Pentasa and Crohn's disease - a phase IV clinical study of FDA data

Summary:

Crohn's disease is found among people who take Pentasa, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Pentasa and have Crohn's disease. It is created by eHealthMe based on reports of 19,036 people who have side effects when taking Pentasa from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 12, 2023

19,036 people reported to have side effects when taking Pentasa.
Among them, 1,718 people (9.03%) have Crohn's disease.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 19,557 Pentasa users for its effectiveness, alternative drugs and more.

What is Crohn's disease?

Crohn's disease (condition that causes inflammation of the gastrointestinal tract) is found to be associated with 2,521 drugs and 1,970 conditions by eHealthMe.

Number of Pentasa and Crohn's disease reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Pentasa and have Crohn's disease?

Check whether Crohn's disease is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .

Related studies

How severe was Crohn's disease and when was it recovered:

Crohn's disease in Pentasa

Expand to all the drugs that have ingredients of mesalamine:

Crohn's disease and drugs with ingredients of mesalamine (4,136 reports)

Alternative drugs to, pros and cons of Pentasa:

Pentasa (19,557 reports)

Common Pentasa side effects:

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Crohn's disease treatments and more:

Crohn's disease (311,603 reports)

COVID vaccines that are related to Crohn's disease:

Common drugs associated with Crohn's disease:

All the drugs that are associated with Crohn's disease:

Crohn's disease (2,521 drugs)

Common conditions associated with Crohn's disease:

Acne: 4,791 reports
Rheumatoid arthritis: 1,983 reports
Pain: 1,966 reports
High blood pressure: 1,721 reports

All the conditions that are associated with Crohn's disease:

Crohn's disease (1,970 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mesalamine (the active ingredients of Pentasa) and Pentasa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.