Paracetamol and Laryngitis - a phase IV clinical study of FDA data


Laryngitis is found among people who take Paracetamol, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Paracetamol and have Laryngitis. It is created by eHealthMe based on reports of 114,125 people who have side effects when taking Paracetamol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 26, 2022

114,125 people reported to have side effects when taking Paracetamol.
Among them, 32 people (0.03%) have Laryngitis.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 114,973 Paracetamol users for its effectiveness, alternative drugs and more.

What is Laryngitis?

Laryngitis (inflammation of the larynx) is found to be associated with 1,412 drugs and 794 conditions by eHealthMe.

Number of Paracetamol and Laryngitis reports submitted per year:

Could Paracetamol cause Laryngitis?

Time on Paracetamol when people have Laryngitis *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Laryngitis when taking Paracetamol *:

  • female: 96.55 %
  • male: 3.45 %

Age of people who have Laryngitis when taking Paracetamol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.7 %
  • 40-49: 22.22 %
  • 50-59: 25.93 %
  • 60+: 48.15 %

Common drugs people take besides Paracetamol *:

  1. Zometa: 6 people, 18.75%
  2. Avastin: 6 people, 18.75%
  3. Methotrexate: 2 people, 6.25%
  4. Actemra: 2 people, 6.25%
  5. Vitamin D3: 2 people, 6.25%
  6. Altace: 2 people, 6.25%
  7. Synthroid: 2 people, 6.25%
  8. Flonase: 2 people, 6.25%
  9. Singulair: 2 people, 6.25%
  10. Proventil: 2 people, 6.25%

Common side effects people have besides Laryngitis *:

  1. Nasopharyngitis (inflammation of the nasopharynx): 12 people, 37.50%
  2. Weakness: 9 people, 28.12%
  3. High Blood Pressure: 9 people, 28.12%
  4. Rashes (redness): 9 people, 28.12%
  5. Diarrhea: 9 people, 28.12%
  6. Hoarseness Or Changing Voice: 9 people, 28.12%
  7. Pain In Extremity: 8 people, 25.00%
  8. Tooth Abscess (pus formation in tooth): 7 people, 21.88%
  9. Nosebleed (bleeding from nose): 7 people, 21.88%
  10. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 6 people, 18.75%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 21.88%
  2. Toothaches (tooth pain): 6 people, 18.75%
  3. Breast Cancer: 5 people, 15.62%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 9.38%
  5. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 9.38%
  6. Menopause (end of monthly cycles in women): 3 people, 9.38%
  7. High Blood Pressure: 2 people, 6.25%
  8. Multiple Myeloma (cancer of the plasma cells): 2 people, 6.25%
  9. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 3.12%
  10. Diabetes: 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and have Laryngitis?

Check whether Laryngitis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Laryngitis and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen:

Alternative drugs to, pros and cons of Paracetamol:

Common Paracetamol side effects:

Browse all side effects of Paracetamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Laryngitis treatments and more:

COVID vaccines that are related to Laryngitis:

Common drugs associated with Laryngitis:

All the drugs that are associated with Laryngitis:

Common conditions associated with Laryngitis:

All the conditions that are associated with Laryngitis:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Paracetamol) and Paracetamol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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