Phenytoin and Drug abuse - from FDA reports

Drug abuse is found among people who take Phenytoin, especially for people who are male, 40-49 old , have been taking the drug for < 1 month, also take medication Diazepam, and have Depression. This study is created by eHealthMe based on reports of 12,079 people who have side effects when taking Phenytoin from FDA, and is updated regularly.

Who is eHealthMe: we are a data analysis company who specializes in health care industry. Our independent and original studies have been referenced on 400+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and EANO.

On Aug, 19, 2018

12,079 people reported to have side effects when taking Phenytoin.
Among them, 58 people (0.48%) have Drug abuse

Number of reports submitted per year:

Could Phenytoin cause Drug abuse?

Time on Phenytoin when people have Drug abuse *:

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Drug abuse when taking Phenytoin *:

  • female: 33.93 %
  • male: 66.07 %

Age of people who have Drug abuse when taking Phenytoin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.85 %
  • 20-29: 9.26 %
  • 30-39: 16.67 %
  • 40-49: 29.63 %
  • 50-59: 14.81 %
  • 60+: 27.78 %

Top conditions involved for these people *:

  1. Pain: 5 people, 8.62%
  2. Depression: 5 people, 8.62%
  3. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 6.90%
  4. Metastases To Spine (cancer spreads to spine): 4 people, 6.90%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 6.90%
Check whether a drug or a condition causes Drug abuse

Top co-used drugs for these people *:

  1. Diazepam: 12 people, 20.69%
  2. Fluoxetine: 11 people, 18.97%
  3. Alprazolam: 11 people, 18.97%
  4. Fentanyl: 10 people, 17.24%
  5. Oxycodone: 8 people, 13.79%
Subscribe to monitor Drug abuse in Phenytoin

Top other side effects for these people *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 17.24%
  2. Cardiac Arrest: 9 people, 15.52%
  3. Completed Suicide (act of taking one's own life): 7 people, 12.07%
  4. Breathing - Slowed Or Stopped: 7 people, 12.07%
  5. Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 6 people, 10.34%
Click here to get more results

* Approximation only. Some reports may have incomplete information.

Are you new to Phenytoin or have questions?

Volunteer or get paid to help people with your care experience

Related studies


Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. (latest outcomes from Phenytoin 12,332 users)

Drug abuse

Drug abuse has been reported by people with drug abuse and dependence, drug abuse, pain, depression (latest reports from 42,976 Drug abuse patients).

Drugs that are associated with Drug abuse
Drug abuse (998 drugs)
Could your condition cause Drug abuse
Drug abuse (1,271 conditions)
Phenytoin side effects
Browse all side effects of Phenytoin
a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

What would happen?

Predict new side effects and undetected conditions when you take Phenytoin and have Drug abuse

You are not alone. Join our personalized support groups:

You may be interested in these posts

More posts for: Phenytoin, Drug abuse

Recent updates

General studies
Active Support Groups
Recent Care Guides

You could also:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.