Phenytoin and Diarrhea - a phase IV clinical study of FDA data


Diarrhea is found among people who take Phenytoin, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Phenytoin and have Diarrhea. It is created by eHealthMe based on reports of 13,120 people who have side effects when taking Phenytoin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 03, 2023

13,120 people reported to have side effects when taking Phenytoin.
Among them, 249 people (1.9%) have Diarrhea.

What is Phenytoin?

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. eHealthMe is studying from 13,400 Phenytoin users for its effectiveness, alternative drugs and more.

What is Diarrhea?

Diarrhea is found to be associated with 4,749 drugs and 5,499 conditions by eHealthMe.

Number of Phenytoin and Diarrhea reports submitted per year:

Could Phenytoin cause Diarrhea?

Time on Phenytoin when people have Diarrhea *:

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Gender of people who have Diarrhea when taking Phenytoin*:

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Age of people who have Diarrhea when taking Phenytoin *:

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Common drugs people take besides Phenytoin *:

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Common side effects people have besides Diarrhea *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Phenytoin and have Diarrhea?

Check whether Diarrhea is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

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Common conditions associated with Diarrhea:

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How the study uses the data?

The study uses data from the FDA. It is based on phenytoin (the active ingredients of Phenytoin) and Phenytoin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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