Nuplazid and Dementia - a phase IV clinical study of FDA data
Summary:
We study 41,162 people who have side effects when taking Nuplazid. Dementia is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Seroquel and have Parkinson's disease.
The phase IV clinical study analyzes which people take Nuplazid and have Dementia. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
41,162 people reported to have side effects when taking Nuplazid.
Among them, 835 people (2.03%) have Dementia.
What is Nuplazid?
Nuplazid has active ingredients of pimavanserin tartrate. Currently, eHealthMe is studying from 41,167 Nuplazid users.
What is Dementia?
Dementia (madness) is found to be associated with 2,286 drugs and 1,749 conditions by eHealthMe. Currently, we are studying 41,471 people who have Dementia.
Number of Nuplazid and Dementia reports submitted per year:

Time on Nuplazid when people have Dementia *:
Gender of people who have Dementia when taking Nuplazid*:
Age of people who have Dementia when taking Nuplazid *:
Common drugs people take besides Nuplazid *:
Common side effects people have besides Dementia *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Nuplazid and have Dementia?
Check whether Dementia is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Nuplazid side effects by duration, gender and age:
- Nuplazid side effects (41,167 reports)
Dementia treatments and more:
- Dementia (41,471 reports)
Common drugs associated with Dementia:
- Aspirin: 1,644 reports
- Apixaban: 887 reports
- Nuplazid: 835 reports
- Omeprazole: 799 reports
- Revlimid: 798 reports
- Furosemide: 748 reports
- Seroquel: 743 reports
- Eliquis: 707 reports
- Metformin: 700 reports
- Aricept: 692 reports
All the drugs that are associated with Dementia:
- Dementia (2,286 drugs)
Common conditions associated with Dementia:
- Parkinson's disease: 1,737 reports
- Rheumatoid arthritis: 1,220 reports
- High blood pressure: 1,056 reports
- Multiple myeloma: 978 reports
- Multiple sclerosis: 966 reports
All the conditions that are associated with Dementia:
- Dementia (1,749 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pimavanserin tartrate (the active ingredients of Nuplazid) and Nuplazid (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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