Omeprazole and Knee deformity - a phase IV clinical study of FDA data


Knee deformity is found among people who take Omeprazole, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Omeprazole and have Knee deformity. It is created by eHealthMe based on reports of 351,142 people who have side effects when taking Omeprazole from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 03, 2023

351,142 people reported to have side effects when taking Omeprazole.
Among them, 47 people (0.01%) have Knee deformity.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 360,065 Omeprazole users for its effectiveness, alternative drugs and more.

What is Knee deformity?

Knee deformity (functional disability of knee) is found to be associated with 206 drugs and 107 conditions by eHealthMe.

Number of Omeprazole and Knee deformity reports submitted per year:

Could Omeprazole cause Knee deformity?

Gender of people who have Knee deformity when taking Omeprazole *:

  • female: 89.13 %
  • male: 10.87 %

Age of people who have Knee deformity when taking Omeprazole *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.52 %
  • 40-49: 4.76 %
  • 50-59: 38.1 %
  • 60+: 47.62 %

Common drugs people take besides Omeprazole *:

  1. Humira: 19 people, 40.43%
  2. Methotrexate: 8 people, 17.02%
  3. Arava: 7 people, 14.89%
  4. Synthroid: 6 people, 12.77%
  5. Calcium: 5 people, 10.64%
  6. Actemra: 5 people, 10.64%
  7. Paracetamol: 4 people, 8.51%
  8. Folic Acid: 4 people, 8.51%
  9. Fluoxetine: 4 people, 8.51%
  10. Simvastatin: 3 people, 6.38%

Common side effects people have besides Knee deformity *:

  1. Joint Pain: 20 people, 42.55%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 14 people, 29.79%
  3. Joint Swelling: 11 people, 23.40%
  4. Pain In Extremity: 11 people, 23.40%
  5. Gait Disturbance: 9 people, 19.15%
  6. Pain: 9 people, 19.15%
  7. Foot Deformity (functional disability of foot): 8 people, 17.02%
  8. Weakness: 7 people, 14.89%
  9. High Blood Cholesterol: 6 people, 12.77%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.77%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 25 people, 53.19%
  2. Pain: 18 people, 38.30%
  3. High Blood Pressure: 18 people, 38.30%
  4. Gastric Disorder (disease of stomach): 14 people, 29.79%
  5. Depression: 10 people, 21.28%
  6. High Blood Cholesterol: 10 people, 21.28%
  7. Bone Disorder: 9 people, 19.15%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 17.02%
  9. Osteoporosis (bones weak and more likely to break): 7 people, 14.89%
  10. Joint Pain: 6 people, 12.77%

* Approximation only. Some reports may have incomplete information.

Do you take Omeprazole and have Knee deformity?

Check whether Knee deformity is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Knee deformity and when was it recovered:

Expand to all the drugs that have ingredients of omeprazole:

Alternative drugs to, pros and cons of Omeprazole:

Common Omeprazole side effects:

Browse all side effects of Omeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Knee deformity treatments and more:

COVID vaccines that are related to Knee deformity:

Common drugs associated with Knee deformity:

All the drugs that are associated with Knee deformity:

Common conditions associated with Knee deformity:

All the conditions that are associated with Knee deformity:

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole (the active ingredients of Omeprazole) and Omeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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