Novalgin and Encephalopathy - a phase IV clinical study of FDA data

Summary:

Encephalopathy is found among people who take Novalgin, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Novalgin and have Encephalopathy. It is created by eHealthMe based on reports of 8,626 people who have side effects when taking Novalgin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 26, 2023

8,626 people reported to have side effects when taking Novalgin.
Among them, 57 people (0.66%) have Encephalopathy.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 8,699 Novalgin users for its effectiveness, alternative drugs and more.

What is Encephalopathy?

Encephalopathy (functioning of the brain is affected by some agent or condition) is found to be associated with 2,067 drugs and 1,586 conditions by eHealthMe.

Number of Novalgin and Encephalopathy reports submitted per year:

Time on Novalgin when people have Encephalopathy *:

Gender of people who have Encephalopathy when taking Novalgin *:

female: 89.29 %
male: 10.71 %

Age of people who have Encephalopathy when taking Novalgin *:

Common drugs people take besides Novalgin *:

Common side effects people have besides Encephalopathy *:

Delirium (wild excitement): 40 people, 70.18%
General Physical Health Deterioration (weak health status): 37 people, 64.91%
Nausea (feeling of having an urge to vomit): 36 people, 63.16%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 36 people, 63.16%
Confusional State: 35 people, 61.40%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 35 people, 61.40%
Hypokalemia (low potassium): 35 people, 61.40%
Head Discomfort: 35 people, 61.40%
Dizziness: 35 people, 61.40%
Urinary Retention (the inability to completely or partially empty the bladder): 35 people, 61.40%

Common conditions people have *:

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 40 people, 70.18%
High Blood Pressure: 40 people, 70.18%
Constipation: 38 people, 66.67%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 36 people, 63.16%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 35 people, 61.40%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 31 people, 54.39%
Calcium Deficiency (lack of calcium): 29 people, 50.88%
Nausea (feeling of having an urge to vomit): 28 people, 49.12%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 10.53%
Insomnia (sleeplessness): 6 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Novalgin and have Encephalopathy?

Check whether Encephalopathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Kapoor A, Kumar V, Beniwal S, Dutta S, Goyal S, Kumar HS, "Posterior reversible encephalopathy syndrome in non-Hodgkin's lymphoma: Not necessarily reversible!", Clinical Cancer Investigation Journal, 2015 Mar .

Related studies

How severe was Encephalopathy and when was it recovered:

Encephalopathy in Novalgin

Expand to all the drugs that have ingredients of metamizole:

Encephalopathy and drugs with ingredients of metamizole

Alternative drugs to, pros and cons of Novalgin:

Novalgin (8,699 reports)

Common Novalgin side effects:

Breathing difficulty: 626 reports
Diarrhea: 597 reports
Fever: 571 reports
Pneumonia: 558 reports
Dizziness: 537 reports
Nausea and vomiting: 533 reports
Fatigue (feeling of tiredness): 500 reports

Browse all side effects of Novalgin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Encephalopathy treatments and more:

Encephalopathy (24,367 reports)

COVID vaccines that are related to Encephalopathy:

Common drugs associated with Encephalopathy:

All the drugs that are associated with Encephalopathy:

Encephalopathy (2,067 drugs)

Common conditions associated with Encephalopathy:

All the conditions that are associated with Encephalopathy:

Encephalopathy (1,586 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metamizole (the active ingredients of Novalgin) and Novalgin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.