Paracetamol and Amputation - from FDA reports

Amputation is reported only by a few people who take Paracetamol. We study 39,207 people who have side effects while taking Paracetamol from FDA. Among them, 3 have Amputation. Find out below who they are, when they have Amputation and more.

On Jul, 11, 2018

39,207 people reported to have side effects when taking Paracetamol.
Among them, 3 people (0.01%) have Amputation

Number of reports submitted per year:

Could Paracetamol cause Amputation?

Gender of people who have Amputation when taking Paracetamol *:

  • female: 33.33 %
  • male: 66.67 %

Age of people who have Amputation when taking Paracetamol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Top conditions involved for these people *:

  1. Type 2 Diabetes: 2 people, 66.67%
  2. Stress And Anxiety: 2 people, 66.67%
  3. Hyperglycemia (high blood sugar): 2 people, 66.67%
  4. High Blood Pressure: 2 people, 66.67%
  5. Dyslipidaemia (abnormal amount of lipids): 2 people, 66.67%

Top co-used drugs for these people *:

  1. Metformin: 2 people, 66.67%
  2. Clopidogrel: 2 people, 66.67%
  3. Tracleer: 1 person, 33.33%
  4. Percocet: 1 person, 33.33%
  5. Oxycontin: 1 person, 33.33%

Top other side effects for these people *:

  1. Peripheral Ischaemia (impaired circulation to an extremity): 2 people, 66.67%
  2. Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 33.33%
  3. Postoperative Wound Infection: 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

What's next:

You could also:

Related studies


Paracetamol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Paracetamol 39,806 users)


Amputation has been reported by people with diabetes, rheumatoid arthritis, type 2 diabetes, pain, multiple sclerosis (latest reports from 676 Amputation patients).

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What would happen?

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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