people reported to have side effects when taking Nexium.
Among them, 10 people (0.0%) have Dupuytren's contracture.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 226,517 Nexium users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Nexium and Dupuytren's contracture reports submitted per year:

Time on Nexium when people have Dupuytren's contracture *:
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 100 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Dupuytren's contracture when taking Nexium *:
- female: 80 %
- male: 20 %
Age of people who have Dupuytren's contracture when taking Nexium *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 50 %
- 60+: 50 %
Common drugs people take besides Nexium *:
- Percocet: 4 people, 40.00%
- Methotrexate: 3 people, 30.00%
- Zantac: 3 people, 30.00%
- Humira: 3 people, 30.00%
- Fish Oil: 2 people, 20.00%
- Pataday: 2 people, 20.00%
- Nuvigil: 2 people, 20.00%
- Myrbetriq: 2 people, 20.00%
- Macrobid: 2 people, 20.00%
- Lantus: 2 people, 20.00%
Common side effects people have besides Dupuytren's contracture *:
- Diarrhea: 4 people, 40.00%
- High Blood Pressure: 4 people, 40.00%
- High Blood Cholesterol: 3 people, 30.00%
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 20.00%
- Oedema Peripheral (superficial swelling): 2 people, 20.00%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 20.00%
- Breathing Difficulty: 2 people, 20.00%
- Breathing Sounds - Abnormal (Stridor): 2 people, 20.00%
- Fatigue (feeling of tiredness): 2 people, 20.00%
- Haematochezia (passage of stools containing blood): 2 people, 20.00%
Common conditions people have *:
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 30.00%
- Pain: 3 people, 30.00%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 20.00%
- High Blood Cholesterol: 2 people, 20.00%
- Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 20.00%
- Lipids Increased (excess lipid in body): 1 person, 10.00%
- Indigestion: 1 person, 10.00%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 10.00%
- High Blood Pressure: 1 person, 10.00%
- Depression: 1 person, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of esomeprazole magnesium:
Alternative drugs to, pros and cons of Nexium:
- Nexium (226,517 reports)
Common Nexium side effects:
- Abasia (inability to walk): 578 reports
- Abdominal discomfort: 3,643 reports
- Abdominal distension: 2,160 reports
- Abdominal pain: 4,487 reports
- Abdominal pain lower: 312 reports
- Abdominal pain upper: 5,489 reports
- Abdominal tenderness: 124 reports
- Abnormal behavior: 387 reports
- Abnormal dreams: 444 reports
- Abnormal faeces (abnormal stool): 111 reports
- Abortion spontaneous (naturally occurring miscarriage): 108 reports
- Abscess (pus): 336 reports
- Abscess jaw (tooth abscess or root abscess): 117 reports
- Accident: 204 reports
- Accidental overdose (therapeutic agent): 219 reports
- Accident at work: 121 reports
- Acidosis (build-up of carbon dioxide in the blood): 126 reports
- Acne (skin problems that cause pimples): 333 reports
- Actinic keratosis (skin disease due to sun exposure): 121 reports
- Actinomycosis (infection that causes sores, or abscesses): 107 reports
- Activities of daily living impaired: 612 reports
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 207 reports
- Acute kidney failure: 21,848 reports
- Acute myocardial infarction (acute heart attack): 592 reports
- Acute pulmonary oedema (sudden deposit of fluid in the lung)): 105 reports
- Acute respiratory failure: 362 reports
- Acute upper airway obstruction (blockage occurs in the upper airway): 572 reports
- Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 187 reports
- Adverse drug reaction: 603 reports
- Adverse event: 1,255 reports
- Ageusia (loss of taste functions of the tongue): 322 reports
- Aggression: 381 reports
- Agitation (state of anxiety or nervous excitement): 1,103 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,349 reports
- Alanine aminotransferase increased: 1,010 reports
- Alcoholism (problems with alcohol): 110 reports
- Allergic rhinitis: 313 reports
- Altered state of consciousness (altered state of mind): 262 reports
- Anaemia (lack of blood): 4,489 reports
- Anaemia of chronic disease: 112 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 678 reports
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 142 reports
- Anger: 353 reports
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable): 277 reports
- Angioedema (rapid swelling of the dermis): 275 reports
- Angiopathy (generic term for a disease of the blood vessels): 138 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 847 reports
- Ankle fracture: 607 reports
- Ankylosing spondylitis (type of arthritis affecting the spine): 114 reports
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 484 reports
- Anuria (failure of the kidneys to produce urine): 151 reports
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall): 176 reports
- Aortic arteriosclerosis (hardening of the aortic arteries): 200 reports
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 164 reports
- Aortic valve incompetence: 197 reports
- Apathy: 127 reports
- Aphagia (inability or refusal to swallow): 818 reports
- Aphonia (inability to produce voice): 310 reports
- Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells): 106 reports
- Aplastic anemia: 114 reports
- Appendicitis (inflammation of the appendix): 110 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 3,053 reports
- Appetite disorder (abnormal eating habits): 123 reports
- Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 396 reports
- Application site erythema (redness of the skin at application site): 137 reports
- Application site pruritus (application site severe itching of the skin): 141 reports
- Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 279 reports
- Arrhythmias (irregular heartbeat): 1,709 reports
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked): 289 reports
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery): 266 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 2,542 reports
- Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis): 132 reports
- Arthropathy: 1,226 reports
- Arthropod bite: 122 reports
- Ascites (accumulation of fluid in the abdominal cavity): 540 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 863 reports
- Aspartate aminotransferase increased: 922 reports
- Aspiration: 261 reports
- Asthma: 1,997 reports
- Atelectasis (partial or complete collapse of the lung): 705 reports
- Atherosclerosis (disorder of the arteries): 435 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2,036 reports
- Atrioventricular block (heart block): 102 reports
- Atrioventricular block complete (heart block complete): 121 reports
- Atrioventricular block first degree (heart block first degree): 117 reports
- Azotaemia (excess of urea or other nitrogenous compounds in the blood): 175 reports
- Back disorder: 585 reports
- Back injury: 420 reports
- Back pain: 4,811 reports
- Bacteraemia (presence of bacteria in the blood): 200 reports
- Bacterial infection: 265 reports
- Balance disorder: 1,283 reports
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 742 reports
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 316 reports
- Bedridden: 166 reports
- Belching (release of gas from the digestive tract): 930 reports
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi): 309 reports
- Bipolar disorder (mood disorder): 335 reports
- Bladder cancer: 192 reports
- Bladder disorder: 249 reports
- Bleeding disorders: 280 reports
- Bleeding into the skin: 169 reports
- Blindness: 522 reports
- Blindness unilateral: 193 reports
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 625 reports
- Blockage of leg arteries: 107 reports
- Blood albumin decreased: 180 reports
- Blood alkaline phosphatase increased: 656 reports
- Blood bilirubin increased: 441 reports
- Blood calcium decreased: 339 reports
- Blood calcium increased: 178 reports
- Blood creatine phosphokinase increased: 417 reports
- Blood creatinine increased: 1,069 reports
- Blood disorder: 145 reports
- Blood glucose decreased: 561 reports
- Blood glucose fluctuation: 135 reports
- Blood glucose increased: 1,990 reports
- Blood iron decreased: 255 reports
- Blood lactate dehydrogenase increased: 260 reports
- Blood magnesium decreased: 334 reports
- Blood magnesium increased: 101 reports
- Blood potassium decreased: 703 reports
- Blood pressure diastolic decreased: 155 reports
- Blood pressure fluctuation: 373 reports
- Blood pressure management: 400 reports
- Blood pressure systolic increased: 283 reports
- Blood sodium decreased: 389 reports
- Blood thyroid stimulating hormone increased: 109 reports
- Blood urea increased: 363 reports
- Blood urine present: 297 reports
- Body height decreased: 661 reports
- Body temperature decreased: 224 reports
- Body temperature increased: 218 reports
- Bone cyst: 120 reports
- Bone density decreased: 831 reports
- Bone disorder: 1,825 reports
- Bone erosion: 124 reports
- Bone fragmentation: 132 reports
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 309 reports
- Bone loss: 273 reports
- Bone marrow failure: 280 reports
- Bone pain: 1,369 reports
- Bowel movement irregularity: 143 reports
- Bradycardia (abnormally slow heart action): 630 reports
- Brain neoplasm (tumour of brain): 139 reports
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 146 reports
- Breast cancer: 735 reports
- Breast cancer female: 187 reports
- Breast cancer metastatic: 121 reports
- Breast lump (localized swelling that feels different from the surrounding breast tissue): 159 reports
- Breast pain: 227 reports
- Breathing difficulty: 8,525 reports
- Breathing - slowed or stopped: 279 reports
- Breath odor: 128 reports
- Broken bone: 517 reports
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 104 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2,296 reports
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 174 reports
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 159 reports
- Burning sensation: 1,220 reports
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 499 reports
- Calcium deficiency (lack of calcium): 351 reports
- Cancer - throat or larynx: 138 reports
- Candidiasis (candidiasis or thrush is a fungal infection): 345 reports
- Cardiac arrest: 936 reports
- Cardiac disorder: 1,616 reports
- Cardiac failure: 1,064 reports
- Cardiac failure congestive: 2,099 reports
- Cardiac flutter (abnormal heart rhythm): 135 reports
- Cardiac murmur (an heart sound in valve abnormality): 272 reports
- Cardiac valve disease (heart valve disease): 152 reports
- Cardiogenic shock (inadequate circulation of blood): 135 reports
- Cardiomyopathy (weakening of the heart muscle): 377 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 568 reports
- Carotid artery stenosis (narrowing of carotid artery): 216 reports
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 517 reports
- Cataract (clouding of the lens inside the eye): 1,547 reports
- Celiac disease - sprue (a disease of the small intestine): 195 reports
- Cellulitis (infection under the skin): 1,111 reports
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 130 reports
- Cerebral atrophy (decrement in size of brain): 219 reports
- Cerebral haemorrhage (bleeding within the brain): 423 reports
- Cerebral infarction (less blood supply to brain resulting tissue damage): 399 reports
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand): 152 reports
- Cervical spinal stenosis (narrowing of the spinal canal in the neck): 121 reports
- Cervical vertebral fracture: 101 reports
- Chest pain: 6,762 reports
- Chills (felling of cold): 1,674 reports
- Choking sensation (feeling of obstruction in respiratory system): 141 reports
- Cholangitis (infection of the bile duct): 164 reports
- Cholecystitis (infection of gallbladder): 474 reports
- Cholecystitis acute (rapid infection of gallbladder): 160 reports
- Cholecystitis chronic (long lasting infection of gallbladder): 680 reports
- Choledocholithiasis (stones in the common bile duct): 105 reports
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 346 reports
- Chronic kidney disease: 56,593 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 2,057 reports
- Circulatory collapse: 192 reports
- Clostridial infection (infectious conditions by clostridium bacteria): 112 reports
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 281 reports
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 426 reports
- Colitis (inflammation of colon): 633 reports
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon): 200 reports
- Colon cancer: 300 reports
- Colonic polyp (extra part of colon tissue grow in intestine): 249 reports
- Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 165 reports
- Completed suicide (act of taking one's own life): 137 reports
- Compression fracture (fracture due to pressure caused by injury): 256 reports
- Concussion (short loss of normal brain function in response to a head injury): 206 reports
- Condition: 2,381 reports
- Confusion: 605 reports
- Confusional state: 2,189 reports
- Congestive cardiomyopathy (weakening of heart muscle): 136 reports
- Conjunctivitis (pink eye): 184 reports
- Consciousness - decreased: 505 reports
- Constipation: 3,823 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1,254 reports
- Coronary artery bypass: 139 reports
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 511 reports
- Coronary artery stenosis (narrowing of coronary artery): 172 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 1,311 reports
- Cough: 4,240 reports
- Coughing up blood: 659 reports
- C-reactive protein increased: 508 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 919 reports
- Crying: 472 reports
- Cuts and puncture wounds: 285 reports
- Cyst (a closed sac): 401 reports
- Cytolytic hepatitis (dissolution or destruction of a liver cell): 287 reports
- Cytomegalovirus infection: 135 reports
- Deafness neurosensory: 162 reports
- Deafness unilateral: 101 reports
- Death: 6,186 reports
- Decreased activity: 120 reports
- Decreased interest: 303 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1,440 reports
- Deformity (disfigurement): 541 reports
- Dehydration (dryness resulting from the removal of water): 2,849 reports
- Delirium (wild excitement): 404 reports
- Delusion (a false belief or opinion): 116 reports
- Dementia (madness): 402 reports
- Dementia alzheimer's type (loss of mental ability with alzheimer's symptom): 175 reports
- Dental caries: 647 reports
- Depressed level of consciousness: 341 reports
- Depressed mood: 439 reports
- Depression: 5,135 reports
- Dermal cyst: 132 reports
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 282 reports
- Dermatitis allergic (inflammation of the skin due allergic reaction): 105 reports
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid): 106 reports
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens): 146 reports
- Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 102 reports
- Device dislocation: 106 reports
- Device failure: 191 reports
- Device occlusion: 125 reports
- Device related infection: 255 reports
- Diabetes: 2,461 reports
- Diabetes mellitus inadequate control: 365 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 295 reports
- Diabetic nephropathy (diabetic kidney disease): 378 reports
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus): 267 reports
- Diarrhea: 9,253 reports
- Diarrhea haemorrhagic: 136 reports
- Diastolic dysfunction: 114 reports
- Difficulty in walking: 152 reports
- Diplopia (double vision): 398 reports
- Disability: 387 reports
- Discomfort: 786 reports
- Disease progression: 747 reports
- Disease recurrence: 333 reports
- Disseminated intravascular coagulation (systemic activation of blood coagulation): 281 reports
- Disturbance in attention: 539 reports
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 782 reports
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 723 reports
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine): 301 reports
- Dizziness: 7,168 reports
- Dizziness postural: 111 reports
- Drowsiness: 2,536 reports
- Drug abuse and dependence: 216 reports
- Drug administration error: 316 reports
- Drug dependence: 1,206 reports
- Drug effect decreased: 831 reports
- Drug eruption (adverse drug reaction of the skin): 271 reports
- Drug exposure during pregnancy: 236 reports
- Drug hypersensitivity: 2,023 reports
- Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications): 194 reports
- Drug ineffective: 11,613 reports
- Drug intolerance (drug sensitivity): 728 reports
- Drug level increased: 110 reports
- Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash): 166 reports
- Drug toxicity: 198 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 567 reports
- Dry eyes (lack of adequate tears): 657 reports
- Dry mouth: 1,663 reports
- Dry skin: 678 reports
- Dry throat: 180 reports
- Duodenitis (inflammation of the duodenum): 143 reports
- Dyskinesia (abnormality or impairment of voluntary movement): 498 reports
- Dyslipidaemia (abnormal amount of lipids): 234 reports
- Dyspnea exertional: 727 reports
- Dysstasia (difficulty in standing): 340 reports
- Ear discomfort: 170 reports
- Ear pain: 563 reports
- Eating disorder: 513 reports
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 165 reports
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 375 reports
- Ejection fraction decreased (systolic heart failure): 253 reports
- Electrocardiogram qt prolonged: 405 reports
- Electrolyte imbalance: 206 reports
- Emotional disorder: 363 reports
- Emotional distress: 1,500 reports
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 443 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 321 reports
- Endometrial cancer: 122 reports
- Enlarged heart: 622 reports
- Enlarged prostate: 184 reports
- Enterococcal infection: 111 reports
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 127 reports
- Eosinophil count increased: 108 reports
- Eosinophilia (eosinophil count in the peripheral blood exceeds): 268 reports
- Epigastric discomfort: 230 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 205 reports
- Erection problems: 393 reports
- Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 248 reports
- Erythema multiforme (a type of hypersensitivity reaction): 613 reports
- Escherichia infection (bacterial infection by escherichia coli): 179 reports
- Escherichia urinary tract infection (urinary tract infection by escherichia coli): 113 reports
- Essential hypertension (primary hypertension): 170 reports
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury): 105 reports
- Excoriation (to tear or wear off the skin of): 182 reports
- Exostosis (formation of new bone on the surface of a bone): 570 reports
- Exposed bone in jaw: 186 reports
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 232 reports
- Extrasystoles: 148 reports
- Eye disorder: 399 reports
- Eye haemorrhage (bleeding in the eye): 164 reports
- Eye infection: 135 reports
- Eye irritation: 307 reports
- Eyelid oedema (eyelids are swollen and contain excessive fluid): 179 reports
- Eyelid ptosis (falling of the upper or lower eyelid): 119 reports
- Eye pain: 549 reports
- Eye pruritus (eye itching): 204 reports
- Eye swelling: 356 reports
- Face oedema (swelling of face): 249 reports
- Facial pain: 161 reports
- Faecal incontinence (a lack of control over passing stool): 177 reports
- Faeces discolored: 648 reports
- Failure to thrive (inadequate weight gain and physical growth in children): 142 reports
- Fainting (loss of consciousness and postural tone): 1,469 reports
- Fall: 6,392 reports
- Fatigue (feeling of tiredness): 9,086 reports
- Fear: 392 reports
- Febrile neutropenia (fever with reduced white blood cells): 820 reports
- Feeding disorder (when children refuse to eat certain food groups): 294 reports
- Feeling cold: 303 reports
- Feeling drunk: 123 reports
- Feeling hot: 641 reports
- Feeling jittery: 329 reports
- Femur fracture: 795 reports
- Fever: 4,840 reports
- Fibromyalgia (a long-term condition which causes pain all over the body): 905 reports
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue): 128 reports
- Fibula fracture: 165 reports
- Fistula (an abnormal connection or passageway between two): 227 reports
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 323 reports
- Flatulence (flatus expelled through the anus): 1,590 reports
- Fluid overload (too much fluid in the blood): 268 reports
- Fluid retention (an abnormal accumulation of fluid in the blood): 744 reports
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 103 reports
- Food intolerance (inability to have food): 107 reports
- Foot deformity (functional disability of foot): 267 reports
- Foot fracture: 878 reports
- Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin): 109 reports
- Full blood count decreased: 185 reports
- Fungal infection: 551 reports
- Fungal nail infection: 117 reports
- Furuncle (infection of the hair follicle): 113 reports
- Gait disturbance: 2,676 reports
- Gallbladder disorder: 872 reports
- Gallbladder injury: 148 reports
- Gallbladder operation: 107 reports
- Gallbladder removal: 365 reports
- Gallstones (stone formation by bile component): 1,274 reports
- Gamma-glutamyltransferase increased: 451 reports
- Gangrene (body tissue dies): 125 reports
- Gastric cancer (stomach cancer): 601 reports
- Gastric disorder (disease of stomach): 1,609 reports
- Gastric haemorrhage (bleeding stomach): 257 reports
- Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane): 321 reports
- Gastric ulcer (stomach ulcer): 1,892 reports
- Gastric ulcer haemorrhage (bleeding ulcer of stomach): 206 reports
- Gastritis (inflammation of stomach): 1,366 reports
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection): 222 reports
- Gastroenteritis (inflammation of stomach and intestine): 474 reports
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 352 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10,642 reports
- Gastrointestinal disorder (functional problems of gastrointestinal tract): 1,099 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 1,744 reports
- Gastrointestinal infection (infection of stomach and intestine): 115 reports
- Gastrointestinal inflammation (inflammation of stomach and intestine): 143 reports
- Gastrointestinal pain: 234 reports
- Gastrointestinal perforation (hole in the digestive tract): 210 reports
- Generalised erythema (redness of the skin all over the body): 111 reports
- Generalised oedema (swelling all over the body): 253 reports
- Generalized anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry): 144 reports
- General physical health deterioration (weak health status): 1,548 reports
- Gingival bleeding (bleeding gums): 264 reports
- Gingival disorder (gum disease): 147 reports
- Gingival infection (gum infection): 111 reports
- Gingival pain (gum pain): 281 reports
- Gingivitis (inflammation of gums): 202 reports
- Glaucoma (increased fluid pressure in the eye with vision loss): 513 reports
- Glomerular filtration rate decreased: 130 reports
- Glossodynia (a burning or painful sensation in the tongue): 363 reports
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 219 reports
- Glycosylated haemoglobin increased: 215 reports
- Gout (uric acid crystals building up in the body): 373 reports
- Grand mal convulsion (a type of generalized seizure that affects the entire brain): 199 reports
- Granuloma (a small area of inflammation due to tissue injury): 110 reports
- Groin pain: 240 reports
- Gums - swollen: 181 reports
- Gynecomastia (enlargement of the gland tissue of the male breast): 102 reports
- Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs): 114 reports
- Haematemesis (vomiting of blood): 626 reports
- Haematochezia (passage of stools containing blood): 842 reports
- Haematocrit decreased: 509 reports
- Haematoma (collection of blood outside the blood vessels): 511 reports
- Haematuria (presence of blood in urine): 758 reports
- Haemoglobin decreased: 1,862 reports
- Haemolytic anaemia (anaemia due to haemolysis): 103 reports
- Haemorrhage (bleeding): 1,131 reports
- Haemorrhage intracranial (bleeding within the skull): 116 reports
- Haemorrhagic anaemia (anaemia due to excessive bleeding): 181 reports
- Haemorrhagic diathesis (bleeding tendency): 116 reports
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids): 112 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 893 reports
- Hair color changes: 256 reports
- Hair disorder: 228 reports
- Hair loss: 1,903 reports
- Hallucination, auditory (perceiving sounds without auditory stimulus): 161 reports
- Hallucinations (sensations that appear real but are created by your mind): 787 reports
- Hallucination, visual (seeing things that aren't there): 185 reports
- Hand fracture: 276 reports
- Headache (pain in head): 7,840 reports
- Head discomfort: 176 reports
- Head injury: 2,295 reports
- Hearing impaired: 282 reports
- Hearing loss: 442 reports
- Heart attack: 3,414 reports
- Heart disease: 339 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 1,825 reports
- Heart rate decreased: 480 reports
- Heart rate increased: 1,568 reports
- Heart rate irregular: 621 reports
- Heavy or prolong menstrual bleeding: 132 reports
- Helicobacter infection (helicobacter pylori (h. pylori) infects stomach): 189 reports
- Hemiparesis (weakness on one side of the body): 236 reports
- Hemiplegia (paralysis of one side of the body): 132 reports
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 377 reports
- Hepatic cyst: 203 reports
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 215 reports
- Hepatic enzyme increased: 737 reports
- Hepatic failure (liver failure): 430 reports
- Hepatic lesion: 193 reports
- Hepatic steatosis (fatty liver disease): 547 reports
- Hepatitis (inflammation of the liver): 373 reports
- Hepatitis c: 195 reports
- Hepatitis cholestatic (flow of bile from the liver is slowed or blocked): 134 reports
- Hepatocellular injury (liver injury): 189 reports
- Hepatomegaly (abnormal enlargement of the liver): 275 reports
- Hereditary angioedema (recurrent episodes of severe swelling): 107 reports
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 659 reports
- Herniated nucleus pulposus (slipped disk): 185 reports
- Herpes simplex (herpes simplex is a common viral infection): 115 reports
- Herpes zoster: 928 reports
- Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1,729 reports
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 138 reports
- High blood cholesterol: 2,549 reports
- High blood pressure: 6,891 reports
- Hip fracture: 714 reports
- Hip joint replacement: 219 reports
- Hoarseness or changing voice: 1,354 reports
- Hospitalisation: 619 reports
- Hot flush (sudden feelings of heat): 880 reports
- Humerus fracture (injury to the upper arm bone): 149 reports
- Hyperaesthesia: 163 reports
- Hyperbaric oxygen therapy: 105 reports
- Hyperbilirubinaemia (excess of bilirubin in the blood): 118 reports
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 272 reports
- Hyperchlorhydria (gastric acid levels are higher in stomach): 2,288 reports
- Hyperglycemia (high blood sugar): 573 reports
- Hyperhidrosis (abnormally increased sweating): 1,817 reports
- Hyperkalemia (damage to or disease of the kidney): 1,076 reports
- Hyperkeratosis (thickening of the outer layer of the skin): 166 reports
- Hyperlipidaemia (presence of excess lipids in the blood): 720 reports
- Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 123 reports
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 1,620 reports
- Hypersensitivity: 1,786 reports
- Hypertensive crisis: 117 reports
- Hypertensive nephropathy (hypertensive renal disease): 231 reports
- Hyperthyroidism (over activity of the thyroid gland): 191 reports
- Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate): 104 reports
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 107 reports
- Hyperventilation: 105 reports
- Hypoacusis (loss of hearing): 478 reports
- Hypoaesthesia (reduced sense of touch or sensation): 2,573 reports
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 275 reports
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 167 reports
- Hypocalcaemia (levels of calcium in blood serum are abnormally low): 345 reports
- Hypoglycemia (low blood sugar): 515 reports
- Hypokalemia (low potassium): 1,166 reports
- Hypokinesia (decreased bodily movement): 219 reports
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 289 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 1,016 reports
- Hypophagia (reduced food intake): 607 reports
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 105 reports
- Hypotension (abnormally low blood pressure): 3,364 reports
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 845 reports
- Hypovolaemia (a decreased volume of circulating blood in the body): 211 reports
- Hysterectomy: 153 reports
- Idiopathic pulmonary fibrosis (chronic lung disease): 441 reports
- Ill-defined disorder: 686 reports
- Immune system disorder: 172 reports
- Immunodeficiency: 155 reports
- Impaired driving ability: 180 reports
- Impaired gastric emptying: 379 reports
- Impaired healing: 871 reports
- Impaired work ability: 240 reports
- Inappropriate antidiuretic hormone secretion: 171 reports
- Incontinence (lack of moderation or self-control): 216 reports
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 163 reports
- Increased upper airway secretion: 236 reports
- Indigestion: 6,212 reports
- Infection: 1,645 reports
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus): 113 reports
- Inflammation: 728 reports
- Inflammatory bowel disease: 108 reports
- Influenza like illness: 957 reports
- Infusion related reaction: 623 reports
- Infusion site erythema (reddening of the skin at infusion site): 102 reports
- Ingrowing nail: 118 reports
- Initial insomnia (feeling of inadequate or poor-quality sleep): 130 reports
- Injection site bruising: 456 reports
- Injection site erythema (redness at injection site): 711 reports
- Injection site haematoma (localized swelling filled with blood at injection site): 242 reports
- Injection site haemorrhage (bleeding from injection site): 550 reports
- Injection site mass: 161 reports
- Injection site pain: 1,579 reports
- Injection site pruritus (severe itching at injection site): 371 reports
- Injection site rash: 133 reports
- Injection site reaction: 320 reports
- Injection site swelling: 330 reports
- Injection site urticaria (rash of round, red welts on the skin at injection site): 102 reports
- Injury: 1,926 reports
- Insomnia (sleeplessness): 4,290 reports
- Intentional overdose: 161 reports
- International normalised ratio decreased: 111 reports
- International normalised ratio increased: 587 reports
- Interstitial lung disease: 1,137 reports
- Interstitial nephritis (inflammation of the kidney): 5,749 reports
- Intervertebral disc degeneration (spinal disc degeneration): 922 reports
- Intervertebral disc disorder (spinal disc disorder): 258 reports
- Intervertebral disc protrusion (spinal disc protrusion): 1,059 reports
- Intestinal obstruction: 826 reports
- Intraocular pressure increased: 118 reports
- Iron deficiency: 114 reports
- Iron deficiency anaemia: 417 reports
- Irritability: 621 reports
- Irritable bowel syndrome: 691 reports
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 160 reports
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 168 reports
- Itching: 3,403 reports
- Jaundice - yellow skin (a yellowish pigmentation of the skin): 462 reports
- Jaw disorder (jaw disease): 226 reports
- Jaw fracture: 141 reports
- Joint dislocation (a joint position is changed from normal position): 318 reports
- Joint effusion (presence of extra fluid in joint covering): 211 reports
- Joint injury: 606 reports
- Joint pain: 5,578 reports
- Joint range of motion decreased (disease of joint movement): 294 reports
- Joint stiffness: 337 reports
- Joint swelling: 1,551 reports
- Kidney infection: 442 reports
- Kidney infection (pyelonephritis): 245 reports
- Kidney stones: 1,274 reports
- Knee joint replacement: 317 reports
- Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 178 reports
- Lacrimation increased: 274 reports
- Lactic acidosis (low ph in body tissues): 183 reports
- Large intestine perforation (hole in large intestine): 108 reports
- Laryngitis (inflammation of the larynx): 334 reports
- Left ventricular dysfunction: 155 reports
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 175 reports
- Leukocytosis (increased white blood cells): 367 reports
- Leukopenia (less number of white blood cells in blood): 581 reports
- Libido decreased (loss of interest in sex): 152 reports
- Ligament rupture (tear in ligament): 125 reports
- Ligament sprain (ligament stretched): 268 reports
- Limb discomfort (discomfort in leg): 431 reports
- Limb injury: 523 reports
- Lipase increased: 150 reports
- Lip swelling: 288 reports
- Liver disorder (liver diseases): 759 reports
- Liver injury: 176 reports
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 165 reports
- Localised infection (infection at the single location): 328 reports
- Local swelling (swelling at the site of some application of substance or injury): 432 reports
- Loose tooth: 269 reports
- Loss of consciousness: 1,790 reports
- Low density lipoprotein increased (cholesterol increased in blood): 141 reports
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 180 reports
- Lower limb fracture: 479 reports
- Lower respiratory tract infection: 389 reports
- Low tissue oxygen: 497 reports
- Low turnover osteopathy (slow removal of old bone and its replacement by new bone): 132 reports
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 305 reports
- Lump in the abdomen (an area of swelling or growth on abdomen): 179 reports
- Lung disorder (lung disease): 921 reports
- Lung infection: 354 reports
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 337 reports
- Lung neoplasm (tumour of lung): 325 reports
- Lung neoplasm malignant (cancer tumour of lung): 466 reports
- Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 729 reports
- Lymphocyte count decreased: 204 reports
- Lymphoedema (localized fluid retention and tissue swelling): 173 reports
- Lymphoma (cancer that begins in immune system cells): 253 reports
- Lymphopenia (an abnormally low level of lymphocytes in the blood): 144 reports
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision): 259 reports
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 189 reports
- Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 243 reports
- Malaise (a feeling of general discomfort or uneasiness): 7,988 reports
- Malignant melanoma (skin cancer rises from melancytes): 165 reports
- Malignant neoplasm progression (cancer tumour came back): 1,169 reports
- Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 309 reports
- Mania (a state of abnormally elevated or irritable mood): 176 reports
- Mastication disorder (disease of chewing food): 221 reports
- Maternal exposure during pregnancy (use of substance during pregnancy): 115 reports
- Medical device complication: 103 reports
- Melaena (the passage of black, tarry stools): 414 reports
- Memory loss: 3,037 reports
- Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia): 157 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 677 reports
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 300 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 704 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 445 reports
- Metastases to bone (cancer spreads to bone): 573 reports
- Metastases to central nervous system (cancer spreads to central nervous system): 169 reports
- Metastases to liver (cancer spreads to liver): 380 reports
- Metastases to lung (cancer spreads to lung): 199 reports
- Metastases to lymph nodes (cancer spreads to lymph node): 149 reports
- Metastases to spine (cancer spreads to spine): 195 reports
- Metastatic neoplasm (spreadable cancer tumour): 170 reports
- Micturition urgency (urgency to pass the urine): 261 reports
- Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night): 278 reports
- Migraine (headache): 1,456 reports
- Mitral valve incompetence (inefficient heart valve): 606 reports
- Mitral valve prolapse (heart's mitral valve doesn't work well): 187 reports
- Mobility decreased (ability to move is reduced): 808 reports
- Mood swings (an extreme or rapid change in mood): 472 reports
- Mouth haemorrhage (bleeding from mouth): 116 reports
- Mouth ulcers: 511 reports
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 369 reports
- Movement - uncontrolled or slow: 107 reports
- Movement - uncoordinated: 203 reports
- Mucosal inflammation (infection of mucous membrane): 347 reports
- Multi-organ failure (multisystem organ failure): 402 reports
- Multiple allergies (allergy to multiple agents): 225 reports
- Multiple fractures: 1,166 reports
- Multiple injuries: 283 reports
- Multiple myeloma (cancer of the plasma cells): 595 reports
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 418 reports
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 445 reports
- Muscle aches (muscle pain): 2,495 reports
- Muscle atrophy (a decrease in the mass of the muscle): 189 reports
- Muscle cramps (painful sensations caused by muscle contraction): 138 reports
- Muscle disorder (muscle disease): 168 reports
- Muscle function loss: 166 reports
- Muscle spasms (muscle contraction): 2,873 reports
- Muscle strain (an injury to a muscle in which the muscle fibres tear): 275 reports
- Muscle tightness: 221 reports
- Muscle twitching: 286 reports
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 501 reports
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 570 reports
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 270 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1,407 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 976 reports
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 174 reports
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 266 reports
- Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 142 reports
- Myopathy (a muscular disease in which the muscle fibres do not function): 104 reports
- Myositis (inflammation of the muscles): 176 reports
- Nail disorder (disease of nail): 125 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 938 reports
- Nasal discomfort: 105 reports
- Nasopharyngitis (inflammation of the nasopharynx): 2,243 reports
- Nausea (feeling of having an urge to vomit): 12,063 reports
- Nausea and vomiting: 7,782 reports
- Neck injury: 146 reports
- Neck pain: 1,413 reports
- Neoplasm malignant (cancer tumour): 1,233 reports
- Neoplasm progression (growth of tumour): 241 reports
- Nephrogenic anaemia (anaemia due to kidney disease): 3,404 reports
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 196 reports
- Nephropathy (damage to or disease of a kidney): 1,104 reports
- Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 117 reports
- Nerve compression: 232 reports
- Nerve injury: 273 reports
- Nervousness: 1,044 reports
- Nervous system disorder (a general class of medical conditions affecting the nervous system): 362 reports
- Neuralgia (pain in one or more nerves): 505 reports
- Neuropathy peripheral (surface nerve damage): 1,596 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 466 reports
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 139 reports
- Nightmares (unpleasant dreams): 332 reports
- Night sweats (sweating in night): 521 reports
- Nodule (a small rock or mineral cluster): 211 reports
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system): 119 reports
- Nosebleed (bleeding from nose): 1,018 reports
- Numbness and tingling (unusual prickling sensations): 131 reports
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 132 reports
- Obstructive airways disorder (a progressive disease that makes it hard to breathe): 167 reports
- Ocular hyperaemia (an abnormally large amount of blood in eye): 291 reports
- Oedema (fluid collection in tissue): 977 reports
- Oedema peripheral (superficial swelling): 3,281 reports
- Oesophageal candidiasis (fungal infection of oesophagus): 145 reports
- Oesophageal carcinoma (cancer tumour of oesophagus): 228 reports
- Oesophageal disorder (disease of oesophagus): 483 reports
- Oesophageal pain: 336 reports
- Oesophageal spasm (contraction of oesophagus): 195 reports
- Oesophageal stenosis (narrowing of oesophagus): 172 reports
- Oesophageal ulcer (ulcer of oesophagus): 248 reports
- Oesophagitis (inflammation of oesophagus): 614 reports
- Optic neuritis (optic nerve inflammation): 104 reports
- Oral candidiasis (fungal infection of mouth): 330 reports
- Oral cavity fistula (an abnormal opening in mouth): 111 reports
- Oral discomfort (pain or irritation in mouth): 348 reports
- Oral disorder (mouth disease): 215 reports
- Oral herpes (viral infection of mouth): 193 reports
- Oral infection: 133 reports
- Oral pain: 461 reports
- Oral surgery: 111 reports
- Oropharyngeal pain: 1,550 reports
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 260 reports
- Osteitis (a general term for inflammation of bone): 164 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2,198 reports
- Osteolysis (dissolution of bone): 251 reports
- Osteomyelitis (infection of bone): 971 reports
- Osteonecrosis of jaw (death of bone of jaw): 1,198 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 1,211 reports
- Osteoporosis (bones weak and more likely to break): 2,884 reports
- Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply): 101 reports
- Osteosclerosis (an elevation in bone density): 258 reports
- Otitis (ear infection): 363 reports
- Ovarian cysts (fluid filled sacs of the ovary): 191 reports
- Overdose: 985 reports
- Oxygen saturation decreased: 659 reports
- Pain: 10,638 reports
- Pain in extremity: 4,965 reports
- Pain in jaw: 927 reports
- Pain of skin: 132 reports
- Paleness (unusual lightness of skin colour): 253 reports
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 229 reports
- Pancreatic carcinoma (pancreatic cancer): 222 reports
- Pancreatic disorder: 118 reports
- Pancreatitis (inflammation of pancreas): 1,155 reports
- Pancreatitis acute (sudden inflammation of pancreas): 438 reports
- Pancreatitis chronic (chronic inflammation of pancreas): 137 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 927 reports
- Panic disorder: 820 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2,324 reports
- Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect): 205 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 231 reports
- Parkinson's disease: 334 reports
- Paroxysmal supraventricular tachycardia: 241 reports
- Pathological fracture (broken bone caused by disease): 281 reports
- Pelvic pain: 229 reports
- Pericardial effusion (fluid around the heart): 456 reports
- Pericarditis (inflammation of the pericardium): 121 reports
- Periodontal disease (disease that attacks the gum and bone and around the teeth): 162 reports
- Periodontitis (inflammation of the tissue around the teeth): 226 reports
- Peripheral arterial occlusive disease (reproducible ischemic muscle pain): 174 reports
- Peripheral coldness: 168 reports
- Peripheral ischaemia (impaired circulation to an extremity): 103 reports
- Peripheral swelling: 1,240 reports
- Peripheral vascular disorder: 302 reports
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 218 reports
- Personality change: 112 reports
- Pharyngeal disorder: 103 reports
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 364 reports
- Pharyngitis (inflammation of the pharynx, causing a sore throat): 279 reports
- Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus): 118 reports
- Pharyngolaryngeal pain: 225 reports
- Photophobia (extreme sensitivity to light): 235 reports
- Photosensitivity reaction: 176 reports
- Physical disability: 173 reports
- Plantar fasciitis (painful inflammatory process of the plantar fascia): 127 reports
- Platelet count increased: 213 reports
- Pleural effusion (water on the lungs): 1,473 reports
- Pleural fibrosis (formation of fibrous tissue in lung): 165 reports
- Pleurisy (inflammation of the pleurae, which causes pain when breathing): 158 reports
- Pleuritic pain: 130 reports
- Pneumonia: 5,866 reports
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 500 reports
- Pneumonia bacterial (pneumonia associated with bacterial infection): 174 reports
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 353 reports
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 835 reports
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 165 reports
- Polyp: 351 reports
- Poor quality sleep: 341 reports
- Post procedural complication: 316 reports
- Post procedural haemorrhage (post procedural bleeding): 164 reports
- Post procedural infection: 109 reports
- Post-traumatic stress disorder: 194 reports
- Pre-existing condition improved: 236 reports
- Prescribed overdose: 101 reports
- Pressure ulcer: 233 reports
- Presyncope: 283 reports
- Primary pulmonary hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 205 reports
- Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 297 reports
- Procedural complication: 123 reports
- Procedural pain: 264 reports
- Proctalgia (pain in the rectum): 140 reports
- Productive cough: 789 reports
- Prostate cancer: 287 reports
- Prostatic specific antigen increased: 168 reports
- Prostatomegaly (enlargement of the prostate): 113 reports
- Protein - urine: 434 reports
- Protein urine present: 117 reports
- Pruritus generalised (generalized itching): 388 reports
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 159 reports
- Psoriasis (immune-mediated disease that affects the skin): 648 reports
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 200 reports
- Psychological trauma: 136 reports
- Psychomotor hyperactivity (feelings of extreme restlessness): 145 reports
- Psychotic disorder: 268 reports
- Pulmonary congestion (congestion in the lungs): 309 reports
- Pulmonary embolism (blockage of the main artery of the lung): 1,535 reports
- Pulmonary hypertension (increase in blood pressure in the lung artery): 569 reports
- Pulmonary mass: 249 reports
- Pulmonary oedema (fluid accumulation in the lungs): 679 reports
- Pulmonary thrombosis (scarring in the lungs): 131 reports
- Purpura (purplish discoloration of the skin): 163 reports
- Purulent discharge (discharge that contains pus): 255 reports
- Quality of life decreased: 145 reports
- Quit smoking: 113 reports
- Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 193 reports
- Radius fracture: 120 reports
- Rales (an abnormal respiratory sound characterized by fine crackles): 117 reports
- Rash erythematous (redness of the skin): 417 reports
- Rashes (redness): 5,722 reports
- Rash macular (small, flat red spots): 339 reports
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 373 reports
- Rash papular (redness with papule): 208 reports
- Rash pruritic (redness with itching): 575 reports
- Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas): 106 reports
- Rebound effect (take-back effect): 1,805 reports
- Rectal haemorrhage (bleeding from anus): 925 reports
- Red blood cell count decreased: 483 reports
- Red blood cell sedimentation rate increased: 162 reports
- Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 107 reports
- Regurgitation (expulsion of material): 560 reports
- Renal atrophy (wasting of kidney): 131 reports
- Renal cell carcinoma (a kidney cancer): 310 reports
- Renal cyst (kidney cyst): 643 reports
- Renal disorder (kidney disease): 1,376 reports
- Renal failure acute (rapid kidney dysfunction): 1,617 reports
- Renal failure chronic (long lasting kidney dysfunction): 522 reports
- Renal haemangioma (kidney tumour filled with blood): 1,282 reports
- Renal impairment (severely reduced kidney function): 2,891 reports
- Renal injury (kidney injury): 15,868 reports
- Renal mass (mass in kidney): 124 reports
- Renal pain (kidney pain): 179 reports
- Renal tubular necrosis (death of kidney tubules): 514 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 1,344 reports
- Respiratory disorder (respiratory disease): 383 reports
- Respiratory distress (difficulty in breathing): 456 reports
- Respiratory rate increased (excess breathing rate/min): 124 reports
- Respiratory tract congestion (blockage on respiratory system): 232 reports
- Respiratory tract infection: 332 reports
- Restless leg syndrome (a powerful urge to move your legs): 458 reports
- Retching (strong involuntary effort to vomit): 446 reports
- Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue): 106 reports
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 549 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 1,667 reports
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 213 reports
- Rib fracture: 765 reports
- Rickets (softening of bones): 633 reports
- Right ventricular failure (right half of the heart fails to work): 141 reports
- Road traffic accident: 1,084 reports
- Rosacea (a skin condition that causes facial redness): 102 reports
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 608 reports
- Salivary hypersecretion (excess saliva secretion): 137 reports
- Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 102 reports
- Scab (a hard coating on the skin formed during the wound healing): 135 reports
- Scar: 435 reports
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 314 reports
- Scoliosis (a medical condition in which a person's spine is curved from side to side): 438 reports
- Seasonal allergy (allergic condition due to certain season): 194 reports
- Secretion discharge: 137 reports
- Sedation: 230 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 492 reports
- Sensation of foreign body: 228 reports
- Sensory disturbance (sense disturbance): 209 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 1,717 reports
- Septic shock (shock due to blood infection): 750 reports
- Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 125 reports
- Serum ferritin increased: 103 reports
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 262 reports
- Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 114 reports
- Sick sinus syndrome (a collection of heart rhythm disorders): 101 reports
- Sinus bradycardia (an unusually slow heartbeat due to heart disease): 233 reports
- Sinus congestion (blockage of sinus): 285 reports
- Sinus disorder (disease of sinus): 534 reports
- Sinus headache (headache caused by sinus infections): 145 reports
- Sinusitis (inflammation of sinus): 2,663 reports
- Sinusitis - chronic: 170 reports
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 305 reports
- Sjogren syndrome (a disease that causes dryness in the mouth and eyes): 199 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 1,378 reports
- Skin burning sensation: 243 reports
- Skin cancer: 257 reports
- Skin - clammy: 241 reports
- Skin discoloration: 436 reports
- Skin discoloration - bluish (bluish colour of skin): 203 reports
- Skin disorder (skin disease): 421 reports
- Skin exfoliation (removal of the oldest dead skin cells): 489 reports
- Skin induration (an abnormally hard spot or area on the skin): 110 reports
- Skin infection: 108 reports
- Skin ulcer: 407 reports
- Sleep apnea syndrome: 834 reports
- Sleep disorder: 1,434 reports
- Sleep walking (walking during sleep): 118 reports
- Sluggishness (lacking alertness): 120 reports
- Small intestinal obstruction (blockage in small intestine): 306 reports
- Smell - impaired: 104 reports
- Sneezing: 245 reports
- Speech disorder: 789 reports
- Speech impairment (adult) (inability to speak (adult)): 856 reports
- Spinal column stenosis (narrowing of spinal column): 407 reports
- Spinal compression fracture (fracture due to spinal compression on bone): 416 reports
- Spinal cord compression: 119 reports
- Spinal disorder (disease of spine a back bone): 290 reports
- Spinal fracture (fracture in one of vertebrae): 544 reports
- Spinal fusion surgery: 107 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 932 reports
- Spinal pain (pain in spine): 105 reports
- Splenomegaly (enlargement of spleen): 225 reports
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below): 202 reports
- Sprains (an injury to the ligaments around a joint): 126 reports
- Sputum discolored: 171 reports
- Squamous cell carcinoma (a cancer of a kind of epithelial cell): 162 reports
- Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin): 110 reports
- Stable angina (a constant chest pain): 927 reports
- Staphylococcal bacteraemia (a bacterial infection of blood): 106 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 801 reports
- Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria): 102 reports
- Stent: 180 reports
- Stomach discomfort (pain in abdomen): 210 reports
- Stomatitis (inflammation of mucous membrane of mouth): 840 reports
- Stress and anxiety: 6,744 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2,800 reports
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain): 150 reports
- Subdural haematoma (blood collects between the skull and the surface of the brain): 256 reports
- Suicidal ideation: 872 reports
- Suicide attempt: 389 reports
- Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 167 reports
- Surgery: 684 reports
- Swallowing difficulty: 2,582 reports
- Swallowing pain or burning: 167 reports
- Swelling: 1,343 reports
- Swelling face: 757 reports
- Swollen tongue (swelling of tongue): 406 reports
- Synovial cyst (cyst of joint filled with synovial fluid): 135 reports
- Synovitis (inflammation of the synovial membrane): 102 reports
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 398 reports
- Systemic sclerosis (scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 138 reports
- Tachypnea: 107 reports
- Tardive dyskinesia (a disorder that involves involuntary movements): 254 reports
- Taste - impaired: 1,437 reports
- Temperature intolerance (inability to go in temperature): 128 reports
- Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress): 121 reports
- Tenderness (pain or discomfort when an affected area is touched): 272 reports
- Tendonitis (a condition that causes pain and swelling of tendons): 314 reports
- Tendon rupture (tear of tendon): 194 reports
- The flu (the flu is caused by an influenza virus): 1,500 reports
- Therapeutic agent toxicity (poisoning by ability to cure substance): 171 reports
- Therapeutic response decreased (less preventive response): 412 reports
- Therapeutic response unexpected: 628 reports
- Thermal burn (burn by heat): 105 reports
- Thirst: 235 reports
- Throat irritation: 1,321 reports
- Throat tightness: 445 reports
- Thrombocytopenia (decrease of platelets in blood): 3,040 reports
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 260 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 1,079 reports
- Thyroid cancer: 145 reports
- Thyroid diseases: 454 reports
- Thyroid neoplasm (tumour of thyroid): 129 reports
- Tibia fracture (fracture of lower leg bone): 171 reports
- Tinnitus (a ringing in the ears): 638 reports
- Tongue discoloration: 132 reports
- Tongue disorder (disease of tongue): 152 reports
- Tongue ulceration (ulcers on tongue): 131 reports
- Tooth abscess (pus formation in tooth): 711 reports
- Toothaches (tooth pain): 595 reports
- Tooth disorder (tooth disease): 626 reports
- Tooth extraction: 762 reports
- Tooth fracture: 475 reports
- Tooth loss: 426 reports
- Toxic skin eruption (skin breakdown due to toxic substance): 210 reports
- Transaminases increased: 212 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1,019 reports
- Traumatic injury of the bladder and urethra: 260 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 2,263 reports
- Tricuspid valve incompetence (inefficient heart valve): 467 reports
- Tumor: 422 reports
- Type 1 diabetes: 184 reports
- Type 2 diabetes: 920 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 343 reports
- Ulcer haemorrhage (bleeding ulcer): 317 reports
- Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button): 112 reports
- Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 240 reports
- Unresponsive to stimuli: 301 reports
- Upper-airway cough syndrome: 199 reports
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 272 reports
- Upper limb fracture: 654 reports
- Upper respiratory tract infection: 1,012 reports
- Urinary incontinence (inability to control the flow of urine and involuntary urination): 584 reports
- Urinary retention (the inability to completely or partially empty the bladder): 514 reports
- Urinary tract infection: 3,311 reports
- Urination - excessive at night: 317 reports
- Urination - excessive volume: 180 reports
- Urination - painful: 836 reports
- Urine output decreased: 165 reports
- Urine output - decreased: 122 reports
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 155 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 1,361 reports
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle): 220 reports
- Uveitis (inflammation of the uvea): 103 reports
- Vaginal bleeding: 278 reports
- Varicose vein (veins that have become enlarged and tortuous): 105 reports
- Vasculitis (inflammation of a blood vessel or blood vessels): 196 reports
- Venous thrombosis (blood clot (thrombus) that forms within a vein): 104 reports
- Ventricular extrasystoles (premature cardiac contraction): 301 reports
- Ventricular fibrillation (abnormally irregular heart rhythm): 167 reports
- Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart): 129 reports
- Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do): 117 reports
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 297 reports
- Vertebral foraminal stenosis (narrowing of the intervertebral foramen): 128 reports
- Viral infection: 591 reports
- Vision blurred: 1,716 reports
- Visual acuity reduced (reduced clearness of vision): 586 reports
- Visual disturbance: 125 reports
- Visual field defect: 126 reports
- Visual impairment: 1,208 reports
- Vitamin b12 deficiency: 170 reports
- Vitamin d decreased: 216 reports
- Vitreous floaters (spots before the eyes): 141 reports
- Vocal cord disorder: 123 reports
- Weakness: 7,033 reports
- Weight decreased: 5,246 reports
- Weight fluctuation: 178 reports
- Weight increased: 3,270 reports
- Weight loss: 502 reports
- Wheezing (a high-pitched whistling sound made while you breath): 878 reports
- White blood cell count decreased: 1,259 reports
- White blood cell count increased: 648 reports
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 333 reports
- Wound: 304 reports
- Wound infection: 137 reports
- Wound infection staphylococcal: 135 reports
- Wrist fracture: 470 reports
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium (the active ingredients of Nexium) and Nexium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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