Norco and Pseudotumor cerebri - a phase IV clinical study of FDA data


We study 70,042 people who have side effects when taking Norco. Pseudotumor cerebri is found, especially among people who are female, 30-39 old, also take Mirena and have Birth control.

The phase IV clinical study analyzes which people take Norco and have Pseudotumor cerebri. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

70,042 people reported to have side effects when taking Norco.
Among them, 16 people (0.02%) have Pseudotumor cerebri.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain. Currently, eHealthMe is studying from 72,465 Norco users.

What is Pseudotumor cerebri?

Pseudotumor cerebri (increased pressure within the brain in the absence of a tumour) is found to be associated with 924 drugs and 894 conditions by eHealthMe. Currently, we are studying 5,172 people who have Pseudotumor cerebri.

Number of Norco and Pseudotumor cerebri reports submitted per year:

Could Norco cause Pseudotumor cerebri?

Gender of people who have Pseudotumor cerebri when taking Norco *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Pseudotumor cerebri when taking Norco *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 27.27 %
  • 30-39: 54.55 %
  • 40-49: 18.18 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Norco *:

  1. Mirena: 6 people, 37.50%
  2. Zofran: 4 people, 25.00%
  3. Imuran: 4 people, 25.00%
  4. Ms Contin: 4 people, 25.00%
  5. Robaxin: 4 people, 25.00%
  6. Celexa: 3 people, 18.75%
  7. Dilaudid: 3 people, 18.75%
  8. Keppra: 3 people, 18.75%
  9. Plaquenil: 3 people, 18.75%
  10. Prozac: 3 people, 18.75%

Common side effects people have besides Pseudotumor cerebri *:

  1. Vision Blurred: 10 people, 62.50%
  2. Migraine (headache): 8 people, 50.00%
  3. Headache (pain in head): 7 people, 43.75%
  4. Nausea (feeling of having an urge to vomit): 4 people, 25.00%
  5. High Blood Pressure: 4 people, 25.00%
  6. Visual Impairment: 4 people, 25.00%
  7. Dizziness: 4 people, 25.00%
  8. Injury: 3 people, 18.75%
  9. Blindness Unilateral: 3 people, 18.75%
  10. Tinnitus (a ringing in the ears): 2 people, 12.50%

Common conditions people have *:

  1. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 4 people, 25.00%
  2. Birth Control: 4 people, 25.00%
  3. High Blood Pressure: 3 people, 18.75%
  4. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 12.50%
  5. Joint Pain: 2 people, 12.50%
  6. Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below): 2 people, 12.50%
  7. Asthma: 2 people, 12.50%
  8. Abdominal Pain: 2 people, 12.50%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  10. Nausea And Vomiting: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Norco and have Pseudotumor cerebri?

Check whether Pseudotumor cerebri is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Norco side effects by duration, gender and age:

Pseudotumor cerebri treatments and more:

Common drugs associated with Pseudotumor cerebri:

All the drugs that are associated with Pseudotumor cerebri:

Common conditions associated with Pseudotumor cerebri:

All the conditions that are associated with Pseudotumor cerebri:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Norco) and Norco (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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