Palonosetron and Myocarditis - a phase IV clinical study of FDA data


Myocarditis is reported only by a few people who take Palonosetron.

The phase IV clinical study analyzes which people take Palonosetron and have Myocarditis. It is created by eHealthMe based on reports of 4,506 people who have side effects while taking Palonosetron from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 05, 2023

4,506 people reported to have side effects when taking Palonosetron.
Among them, 2 people (0.04%) have Myocarditis.

What is Palonosetron?

Palonosetron has active ingredients of palonosetron hydrochloride. eHealthMe is studying from 4,517 Palonosetron users for its effectiveness, alternative drugs and more.

What is Myocarditis?

Myocarditis (inflammation of heart muscle myocardium) is found to be associated with 1,303 drugs and 821 conditions by eHealthMe.

Number of Palonosetron and Myocarditis reports submitted per year:

Could Palonosetron cause Myocarditis?

Time on Palonosetron when people have Myocarditis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Myocarditis when taking Palonosetron *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Myocarditis when taking Palonosetron *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 50 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 0.0 %

Common drugs people take besides Palonosetron *:

  1. Famotidine: 2 people, 100.00%
  2. Zyprexa: 1 person, 50.00%
  3. Voltaren: 1 person, 50.00%
  4. Aprepitant: 1 person, 50.00%
  5. Avastin: 1 person, 50.00%
  6. Bumetanide: 1 person, 50.00%
  7. Carboplatin: 1 person, 50.00%
  8. Clozaril: 1 person, 50.00%
  9. Coenzyme Q10: 1 person, 50.00%
  10. Emend: 1 person, 50.00%

Common side effects people have besides Myocarditis *:

  1. Thrombocytopenia (decrease of platelets in blood): 1 person, 50.00%
  2. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 1 person, 50.00%
  3. Renal Disorder (kidney disease): 1 person, 50.00%
  4. Pulmonary Congestion (congestion in the lungs): 1 person, 50.00%
  5. Left Ventricular Failure (left ventricle fails to contract forcefully): 1 person, 50.00%
  6. Ileus Paralytic (obstruction of the intestine due to paralysis of the intestinal muscles): 1 person, 50.00%
  7. Hypotension (abnormally low blood pressure): 1 person, 50.00%
  8. Hyperphosphatasaemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 50.00%
  9. Fever: 1 person, 50.00%
  10. Ejection Fraction Decreased (systolic heart failure): 1 person, 50.00%

Common conditions people have *:

  1. Urination - Excessive Volume: 1 person, 50.00%
  2. Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 50.00%
  3. Nausea (feeling of having an urge to vomit): 1 person, 50.00%
  4. Lung Cancer - Non-Small Cell (lung cancer): 1 person, 50.00%
  5. Hypertrophy (increase in the volume of an organ or tissue due to the enlargement of its component cells): 1 person, 50.00%
  6. Enlarged Prostate: 1 person, 50.00%
  7. Endometrial Cancer: 1 person, 50.00%
  8. Cough: 1 person, 50.00%
  9. Cardiomyopathy (weakening of the heart muscle): 1 person, 50.00%
  10. Blood Electrolytes Abnormal: 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Palonosetron and have Myocarditis?

Check whether Myocarditis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Myocarditis and when was it recovered:

Expand to all the drugs that have ingredients of palonosetron hydrochloride:

Alternative drugs to, pros and cons of Palonosetron:

Common Palonosetron side effects:

Browse all side effects of Palonosetron:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Myocarditis treatments and more:

COVID vaccines that are related to Myocarditis:

Common drugs associated with Myocarditis:

All the drugs that are associated with Myocarditis:

Common conditions associated with Myocarditis:

All the conditions that are associated with Myocarditis:

How the study uses the data?

The study uses data from the FDA. It is based on palonosetron hydrochloride (the active ingredients of Palonosetron) and Palonosetron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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