Paxil and Decreased immune responsiveness - a phase IV clinical study of FDA data


Decreased immune responsiveness is found among people who take Paxil, especially for people who are female, 10-19 old.

The phase IV clinical study analyzes which people take Paxil and have Decreased immune responsiveness. It is created by eHealthMe based on reports of 87,385 people who have side effects when taking Paxil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2022

87,385 people reported to have side effects when taking Paxil.
Among them, 8 people (0.01%) have Decreased immune responsiveness.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 91,143 Paxil users for its effectiveness, alternative drugs and more.

What is Decreased immune responsiveness?

Decreased immune responsiveness is found to be associated with 1,204 drugs and 704 conditions by eHealthMe.

Number of Paxil and Decreased immune responsiveness reports submitted per year:

Could Paxil cause Decreased immune responsiveness?

Gender of people who have Decreased immune responsiveness when taking Paxil *:

  • female: 75 %
  • male: 25 %

Age of people who have Decreased immune responsiveness when taking Paxil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 50 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 25 %
  • 50-59: 0.0 %
  • 60+: 25 %

Common drugs people take besides Paxil *:

  1. Folic Acid: 3 people, 37.50%
  2. Sulfasalazine: 2 people, 25.00%
  3. Enbrel: 2 people, 25.00%
  4. Lyrica: 2 people, 25.00%
  5. Zyrtec: 1 person, 12.50%
  6. Humira: 1 person, 12.50%
  7. Benicar: 1 person, 12.50%
  8. Celebrex: 1 person, 12.50%
  9. Cosentyx: 1 person, 12.50%
  10. Crestor: 1 person, 12.50%

Common side effects people have besides Decreased immune responsiveness *:

  1. Malaise (a feeling of general discomfort or uneasiness): 3 people, 37.50%
  2. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 37.50%
  3. Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 25.00%
  4. Drug Hypersensitivity: 2 people, 25.00%
  5. Injection Site Reaction: 2 people, 25.00%
  6. Injection Site Swelling: 2 people, 25.00%
  7. Injection Site Warmth: 2 people, 25.00%
  8. Fever: 2 people, 25.00%
  9. Oral Pruritus (itching in mouth): 2 people, 25.00%
  10. Erythema Nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below): 2 people, 25.00%

Common conditions people have *:

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 25.00%
  2. Migraine (headache): 2 people, 25.00%
  3. Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 2 people, 25.00%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 25.00%
  5. Thyroid Diseases: 1 person, 12.50%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 12.50%
  7. Panic Disorder: 1 person, 12.50%
  8. Itching: 1 person, 12.50%
  9. Breakthrough Pain: 1 person, 12.50%
  10. Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Decreased immune responsiveness?

Check whether Decreased immune responsiveness is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Decreased immune responsiveness and when was it recovered:

Expand to all the drugs that have ingredients of paroxetine hydrochloride:

Alternative drugs to, pros and cons of Paxil:

Common Paxil side effects:

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Decreased immune responsiveness treatments and more:

COVID vaccines that are related to Decreased immune responsiveness:

Common drugs associated with Decreased immune responsiveness:

All the drugs that are associated with Decreased immune responsiveness:

Common conditions associated with Decreased immune responsiveness:

All the conditions that are associated with Decreased immune responsiveness:

How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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