Nicotine and Withdrawal syndrome - a phase IV clinical study of FDA data
Summary:
Withdrawal syndrome is found among people who take Nicotine, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Nicotine and have Withdrawal syndrome. It is created by eHealthMe based on reports of 16,518 people who have side effects when taking Nicotine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.
16,518 people reported to have side effects when taking Nicotine.
Among them, 137 people (0.83%) have Withdrawal syndrome.
What is Nicotine?
Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 16,822 Nicotine users for its effectiveness, alternative drugs and more.
What is Withdrawal syndrome?
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance) is found to be associated with 1,656 drugs and 1,312 conditions by eHealthMe.
Number of Nicotine and Withdrawal syndrome reports submitted per year:
Time on Nicotine when people have Withdrawal syndrome *:
Gender of people who have Withdrawal syndrome when taking Nicotine*:
Age of people who have Withdrawal syndrome when taking Nicotine *:
Common drugs people take besides Nicotine *:
Common side effects people have besides Withdrawal syndrome *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Nicotine and have Withdrawal syndrome?
Check whether Withdrawal syndrome is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of Nicotine:
- Nicotine (16,822 reports)
Withdrawal syndrome treatments and more:
- Withdrawal syndrome (35,520 reports)
COVID vaccines that are related to Withdrawal syndrome:
- Withdrawal syndrome in Moderna COVID Vaccine
- Withdrawal syndrome in Pfizer BioNTech Covid Vaccine
- Withdrawal syndrome in Johnson and Johnson Covid Vaccine
How severe was Withdrawal syndrome and when was it recovered:
Expand to all the drugs that have ingredients of nicotine:
Common drugs associated with Withdrawal syndrome:
- Abilify: 348 reports
- Acetaminophen: 101 reports
- Acetylsalicylic acid: 146 reports
- Adderall: 236 reports
- Advil: 120 reports
- Albuterol: 204 reports
- Allegra: 122 reports
- Allopurinol: 110 reports
- Alprazolam: 809 reports
- Ambien: 384 reports
- Amlodipine: 379 reports
- Aripiprazole: 194 reports
- Aspirin: 682 reports
- Atenolol: 327 reports
- Ativan: 339 reports
- Baclofen: 629 reports
- Benadryl: 155 reports
- Buprenorphine: 220 reports
- Buspar: 120 reports
- Butrans: 241 reports
- Calcium: 244 reports
- Cannabis: 104 reports
- Carbamazepine: 135 reports
- Carvedilol: 103 reports
- Celebrex: 317 reports
- Celexa: 224 reports
- Chantix: 499 reports
- Citalopram hydrobromide: 255 reports
- Clonazepam: 1,059 reports
- Clonidine: 344 reports
- Clozapine: 192 reports
- Codeine: 104 reports
- Concerta: 109 reports
- Crestor: 159 reports
- Cymbalta: 1,785 reports
- Darvocet: 102 reports
- Depakote: 171 reports
- Diazepam: 1,013 reports
- Dilaudid: 906 reports
- Duloxetine hydrochloride: 143 reports
- Duragesic: 1,326 reports
- Duragesic-100: 807 reports
- Effexor: 1,354 reports
- Effexor xr: 866 reports
- Escitalopram: 381 reports
- Fentanyl: 601 reports
- Fentanyl-100: 284 reports
- Fentanyl citrate: 203 reports
- Fentanyl transdermal system: 310 reports
- Fish oil: 266 reports
- Flexeril: 213 reports
- Flonase: 146 reports
- Fluoxetine: 546 reports
- Folic acid: 107 reports
- Furosemide: 266 reports
- Gabapentin: 1,159 reports
- Gablofen: 279 reports
- Geodon: 181 reports
- Haldol: 108 reports
- Humira: 124 reports
- Hydrochlorothiazide: 321 reports
- Hydrocodone bitartrate and acetaminophen: 706 reports
- Hydroxyzine: 182 reports
- Hysingla: 121 reports
- Ibu: 619 reports
- Ibuprofen: 619 reports
- Keppra: 111 reports
- Klonopin: 724 reports
- Lamictal: 368 reports
- Lamotrigine: 301 reports
- Lansoprazole: 154 reports
- Lantus: 116 reports
- Lasix: 194 reports
- Latuda: 155 reports
- Levetiracetam: 106 reports
- Levothyroxine sodium: 225 reports
- Lexapro: 390 reports
- Lioresal: 678 reports
- Lipitor: 279 reports
- Lisinopril: 755 reports
- Lithium carbonate: 110 reports
- Lopurin: 110 reports
- Loratadine: 105 reports
- Loraz: 742 reports
- Lorazepam: 742 reports
- Lortab: 201 reports
- Losartan: 254 reports
- Lyrica: 5,805 reports
- Magnesium: 260 reports
- Melatonin: 168 reports
- Meloxicam: 164 reports
- Metformin: 761 reports
- Methotrexate: 213 reports
- Metoprolol tartrate: 110 reports
- Miralax: 109 reports
- Mirtazapine: 576 reports
- Morphine: 856 reports
- Morphine sulfate: 357 reports
- Motrin: 155 reports
- Ms contin: 605 reports
- Multivitamin: 173 reports
- Neurontin: 455 reports
- Nexium: 333 reports
- Nicotine: 137 reports
- Norco: 398 reports
- Norvasc: 116 reports
- Nucynta: 147 reports
- Olanzapine: 285 reports
- Omeprazole: 744 reports
- Opana: 287 reports
- Opana er: 196 reports
- Oxycodone: 776 reports
- Oxycodone and acetaminophen: 106 reports
- Oxycontin: 2,357 reports
- Pantoprazole: 276 reports
- Paracetamol: 271 reports
- Paroxetine: 996 reports
- Paroxetine hydrochloride: 208 reports
- Paxil: 699 reports
- Percocet: 899 reports
- Phenergan: 127 reports
- Plavix: 133 reports
- Potassium: 102 reports
- Prednisolone: 166 reports
- Prednisone: 398 reports
- Pregabalin: 451 reports
- Premarin: 147 reports
- Prevacid: 141 reports
- Prilosec: 297 reports
- Pristiq: 302 reports
- Proair hfa: 126 reports
- Profen: 619 reports
- Protonix: 226 reports
- Prozac: 462 reports
- Quetiapine fumarate: 140 reports
- Ramipril: 127 reports
- Ranitidine: 205 reports
- Risperdal: 216 reports
- Risperidone: 328 reports
- Ritalin: 139 reports
- Roxicodone: 127 reports
- Seroquel: 828 reports
- Seroquel xr: 136 reports
- Sertraline: 960 reports
- Sertraline hydrochloride: 175 reports
- Simvastatin: 453 reports
- Singulair: 202 reports
- Soma: 200 reports
- Suboxone: 373 reports
- Subutex: 191 reports
- Symbicort: 127 reports
- Synthroid: 532 reports
- Temaz: 190 reports
- Temazepam: 187 reports
- Topamax: 199 reports
- Topiramate: 174 reports
- Toprol-xl: 128 reports
- Tramadol: 1,454 reports
- Tramadol hydrochloride: 195 reports
- Tylenol: 269 reports
- Ultram: 187 reports
- Valium: 415 reports
- Valproic acid: 101 reports
- Venlafaxine hydrochloride: 154 reports
- Vicodin: 413 reports
- Vistaril: 120 reports
- Vitamin b12: 252 reports
- Vitamin c: 211 reports
- Vitamin d: 579 reports
- Vitamin d3: 208 reports
- Vitamins: 140 reports
- Vivitrol: 477 reports
- Voltaren: 106 reports
- Vyvanse: 141 reports
- Wellbutrin: 510 reports
- Xanax: 1,086 reports
- Xyrem: 196 reports
- Zanaflex: 127 reports
- Zantac: 124 reports
- Zide: 324 reports
- Zocor: 109 reports
- Zofran: 126 reports
- Zoloft: 634 reports
- Zolpidem: 438 reports
- Zopiclone: 242 reports
- Zyprexa: 241 reports
- Zyrtec: 682 reports
All the drugs that are associated with Withdrawal syndrome:
- Withdrawal syndrome (1,656 drugs)
Common conditions associated with Withdrawal syndrome:
- Acid reflux: 433 reports
- Acupuncture and pain: 2,135 reports
- Add: 389 reports
- Adhd: 389 reports
- Adult hypothyroidism: 286 reports
- Affective disorder: 155 reports
- Agitation: 119 reports
- Alcoholism: 169 reports
- Alcohol problem: 169 reports
- Alcohol use: 169 reports
- Alternative medicine - pain relief: 4,667 reports
- Anticoagulant therapy: 107 reports
- Antidepressant therapy: 4,129 reports
- Anxiety: 2,744 reports
- Anxiety and stress: 2,744 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 2,744 reports
- Anxiety disorder: 359 reports
- Anxiety disorder due to a general medical condition: 359 reports
- Arthralgia: 362 reports
- Arthritis: 401 reports
- Asthma: 301 reports
- Asthma aggravated: 301 reports
- Attention deficit hyperactivity disorder: 389 reports
- Attention deficit/hyperactivity disorder: 145 reports
- Back disorder: 103 reports
- Back pain: 1,464 reports
- Back pain - nonspecific: 1,464 reports
- Bipolar: 708 reports
- Bipolar 1: 102 reports
- Bipolar disorder: 708 reports
- Bipolar i disorder: 102 reports
- Blood cholesterol abnormal: 637 reports
- Blood cholesterol increased: 637 reports
- Blood pressure increased: 1,040 reports
- Blood pressure management: 295 reports
- Blood triglycerides abnormal: 637 reports
- Blood triglycerides increased: 637 reports
- Bone and joint pain: 362 reports
- Bp: 295 reports
- Breakthrough pain: 407 reports
- Cervical spine pain: 205 reports
- Cigarette smoking: 613 reports
- Complex regional pain syndrome: 128 reports
- Constipation: 194 reports
- Crps: 128 reports
- Depression: 4,129 reports
- Depression - major: 442 reports
- Diabetes: 498 reports
- Diabetes mellitus: 498 reports
- Diabetic neuropathy: 393 reports
- Dm: 498 reports
- Drug abuse: 107 reports
- Drug abuser: 107 reports
- Drug dependence: 607 reports
- Dyslipidemia: 637 reports
- Dyssomnia: 712 reports
- Epilepsy: 212 reports
- Fibromyalgia: 2,269 reports
- Fibromyalgia syndrome: 2,269 reports
- Fibrositis: 2,269 reports
- Frequent headaches: 255 reports
- Gad: 359 reports
- Gastric disorder: 114 reports
- Gastroesophageal reflux disease: 433 reports
- Gastrooesophageal reflux disease: 433 reports
- Generalised anxiety disorder: 359 reports
- Generalized anxiety disorder: 359 reports
- Gerd: 433 reports
- Gerds: 433 reports
- Hallucinogen abuse: 115 reports
- Hbp: 1,040 reports
- Headache: 255 reports
- Headaches: 255 reports
- Heartburn: 433 reports
- High blood cholesterol: 637 reports
- High blood cholesterol and triglycerides: 637 reports
- High blood pressure: 1,040 reports
- High cholesterol: 637 reports
- Hormone replacement therapy: 118 reports
- Htn: 1,040 reports
- Hypercholesterolaemia: 637 reports
- Hyperlipidemia: 637 reports
- Hypersensitivity: 257 reports
- Hypertension: 1,040 reports
- Hypothyroid: 286 reports
- Hypothyroidism: 286 reports
- Inability to sleep: 712 reports
- Indigestion: 125 reports
- Insomnia: 712 reports
- Insomnolence: 712 reports
- Intervertebral disc degeneration: 168 reports
- Intervertebral disc protrusion: 133 reports
- Jitters: 2,744 reports
- Joint pain: 362 reports
- Low thyroid: 286 reports
- Major depression: 442 reports
- Major depressive disorder: 442 reports
- Mental disorder: 150 reports
- Migraine: 472 reports
- Ms: 304 reports
- Multiple allergies: 162 reports
- Multiple sclerosis: 304 reports
- Multiple sclerosis aggravated: 304 reports
- Muscle aches: 133 reports
- Muscle relaxant therapy: 161 reports
- Muscle spasms: 399 reports
- Muscle spasticity: 906 reports
- Myofascial pain syndrome: 2,269 reports
- Narcolepsy: 170 reports
- Nausea: 199 reports
- Neck pain: 205 reports
- Neck stiffness: 205 reports
- Nerve injury: 362 reports
- Nerve pain: 1,242 reports
- Neuralgia: 1,242 reports
- Neuropathy peripheral: 1,156 reports
- Niddm: 148 reports
- Obsessive-compulsive disorder: 141 reports
- Osteoarthritis: 172 reports
- Osteoporosis: 139 reports
- Pain: 4,667 reports
- Pain exacerbated: 4,667 reports
- Pain in extremity: 304 reports
- Pain - joints: 362 reports
- Pain management: 4,667 reports
- Pain - neck: 205 reports
- Pain relief: 4,667 reports
- Panic attack: 579 reports
- Panic attacks: 579 reports
- Panic disorder: 579 reports
- Parkinson's disease: 218 reports
- Parkinson's disease aggravated: 218 reports
- Periodic limb movement disorder: 288 reports
- Plmd: 288 reports
- Polyneuropathy: 138 reports
- Postherpetic neuralgia: 1,242 reports
- Post traumatic stress disorder: 260 reports
- Post-traumatic stress disorder: 248 reports
- Quit smoking: 613 reports
- Restless legs syndrome: 288 reports
- Restless leg syndrome: 288 reports
- Rheumatoid arthritis: 282 reports
- Schizophrenia: 324 reports
- Sciatica: 157 reports
- Seasonal allergy: 183 reports
- Sleep aid: 712 reports
- Sleep disorder: 800 reports
- Sleep disorder due to a general medical condition: 800 reports
- Sleep disorder due to general medical condition, insomnia type: 800 reports
- Sleep disorder therapy: 800 reports
- Sleeplessness: 712 reports
- Smoking cessation therapy: 613 reports
- Stiffness in a joint: 362 reports
- Stop smoking: 613 reports
- Stress: 2,744 reports
- Stress and anxiety: 2,744 reports
- Tension: 2,744 reports
- Thyroid diseases: 284 reports
- Thyroid disorder: 284 reports
- Thyroide: 284 reports
- Tobacco abuse: 613 reports
- Tobacco user: 613 reports
- Trigeminal neuralgia: 107 reports
- Type 2 diabetes: 148 reports
- Unipolar depression: 442 reports
All the conditions that are associated with Withdrawal syndrome:
- Withdrawal syndrome (1,312 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on nicotine (the active ingredients of Nicotine) and Nicotine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Armodafinil and Pain In Jaw - 11 seconds ago
- Prezista and Enanthema - 13 seconds ago
- Weight Decreased and Withdrawal Syndrome - 14 seconds ago
- Urecholine and Xalkori drug interaction - 14 seconds ago
- Cimzia and K-Tab drug interaction - 17 seconds ago