Norvasc and Hypertrophic cardiomyopathy - a phase IV clinical study of FDA data

Summary:

Hypertrophic cardiomyopathy is found among people who take Norvasc, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Norvasc and have Hypertrophic cardiomyopathy. It is created by eHealthMe based on reports of 128,409 people who have side effects when taking Norvasc from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Jan, 13, 2023

128,409 people reported to have side effects when taking Norvasc.
Among them, 19 people (0.01%) have Hypertrophic cardiomyopathy.


What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 131,573 Norvasc users for its effectiveness, alternative drugs and more.

What is Hypertrophic cardiomyopathy?

Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick) is found to be associated with 987 drugs and 806 conditions by eHealthMe.

Number of Norvasc and Hypertrophic cardiomyopathy reports submitted per year:

Could Norvasc cause Hypertrophic cardiomyopathy?

Gender of people who have Hypertrophic cardiomyopathy when taking Norvasc *:

  • female: 72.22 %
  • male: 27.78 %

Age of people who have Hypertrophic cardiomyopathy when taking Norvasc *:

  • 0-1: 6.25 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 31.25 %
  • 60+: 50.0 %

Common drugs people take besides Norvasc *:

  1. Prevacid: 4 people, 21.05%
  2. Vioxx: 4 people, 21.05%
  3. Risedronate Sodium: 3 people, 15.79%
  4. Zocor: 3 people, 15.79%
  5. Iressa: 3 people, 15.79%
  6. Soma: 2 people, 10.53%
  7. Cartia Xt: 2 people, 10.53%
  8. Rocaltrol: 2 people, 10.53%
  9. Clarinex: 2 people, 10.53%
  10. Benadryl: 2 people, 10.53%

Common side effects people have besides Hypertrophic cardiomyopathy *:

  1. Fatigue (feeling of tiredness): 4 people, 21.05%
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 15.79%
  3. Hypotension (abnormally low blood pressure): 3 people, 15.79%
  4. Pulmonary Oedema (fluid accumulation in the lungs): 3 people, 15.79%
  5. Headache (pain in head): 3 people, 15.79%
  6. Chest Pain: 3 people, 15.79%
  7. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 15.79%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.79%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 15.79%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 15.79%

Common conditions people have *:

  1. Osteoporosis (bones weak and more likely to break): 4 people, 21.05%
  2. Thyroid Diseases: 1 person, 5.26%
  3. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 5.26%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.26%
  5. Quit Smoking: 1 person, 5.26%
  6. Pain: 1 person, 5.26%
  7. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 1 person, 5.26%
  8. High Blood Cholesterol: 1 person, 5.26%
  9. Heart Disease: 1 person, 5.26%
  10. Gouty Arthritis (joint inflammation with crystal formation): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and have Hypertrophic cardiomyopathy?

Check whether Hypertrophic cardiomyopathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

How severe was Hypertrophic cardiomyopathy and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Alternative drugs to, pros and cons of Norvasc:

Common Norvasc side effects:

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hypertrophic cardiomyopathy treatments and more:

COVID vaccines that are related to Hypertrophic cardiomyopathy:

Common drugs associated with Hypertrophic cardiomyopathy:

All the drugs that are associated with Hypertrophic cardiomyopathy:

Common conditions associated with Hypertrophic cardiomyopathy:

All the conditions that are associated with Hypertrophic cardiomyopathy:

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: