Ondansetron and Stress cardiomyopathy - a phase IV clinical study of FDA data


Stress cardiomyopathy is found among people who take Ondansetron, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Ondansetron and have Stress cardiomyopathy. It is created by eHealthMe based on reports of 97,041 people who have side effects when taking Ondansetron from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

97,041 people reported to have side effects when taking Ondansetron.
Among them, 93 people (0.1%) have Stress cardiomyopathy.

What is Ondansetron?

Ondansetron has active ingredients of ondansetron. It is often used in nausea. eHealthMe is studying from 97,518 Ondansetron users for its effectiveness, alternative drugs and more.

What is Stress cardiomyopathy?

Stress cardiomyopathy (stress-induced chronic disease of the heart muscle) is found to be associated with 1,265 drugs and 887 conditions by eHealthMe.

Number of Ondansetron and Stress cardiomyopathy reports submitted per year:

Could Ondansetron cause Stress cardiomyopathy?

Time on Ondansetron when people have Stress cardiomyopathy *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Stress cardiomyopathy when taking Ondansetron *:

  • female: 90.8 %
  • male: 9.2 %

Age of people who have Stress cardiomyopathy when taking Ondansetron *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.98 %
  • 40-49: 13.95 %
  • 50-59: 18.6 %
  • 60+: 60.47 %

Common drugs people take besides Ondansetron *:

  1. Fluoxetine: 24 people, 25.81%
  2. Propofol: 9 people, 9.68%
  3. Atropine: 7 people, 7.53%
  4. Oxycodone: 6 people, 6.45%
  5. Calcium: 6 people, 6.45%
  6. Fentanyl: 6 people, 6.45%
  7. Epinephrine: 5 people, 5.38%
  8. Amoxicillin: 5 people, 5.38%
  9. Lidocaine: 5 people, 5.38%
  10. Prednisolone: 5 people, 5.38%

Common side effects people have besides Stress cardiomyopathy *:

  1. Torsade De Pointes (a abnormal heart rate with abnormal beating pattern): 37 people, 39.78%
  2. Electrocardiogram T Wave Inversion: 20 people, 21.51%
  3. Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 17 people, 18.28%
  4. Electrocardiogram Qt Prolonged: 17 people, 18.28%
  5. Fainting (loss of consciousness and postural tone): 15 people, 16.13%
  6. Troponin I Increased: 13 people, 13.98%
  7. Emotional Distress: 13 people, 13.98%
  8. Long Qt Syndrome (disorder of the heart's electrical system): 13 people, 13.98%
  9. Brain Natriuretic Peptide Increased: 13 people, 13.98%
  10. Blood Magnesium Decreased: 13 people, 13.98%

Common conditions people have *:

  1. Depression: 25 people, 26.88%
  2. Pain: 13 people, 13.98%
  3. Sedation: 9 people, 9.68%
  4. High Blood Pressure: 8 people, 8.60%
  5. Autoimmune Hepatitis: 8 people, 8.60%
  6. Hypotension (abnormally low blood pressure): 7 people, 7.53%
  7. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 6 people, 6.45%
  8. Infiltration Anaesthesia: 6 people, 6.45%
  9. Colon Cancer: 5 people, 5.38%
  10. Hepatocellular Carcinoma (liver cancer): 4 people, 4.30%

* Approximation only. Some reports may have incomplete information.

Do you take Ondansetron and have Stress cardiomyopathy?

Check whether Stress cardiomyopathy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Stress cardiomyopathy and when was it recovered:

Expand to all the drugs that have ingredients of ondansetron:

Alternative drugs to, pros and cons of Ondansetron:

Common Ondansetron side effects:

Browse all side effects of Ondansetron:

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Stress cardiomyopathy treatments and more:

COVID vaccines that are related to Stress cardiomyopathy:

Common drugs associated with Stress cardiomyopathy:

All the drugs that are associated with Stress cardiomyopathy:

Common conditions associated with Stress cardiomyopathy:

All the conditions that are associated with Stress cardiomyopathy:

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron (the active ingredients of Ondansetron) and Ondansetron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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