Onglyza and Skin blushing/flushing - a phase IV clinical study of FDA data


Skin blushing/flushing is found among people who take Onglyza, especially for people who are male, 50-59 old.

The phase IV clinical study analyzes which people take Onglyza and have Skin blushing/flushing. It is created by eHealthMe based on reports of 8,238 people who have side effects when taking Onglyza from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 24, 2023

8,238 people reported to have side effects when taking Onglyza.
Among them, 35 people (0.42%) have Skin blushing/flushing.

What is Onglyza?

Onglyza has active ingredients of saxagliptin hydrochloride. It is often used in diabetes. eHealthMe is studying from 8,355 Onglyza users for its effectiveness, alternative drugs and more.

What is Skin blushing/flushing?

Skin blushing/flushing (a sudden reddening of the face, neck) is found to be associated with 3,487 drugs and 2,824 conditions by eHealthMe.

Number of Onglyza and Skin blushing/flushing reports submitted per year:

Could Onglyza cause Skin blushing/flushing?

Gender of people who have Skin blushing/flushing when taking Onglyza *:

  • female: 37.14 %
  • male: 62.86 %

Age of people who have Skin blushing/flushing when taking Onglyza *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 6.25 %
  • 40-49: 6.25 %
  • 50-59: 50.0 %
  • 60+: 37.5 %

Common drugs people take besides Onglyza *:

  1. Niaspan: 14 people, 40.00%
  2. Aspirin: 8 people, 22.86%
  3. Metformin: 7 people, 20.00%
  4. Asa: 7 people, 20.00%
  5. Hydrochlorothiazide: 5 people, 14.29%
  6. Lipitor: 4 people, 11.43%
  7. Lisinopril: 4 people, 11.43%
  8. Fish Oil: 4 people, 11.43%
  9. Crestor: 4 people, 11.43%
  10. Simvastatin: 3 people, 8.57%

Common side effects people have besides Skin blushing/flushing *:

  1. Rashes (redness): 9 people, 25.71%
  2. Feeling Hot: 7 people, 20.00%
  3. Itching: 7 people, 20.00%
  4. Skin Burning Sensation: 4 people, 11.43%
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 11.43%
  6. Dizziness: 3 people, 8.57%
  7. Nausea (feeling of having an urge to vomit): 3 people, 8.57%
  8. Malaise (a feeling of general discomfort or uneasiness): 2 people, 5.71%
  9. Drowsiness: 1 person, 2.86%
  10. Drug Administration Error: 1 person, 2.86%

Common conditions people have *:

  1. High Blood Cholesterol: 12 people, 34.29%
  2. High Density Lipoprotein Decreased: 4 people, 11.43%
  3. Low Density Lipoprotein Increased (cholesterol increased in blood): 2 people, 5.71%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.71%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.86%
  6. Heart Disease: 1 person, 2.86%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 2.86%
  8. Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 1 person, 2.86%
  9. Diarrhea: 1 person, 2.86%
  10. Dyslipidaemia (abnormal amount of lipids): 1 person, 2.86%

* Approximation only. Some reports may have incomplete information.

Do you take Onglyza and have Skin blushing/flushing?

Check whether Skin blushing/flushing is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Skin blushing/flushing and when was it recovered:

Expand to all the drugs that have ingredients of saxagliptin hydrochloride:

Alternative drugs to, pros and cons of Onglyza:

Common Onglyza side effects:

Browse all side effects of Onglyza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Skin blushing/flushing treatments and more:

COVID vaccines that are related to Skin blushing/flushing:

Common drugs associated with Skin blushing/flushing:

All the drugs that are associated with Skin blushing/flushing:

Common conditions associated with Skin blushing/flushing:

All the conditions that are associated with Skin blushing/flushing:

How the study uses the data?

The study uses data from the FDA. It is based on saxagliptin hydrochloride (the active ingredients of Onglyza) and Onglyza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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