Ortho tri-cyclen and Night sweats - a phase IV clinical study of FDA data


Night sweats is found among people who take Ortho tri-cyclen, especially for people who are female, 30-39 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Ortho tri-cyclen and have Night sweats. It is created by eHealthMe based on reports of 4,839 people who have side effects when taking Ortho tri-cyclen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 09, 2023

4,839 people reported to have side effects when taking Ortho tri-cyclen.
Among them, 23 people (0.48%) have Night sweats.

What is Ortho tri-cyclen?

Ortho tri-cyclen has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 5,695 Ortho tri-cyclen users for its effectiveness, alternative drugs and more.

What is Night sweats?

Night sweats (sweating in night) is found to be associated with 2,486 drugs and 1,678 conditions by eHealthMe.

Number of Ortho tri-cyclen and Night sweats reports submitted per year:

Could Ortho tri-cyclen cause Night sweats?

Time on Ortho tri-cyclen when people have Night sweats *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Night sweats when taking Ortho tri-cyclen *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Night sweats when taking Ortho tri-cyclen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 22.73 %
  • 20-29: 27.27 %
  • 30-39: 50.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Ortho tri-cyclen *:

  1. Zithromax: 10 people, 43.48%
  2. Zantac: 8 people, 34.78%
  3. Accutane: 7 people, 30.43%
  4. Klonopin: 7 people, 30.43%
  5. Ambien: 7 people, 30.43%
  6. Amoxicillin: 7 people, 30.43%
  7. Decadron: 6 people, 26.09%
  8. Loprox: 6 people, 26.09%
  9. Elidel: 6 people, 26.09%
  10. Doxycycline: 6 people, 26.09%

Common side effects people have besides Night sweats *:

  1. Weight Decreased: 15 people, 65.22%
  2. Nausea (feeling of having an urge to vomit): 15 people, 65.22%
  3. Panic Disorder: 11 people, 47.83%
  4. Fatigue (feeling of tiredness): 10 people, 43.48%
  5. Insomnia (sleeplessness): 10 people, 43.48%
  6. Breathing Difficulty: 9 people, 39.13%
  7. Urinary Tract Infection: 8 people, 34.78%
  8. Joint Pain: 8 people, 34.78%
  9. Weakness: 7 people, 30.43%
  10. Cough: 7 people, 30.43%

Common conditions people have *:

  1. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 6 people, 26.09%
  2. Depression: 4 people, 17.39%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.35%
  4. Multiple Allergies (allergy to multiple agents): 1 person, 4.35%
  5. Gait Disturbance: 1 person, 4.35%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Ortho tri-cyclen and have Night sweats?

Check whether Night sweats is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Night sweats and when was it recovered:

Expand to all the drugs that have ingredients of ethinyl estradiol; norgestimate:

Alternative drugs to, pros and cons of Ortho tri-cyclen:

Common Ortho tri-cyclen side effects:

Browse all side effects of Ortho tri-cyclen:

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Night sweats treatments and more:

COVID vaccines that are related to Night sweats:

Common drugs associated with Night sweats:

All the drugs that are associated with Night sweats:

Common conditions associated with Night sweats:

All the conditions that are associated with Night sweats:

How the study uses the data?

The study uses data from the FDA. It is based on ethinyl estradiol; norgestimate (the active ingredients of Ortho tri-cyclen) and Ortho tri-cyclen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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