Pepcid ac and Kidney malformation - a phase IV clinical study of FDA data


Kidney malformation is reported only by a few people who take Pepcid Ac.

The phase IV clinical study analyzes which people take Pepcid ac and have Kidney malformation. It is created by eHealthMe based on reports of 8,255 people who have side effects while taking Pepcid ac from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 24, 2023

8,255 people reported to have side effects when taking Pepcid ac.
Among them, 3 people (0.04%) have Kidney malformation.

What is Pepcid ac?

Pepcid ac has active ingredients of famotidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,519 Pepcid ac users for its effectiveness, alternative drugs and more.

What is Kidney malformation?

Kidney malformation (kidneys that have not developed properly) is found to be associated with 261 drugs and 106 conditions by eHealthMe.

Number of Pepcid ac and Kidney malformation reports submitted per year:

Could Pepcid ac cause Kidney malformation?

Time on Pepcid ac when people have Kidney malformation *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Kidney malformation when taking Pepcid ac *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Kidney malformation when taking Pepcid ac *:

  • 0-1: 33.33 %
  • 2-9: 66.67 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Pepcid ac *:

  1. Lamisil: 3 people, 100.00%
  2. Cordran: 3 people, 100.00%
  3. Dha: 2 people, 66.67%
  4. Vitamins: 1 person, 33.33%
  5. Progesterone: 1 person, 33.33%
  6. Clotrimazole: 1 person, 33.33%

Common side effects people have besides Kidney malformation *:

  1. Tumor: 3 people, 100.00%
  2. Post Procedural Complication: 3 people, 100.00%
  3. Maternal Exposure Before Pregnancy (use of substance before pregnancy): 3 people, 100.00%
  4. Coloboma (a hole in one of the structures of the eye, such as the iris, retina, choroid or optic disc): 3 people, 100.00%
  5. Cataract (clouding of the lens inside the eye): 3 people, 100.00%
  6. Accident: 3 people, 100.00%
  7. Unilateral Hydronephrosis (kidney stone that causes obstruction of the ureter): 1 person, 33.33%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 100.00%
  2. Pityriasis (a skin disease characterized by the shedding of fine flaky scales): 3 people, 100.00%
  3. Nasopharyngitis (inflammation of the nasopharynx): 3 people, 100.00%
  4. Hypersensitivity: 3 people, 100.00%
  5. Birth Control: 3 people, 100.00%
  6. Acne (skin problems that cause pimples): 3 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pepcid ac and have Kidney malformation?

Check whether Kidney malformation is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Kidney malformation and when was it recovered:

Expand to all the drugs that have ingredients of famotidine:

Alternative drugs to, pros and cons of Pepcid ac:

Common Pepcid ac side effects:

Browse all side effects of Pepcid ac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Kidney malformation treatments and more:

COVID vaccines that are related to Kidney malformation:

All the drugs that are associated with Kidney malformation:

All the conditions that are associated with Kidney malformation:

How the study uses the data?

The study uses data from the FDA. It is based on famotidine (the active ingredients of Pepcid ac) and Pepcid ac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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