Otezla and Headache - a phase IV clinical study of FDA data

Summary:

We study 133,724 people who have side effects when taking Otezla. Headache is found, especially among people who are female, 50-59 old, have been taking the drug for < 1 month, also take Humira and have Psoriasis.

The phase IV clinical study analyzes which people take Otezla and have Headache. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

What are phase IV trials?

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 08, 2023

133,724 people reported to have side effects when taking Otezla.
Among them, 16,774 people (12.54%) have Headache.

What is Otezla?

Otezla has active ingredients of apremilast. It is used in psoriatic arthritis. Currently, eHealthMe is studying from 141,607 Otezla users.

What is Headache?

Headache (pain in head) is found to be associated with 5,284 drugs and 5,646 conditions by eHealthMe. Currently, we are studying 714,741 people who have Headache.

Number of Otezla and Headache reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Otezla and have Headache?

Check whether Headache is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Headache and when was it recovered:

Headache in Otezla

Expand to all the drugs that have ingredients of apremilast:

Headache and drugs with ingredients of apremilast (14,927 reports)

Alternative drugs to, pros and cons of Otezla:

Otezla (141,607 reports)

Browse all side effects of Otezla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Headache treatments and more:

Headache (714,741 reports)

Common drugs associated with Headache:

All the drugs that are associated with Headache:

Headache (5,284 drugs)

Common conditions associated with Headache:

Multiple sclerosis: 41,461 reports
Rheumatoid arthritis: 40,932 reports
High blood pressure: 24,649 reports
Primary pulmonary hypertension: 21,717 reports
Psoriasis: 21,398 reports

All the conditions that are associated with Headache:

Headache (5,646 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on apremilast (the active ingredients of Otezla) and Otezla (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.