Plendil and Spinal column stenosis - a phase IV clinical study of FDA data


Spinal column stenosis is found among people who take Plendil, especially for people who are female, 60+ old, have been taking the drug for 10+ years.

The phase IV clinical study analyzes which people take Plendil and have Spinal column stenosis. It is created by eHealthMe based on reports of 4,838 people who have side effects when taking Plendil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2022

4,838 people reported to have side effects when taking Plendil.
Among them, 11 people (0.23%) have Spinal column stenosis.

What is Plendil?

Plendil has active ingredients of felodipine. It is often used in high blood pressure. eHealthMe is studying from 4,928 Plendil users for its effectiveness, alternative drugs and more.

What is Spinal column stenosis?

Spinal column stenosis (narrowing of spinal column) is found to be associated with 1,347 drugs and 671 conditions by eHealthMe.

Number of Plendil and Spinal column stenosis reports submitted per year:

Could Plendil cause Spinal column stenosis?

Time on Plendil when people have Spinal column stenosis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

Gender of people who have Spinal column stenosis when taking Plendil *:

  • female: 63.64 %
  • male: 36.36 %

Age of people who have Spinal column stenosis when taking Plendil *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 42.86 %
  • 60+: 57.14 %

Common drugs people take besides Plendil *:

  1. Vitamin C: 4 people, 36.36%
  2. Prevacid: 4 people, 36.36%
  3. Asa: 4 people, 36.36%
  4. Zometa: 4 people, 36.36%
  5. Lecithin: 3 people, 27.27%
  6. Bactrim: 3 people, 27.27%
  7. Morphine: 3 people, 27.27%
  8. Mobic: 3 people, 27.27%
  9. Lutein: 3 people, 27.27%
  10. Pomalyst: 3 people, 27.27%

Common side effects people have besides Spinal column stenosis *:

  1. Intervertebral Disc Protrusion (spinal disc protrusion): 6 people, 54.55%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 54.55%
  3. Back Pain: 5 people, 45.45%
  4. Cardiac Murmur (an heart sound in valve abnormality): 5 people, 45.45%
  5. Dehydration (dryness resulting from the removal of water): 4 people, 36.36%
  6. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 36.36%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 36.36%
  8. Fatigue (feeling of tiredness): 4 people, 36.36%
  9. Oedema (fluid collection in tissue): 4 people, 36.36%
  10. Intervertebral Disc Operation: 3 people, 27.27%

Common conditions people have *:

  1. Back Pain: 5 people, 45.45%
  2. Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
  3. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 3 people, 27.27%
  4. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 27.27%
  5. Blood Creatinine Increased: 3 people, 27.27%
  6. Constipation: 3 people, 27.27%
  7. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 27.27%
  8. Enlarged Prostate: 3 people, 27.27%
  9. High Blood Cholesterol: 3 people, 27.27%
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Plendil and have Spinal column stenosis?

Check whether Spinal column stenosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Spinal column stenosis and when was it recovered:

Expand to all the drugs that have ingredients of felodipine:

Alternative drugs to, pros and cons of Plendil:

Common Plendil side effects:

Browse all side effects of Plendil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Spinal column stenosis treatments and more:

COVID vaccines that are related to Spinal column stenosis:

Common drugs associated with Spinal column stenosis:

All the drugs that are associated with Spinal column stenosis:

Common conditions associated with Spinal column stenosis:

All the conditions that are associated with Spinal column stenosis:

How the study uses the data?

The study uses data from the FDA. It is based on felodipine (the active ingredients of Plendil) and Plendil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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