Nitro-dur and Muscle twitching - a phase IV clinical study of FDA data

Summary:

We study 2,348 people who have side effects when taking Nitro-dur. Muscle twitching is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Plavix and have Cataplexy.

The phase IV clinical study analyzes which people take Nitro-dur and have Muscle twitching. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 19, 2023

2,348 people reported to have side effects when taking Nitro-dur.
Among them, 5 people (0.21%) have Muscle twitching.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. Currently, eHealthMe is studying from 2,378 Nitro-dur users.

What is Muscle twitching?

Muscle twitching is found to be associated with 2,617 drugs and 1,865 conditions by eHealthMe. Currently, we are studying 27,760 people who have Muscle twitching.

Number of Nitro-dur and Muscle twitching reports submitted per year:

Time on Nitro-dur when people have Muscle twitching *:

Gender of people who have Muscle twitching when taking Nitro-dur *:

female: 60 %
male: 40 %

Age of people who have Muscle twitching when taking Nitro-dur *:

Common drugs people take besides Nitro-dur *:

Lasix: 2 people, 40.00%
Plavix: 2 people, 40.00%
Lansoprazole: 1 person, 20.00%
Januvia: 1 person, 20.00%
Isosorbide Mononitrate: 1 person, 20.00%
Irbesartan: 1 person, 20.00%
Incruse Ellipta: 1 person, 20.00%
Imdur: 1 person, 20.00%
Hydrocodone Bitartrate And Acetaminophen: 1 person, 20.00%
Glimepiride: 1 person, 20.00%

Common side effects people have besides Muscle twitching *:

Fall: 2 people, 40.00%
White Blood Cell Count Decreased: 1 person, 20.00%
Gallstones (stone formation by bile component): 1 person, 20.00%
Electrocardiogram Qt Prolonged: 1 person, 20.00%
Emotional Disorder: 1 person, 20.00%
Exostosis (formation of new bone on the surface of a bone): 1 person, 20.00%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 20.00%
Gait Disturbance: 1 person, 20.00%
Gastritis (inflammation of stomach): 1 person, 20.00%
Heart Rate Increased: 1 person, 20.00%

Common conditions people have *:

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 20.00%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 20.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 20.00%
Impaired Gastric Emptying: 1 person, 20.00%
Femur Fracture: 1 person, 20.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nitro-dur and have Muscle twitching?

Check whether Muscle twitching is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Nitro-dur side effects by duration, gender and age:

Nitro-dur side effects (2,378 reports)

Muscle twitching treatments and more:

Muscle twitching (27,760 reports)

Common drugs associated with Muscle twitching:

All the drugs that are associated with Muscle twitching:

Muscle twitching (2,617 drugs)

Common conditions associated with Muscle twitching:

Depression: 1,719 reports
Multiple sclerosis: 1,403 reports
Pain: 975 reports
Stress and anxiety: 926 reports

All the conditions that are associated with Muscle twitching:

Muscle twitching (1,865 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin (the active ingredients of Nitro-dur) and Nitro-dur (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.