Nicotine and Increased tendency to bruise - a phase IV clinical study of FDA data
Summary:
We study 19,040 people who have side effects when taking Nicotine. Increased tendency to bruise is found, especially among people who are female, 40-49 old, also take Paclitaxel and have Headache.
The phase IV clinical study analyzes which people take Nicotine and have Increased tendency to bruise. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
19,040 people reported to have side effects when taking Nicotine.
Among them, 14 people (0.07%) have Increased tendency to bruise.
What is Nicotine?
Nicotine has active ingredients of nicotine. It is used in quit smoking. Currently, eHealthMe is studying from 19,390 Nicotine users.
What is Increased tendency to bruise?
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone) is found to be associated with 1,424 drugs and 774 conditions by eHealthMe. Currently, we are studying 11,008 people who have Increased tendency to bruise.
Number of Nicotine and Increased tendency to bruise reports submitted per year:

Gender of people who have Increased tendency to bruise when taking Nicotine *:
- female: 85.71 %
- male: 14.29 %
Age of people who have Increased tendency to bruise when taking Nicotine *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 15.38 %
- 40-49: 61.54 %
- 50-59: 7.69 %
- 60+: 15.38 %
Common drugs people take besides Nicotine *:
- Femara: 5 people, 35.71%
- Kytril: 5 people, 35.71%
- Neulasta: 5 people, 35.71%
- Carboplatin: 5 people, 35.71%
- Cimetidine: 5 people, 35.71%
- Methotrexate: 5 people, 35.71%
- Levaquin: 5 people, 35.71%
- Aredia: 5 people, 35.71%
- Aranesp: 5 people, 35.71%
- Paclitaxel: 5 people, 35.71%
Common side effects people have besides Increased tendency to bruise *:
- Pain: 11 people, 78.57%
- Rashes (redness): 8 people, 57.14%
- Nausea (feeling of having an urge to vomit): 7 people, 50.00%
- Thrombocytopenia (decrease of platelets in blood): 7 people, 50.00%
- Dizziness: 7 people, 50.00%
- Pathological Fracture (broken bone caused by disease): 6 people, 42.86%
- Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 42.86%
- Spinal Osteoarthritis (joint cartilage loss in spine): 6 people, 42.86%
- Joint Dislocation (a joint position is changed from normal position): 6 people, 42.86%
- Headache (pain in head): 6 people, 42.86%
Common conditions people have *:
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 28.57%
- Headache (pain in head): 4 people, 28.57%
- Nausea (feeling of having an urge to vomit): 2 people, 14.29%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
- Sleep Disorder: 1 person, 7.14%
- Migraine (headache): 1 person, 7.14%
- Metastases To Bone (cancer spreads to bone): 1 person, 7.14%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
- Depression: 1 person, 7.14%
- Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Nicotine and have Increased tendency to bruise?
Check whether Increased tendency to bruise is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Nicotine side effects by duration, gender and age:
- Nicotine side effects (19,390 reports)
Increased tendency to bruise treatments and more:
- Increased tendency to bruise (11,008 reports)
Common drugs associated with Increased tendency to bruise:
- Aspirin: 1,154 reports
- Enbrel: 1,122 reports
- Prednisone: 935 reports
- Humira: 902 reports
- Fosamax: 713 reports
- Imbruvica: 616 reports
- Methotrexate: 562 reports
- Jakafi: 506 reports
- Vitamin d: 493 reports
- Lisinopril: 436 reports
All the drugs that are associated with Increased tendency to bruise:
- Increased tendency to bruise (1,424 drugs)
Common conditions associated with Increased tendency to bruise:
- Rheumatoid arthritis: 1,415 reports
- Osteoporosis: 656 reports
- Multiple sclerosis: 556 reports
- High blood pressure: 407 reports
- Multiple myeloma: 388 reports
- Psoriasis: 379 reports
All the conditions that are associated with Increased tendency to bruise:
- Increased tendency to bruise (774 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Levothroid and Mycostatin drug interaction - a second ago
- Allegra and Pyridium drug interaction - 2 seconds ago
- Zyprexa and Urine Discoloration - 8 seconds ago
- Cyclophosphamide and Aplastic Anemia - 17 seconds ago
- Zyrtec and Zometa drug interaction - 22 seconds ago
- Amlodipine Besylate and Probiotics drug interaction - 24 seconds ago
- Azithromycin and Ventricular Tachycardia - 25 seconds ago
- Cleocin T and Gastritis - 30 seconds ago
- Amitiza and Cardiac Disorder - 34 seconds ago
- Hydrocortisone and Lichen Planus - 38 seconds ago