Phenytoin and Drug abuse - from FDA reports

Drug abuse is found among people who take Phenytoin, especially for people who are male, 40-49 old , have been taking the drug for < 1 month, also take medication Diazepam, and have Depression. This review analyzes which people have Drug abuse with Phenytoin. It is created by eHealthMe based on reports of 12,079 people who have side effects when taking Phenytoin from FDA , and is updated regularly.


On Jun, 17, 2018

12,079 people reported to have side effects when taking Phenytoin.
Among them, 58 people (0.48%) have Drug abuse

Number of reports submitted per year:

Could Phenytoin cause Drug abuse?

Time on Phenytoin when people have Drug abuse *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Drug abuse when taking Phenytoin *:

  • female: 33.93 %
  • male: 66.07 %

Age of people who have Drug abuse when taking Phenytoin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.85 %
  • 20-29: 9.26 %
  • 30-39: 16.67 %
  • 40-49: 29.63 %
  • 50-59: 14.81 %
  • 60+: 27.78 %

Top conditions involved for these people *:

  1. Pain: 5 people, 8.62%
  2. Depression: 5 people, 8.62%
  3. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 6.90%
  4. Metastases To Spine (cancer spreads to spine): 4 people, 6.90%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 6.90%
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Top co-used drugs for these people *:

  1. Diazepam: 12 people, 20.69%
  2. Fluoxetine: 11 people, 18.97%
  3. Alprazolam: 11 people, 18.97%
  4. Fentanyl: 10 people, 17.24%
  5. Oxycodone: 8 people, 13.79%
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Top other side effects for these people *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 17.24%
  2. Cardiac Arrest: 9 people, 15.52%
  3. Completed Suicide (act of taking one's own life): 7 people, 12.07%
  4. Breathing - Slowed Or Stopped: 7 people, 12.07%
  5. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 6 people, 10.34%
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* Approximation only. Some reports may have incomplete information.

What's next:

Do you take Phenytoin and have Drug abuse?

Related studies


Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. (latest outcomes from Phenytoin 12,332 users)

Drug abuse

Drug abuse has been reported by people with drug abuse and dependence, drug abuse, pain, depression (latest reports from 42,975 Drug abuse patients).

Drugs that are associated with Drug abuse
Drug abuse (1,591 drugs)
Could your condition cause Drug abuse
Drug abuse (1,271 conditions)
Phenytoin side effects
Browse all side effects of Phenytoin
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Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

What would happen?

Predict new side effects and undetected conditions when you take Phenytoin and have Drug abuse

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