Phenergan and Respiratory distress syndrome (rds) in infants - a phase IV clinical study of FDA data

Summary:

We study 23,846 people who have side effects when taking Phenergan. Respiratory distress syndrome (rds) in infants is found, especially among people who are male, 0-1 old, have been taking the drug for < 1 month, also take Tylenol and have Depression.

The phase IV clinical study analyzes which people take Phenergan and have Respiratory distress syndrome (rds) in infants. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 29, 2023

23,846 people reported to have side effects when taking Phenergan.
Among them, 25 people (0.1%) have Respiratory distress syndrome (rds) in infants.

What is Phenergan?

Phenergan has active ingredients of promethazine hydrochloride. It is used in nausea. Currently, eHealthMe is studying from 24,896 Phenergan users.

What is Respiratory distress syndrome (rds) in infants?

Respiratory distress syndrome (rds) in infants (respiratory disease of newborn babies, especially premature babies, characterized by distressful breathing, cyanosis, and the formation of a glassy membrane over the alveoli of the lungs) is found to be associated with 1,039 drugs and 813 conditions by eHealthMe. Currently, we are studying 5,652 people who have Respiratory distress syndrome (rds) in infants.

Number of Phenergan and Respiratory distress syndrome (rds) in infants reports submitted per year:

Could Phenergan cause Respiratory distress syndrome (rds) in infants?

Time on Phenergan when people have Respiratory distress syndrome (rds) in infants *:

Gender of people who have Respiratory distress syndrome (rds) in infants when taking Phenergan *:

female: 50 %
male: 50 %

Age of people who have Respiratory distress syndrome (rds) in infants when taking Phenergan *:

Common drugs people take besides Phenergan *:

Common side effects people have besides Respiratory distress syndrome (rds) in infants *:

Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 12 people, 48.00%
Premature Baby: 12 people, 48.00%
Bronchopulmonary Dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type): 6 people, 24.00%
Cyanosis Neonatal (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails in newborn): 5 people, 20.00%
Neonatal Tachycardia (an abnormal rapidity of heart action that usually is defined as a heart rate more than 100 beats/min): 4 people, 16.00%
Breech Presentation: 4 people, 16.00%
Blood Thyroid Stimulating Hormone Increased: 4 people, 16.00%
Haemoglobin Decreased: 4 people, 16.00%
Thrombocythaemia (an increased number of platelets in the circulating blood): 4 people, 16.00%
Hypotonia (low muscle tone): 4 people, 16.00%

Common conditions people have *:

Depression: 6 people, 24.00%
Stress And Anxiety: 3 people, 12.00%
Pain: 3 people, 12.00%
Migraine (headache): 3 people, 12.00%
Premature Rupture Of Membranes: 2 people, 8.00%
Premature Labor: 2 people, 8.00%
Immature Respiratory System: 2 people, 8.00%
Birth Control: 2 people, 8.00%
Bipolar Disorder (mood disorder): 2 people, 8.00%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Phenergan and have Respiratory distress syndrome (rds) in infants?

Check whether Respiratory distress syndrome (rds) in infants is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

Related studies

Phenergan side effects by duration, gender and age:

Phenergan side effects (24,896 reports)

Respiratory distress syndrome (rds) in infants treatments and more:

Respiratory distress syndrome (rds) in infants (5,652 reports)

Common drugs associated with Respiratory distress syndrome (rds) in infants:

All the drugs that are associated with Respiratory distress syndrome (rds) in infants:

Respiratory distress syndrome (rds) in infants (1,039 drugs)

Common conditions associated with Respiratory distress syndrome (rds) in infants:

Depression: 478 reports
Hiv infection: 130 reports
Epilepsy: 128 reports
High blood pressure: 125 reports
Stress and anxiety: 119 reports

All the conditions that are associated with Respiratory distress syndrome (rds) in infants:

Respiratory distress syndrome (rds) in infants (813 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on promethazine hydrochloride (the active ingredients of Phenergan) and Phenergan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.