Oxaliplatin and Sick sinus syndrome - a phase IV clinical study of FDA data


Sick sinus syndrome is found among people who take Oxaliplatin, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Oxaliplatin and have Sick sinus syndrome. It is created by eHealthMe based on reports of 50,484 people who have side effects when taking Oxaliplatin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 22, 2022

50,484 people reported to have side effects when taking Oxaliplatin.
Among them, 8 people (0.02%) have Sick sinus syndrome.

What is Oxaliplatin?

Oxaliplatin has active ingredients of oxaliplatin. It is often used in colon cancer. eHealthMe is studying from 50,569 Oxaliplatin users for its effectiveness, alternative drugs and more.

What is Sick sinus syndrome?

Sick sinus syndrome (a collection of heart rhythm disorders) is found to be associated with 1,242 drugs and 710 conditions by eHealthMe.

Number of Oxaliplatin and Sick sinus syndrome reports submitted per year:

Could Oxaliplatin cause Sick sinus syndrome?

Time on Oxaliplatin when people have Sick sinus syndrome *:

  • < 1 month: 16.67 %
  • 1 - 6 months: 83.33 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Sick sinus syndrome when taking Oxaliplatin *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Sick sinus syndrome when taking Oxaliplatin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 83.33 %

Common drugs people take besides Oxaliplatin *:

  1. Paracetamol: 5 people, 62.50%
  2. Apixaban: 5 people, 62.50%
  3. Fluorouracil: 1 person, 12.50%

Common side effects people have besides Sick sinus syndrome *:

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 75.00%
  2. Pneumonia: 5 people, 62.50%
  3. Fever: 5 people, 62.50%
  4. Dyspnea Exertional: 5 people, 62.50%
  5. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 4 people, 50.00%
  6. Neoplasm Progression (growth of tumour): 1 person, 12.50%
  7. Loss Of Consciousness: 1 person, 12.50%
  8. Liver Disorder (liver diseases): 1 person, 12.50%
  9. Cholecystitis (infection of gallbladder): 1 person, 12.50%
  10. Bradycardia (abnormally slow heart action): 1 person, 12.50%

Common conditions people have *:

  1. Colorectal Cancer Stage Iii (colon and rectal cancer spreads to lymph nodes): 5 people, 62.50%
  2. Oesophageal Carcinoma (cancer tumour of oesophagus): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Oxaliplatin and have Sick sinus syndrome?

Check whether Sick sinus syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Expand to all the drugs that have ingredients of oxaliplatin:

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Common Oxaliplatin side effects:

Browse all side effects of Oxaliplatin:

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Sick sinus syndrome treatments and more:

COVID vaccines that are related to Sick sinus syndrome:

Common drugs associated with Sick sinus syndrome:

All the drugs that are associated with Sick sinus syndrome:

Common conditions associated with Sick sinus syndrome:

All the conditions that are associated with Sick sinus syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on oxaliplatin (the active ingredients of Oxaliplatin) and Oxaliplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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