Phenytoin and Drug abuse - from FDA reports


Drug abuse is found among people who take Phenytoin, especially for people who are male, 40-49 old , have been taking the drug for < 1 month, also take medication Diazepam, and have Depression. This study is created by eHealthMe based on reports of 12,086 people who have side effects when taking Phenytoin from FDA, and is updated regularly.

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On Oct, 18, 2018

12,086 people reported to have side effects when taking Phenytoin.
Among them, 58 people (0.48%) have Drug abuse


Number of reports submitted per year:

Could Phenytoin cause Drug abuse?

Time on Phenytoin when people have Drug abuse *:

Gender of people who have Drug abuse when taking Phenytoin *:

  • female: 33.93 %
  • male: 66.07 %

Age of people who have Drug abuse when taking Phenytoin *:

Top conditions involved for these people *:

  1. Pain: 5 people, 8.62%
  2. Depression: 5 people, 8.62%
  3. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 6.90%
  4. Metastases To Spine (cancer spreads to spine): 4 people, 6.90%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 6.90%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Diazepam: 12 people, 20.69%
  2. Fluoxetine: 11 people, 18.97%
  3. Alprazolam: 11 people, 18.97%
  4. Fentanyl: 10 people, 17.24%
  5. Oxycodone: 8 people, 13.79%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 17.24%
  2. Cardiac Arrest: 9 people, 15.52%
  3. Completed Suicide (act of taking one's own life): 7 people, 12.07%
  4. Breathing - Slowed Or Stopped: 7 people, 12.07%
  5. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 6 people, 10.34%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study



Do you have Drug abuse while taking Phenytoin?


You are not alone:




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Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. (latest outcomes from Phenytoin 12,339 users)

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Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

What would happen?

Predict new side effects and undetected conditions when you take Phenytoin and have Drug abuse


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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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