Paracetamol and Anal prolapse - a phase IV clinical study of FDA data

Summary:

Anal prolapse is found among people who take Paracetamol, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Paracetamol and have Anal prolapse. It is created by eHealthMe based on reports of 109,289 people who have side effects when taking Paracetamol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On May, 22, 2022

109,289 people reported to have side effects when taking Paracetamol.
Among them, 18 people (0.02%) have Anal prolapse.


What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 110,074 Paracetamol users for its effectiveness, alternative drugs and more.

What is Anal prolapse?

Anal prolapse (protrusion of rectal tissue through the anus to the exterior of the body) is found to be associated with 97 drugs and 64 conditions by eHealthMe.

Number of Paracetamol and Anal prolapse reports submitted per year:

Could Paracetamol cause Anal prolapse?

Time on Paracetamol when people have Anal prolapse *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anal prolapse when taking Paracetamol *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Anal prolapse when taking Paracetamol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 0.0 %
  • 60+: 92.86 %

Common drugs people take besides Paracetamol *:

  1. Amlodipine: 13 people, 72.22%
  2. Pantoprazole: 11 people, 61.11%
  3. Euthyrox: 11 people, 61.11%
  4. Diovan: 10 people, 55.56%
  5. Vitamin C: 6 people, 33.33%
  6. Magnesium: 6 people, 33.33%
  7. Humira: 6 people, 33.33%
  8. Sutent: 1 person, 5.56%
  9. Movicol: 1 person, 5.56%
  10. Metoprolol Tartrate: 1 person, 5.56%

Common side effects people have besides Anal prolapse *:

  1. Urinary Tract Infection: 17 people, 94.44%
  2. Weakness: 17 people, 94.44%
  3. Anaemia (lack of blood): 17 people, 94.44%
  4. Weight Decreased: 17 people, 94.44%
  5. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 16 people, 88.89%
  6. Gait Disturbance: 12 people, 66.67%
  7. Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 12 people, 66.67%
  8. Urination - Excessive At Night: 12 people, 66.67%
  9. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 12 people, 66.67%
  10. Hypokalemia (low potassium): 11 people, 61.11%

Common conditions people have *:

  1. High Blood Pressure: 7 people, 38.89%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 33.33%
  3. High Blood Cholesterol: 6 people, 33.33%
  4. Gastric Disorder (disease of stomach): 6 people, 33.33%
  5. Cardiac Disorder: 6 people, 33.33%
  6. Renal Cell Carcinoma (a kidney cancer): 1 person, 5.56%
  7. Nasopharyngitis (inflammation of the nasopharynx): 1 person, 5.56%
  8. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 1 person, 5.56%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Anal prolapse?

Check whether Anal prolapse is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of Paracetamol:

Anal prolapse treatments and more:

COVID vaccines that are related to Anal prolapse:

How severe was Anal prolapse and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen:

All the drugs that are associated with Anal prolapse:

All the conditions that are associated with Anal prolapse:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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