Prednisolone and Placenta abruptio - a phase IV clinical study of FDA data


Placenta abruptio is found among people who take Prednisolone, especially for people who are 30-39 old.

The phase IV clinical study analyzes which people take Prednisolone and have Placenta abruptio. It is created by eHealthMe based on reports of 180,802 people who have side effects when taking Prednisolone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

180,802 people reported to have side effects when taking Prednisolone.
Among them, 39 people (0.02%) have Placenta abruptio.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 182,045 Prednisolone users for its effectiveness, alternative drugs and more.

What is Placenta abruptio?

Placenta abruptio is found to be associated with 599 drugs and 484 conditions by eHealthMe.

Number of Prednisolone and Placenta abruptio reports submitted per year:

Could Prednisolone cause Placenta abruptio?

Age of people who have Placenta abruptio when taking Prednisolone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 8.33 %
  • 20-29: 33.33 %
  • 30-39: 50.0 %
  • 40-49: 8.33 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Prednisolone *:

  1. Azathioprine: 6 people, 15.38%
  2. Zyrtec: 4 people, 10.26%
  3. Remicade: 4 people, 10.26%
  4. Methylprednisolone: 4 people, 10.26%
  5. Humira: 3 people, 7.69%
  6. Acetylsalicylic Acid: 3 people, 7.69%
  7. Misoprostol: 2 people, 5.13%
  8. Magnesium Sulfate: 2 people, 5.13%
  9. Erythromycin: 2 people, 5.13%
  10. Tracleer: 2 people, 5.13%

Common side effects people have besides Placenta abruptio *:

  1. Maternal Exposure During Pregnancy (use of substance during pregnancy): 16 people, 41.03%
  2. Premature Delivery: 6 people, 15.38%
  3. Foetal Death (death of foetus): 5 people, 12.82%
  4. Hellp Syndrome (life-threatening pregnancy complication): 4 people, 10.26%
  5. Stillbirth (a birth of dead foetus): 4 people, 10.26%
  6. Vaginal Bleeding: 4 people, 10.26%
  7. Premature Labor: 4 people, 10.26%
  8. Premature Baby: 4 people, 10.26%
  9. Complications Of Maternal Exposure To Therapeutic Drugs: 4 people, 10.26%
  10. Motormental Retardation (a slowing-down of thought and a reduction of physical work): 3 people, 7.69%

Common conditions people have *:

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 17.95%
  2. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 5 people, 12.82%
  3. Uveitis (inflammation of the uvea): 4 people, 10.26%
  4. High Blood Pressure: 4 people, 10.26%
  5. Hypertensive Heart Disease: 3 people, 7.69%
  6. Postpartum Haemorrhage (bleeding in woman after she has given birth): 2 people, 5.13%
  7. Maternal Therapy To Enhance Foetal Lung Maturity: 2 people, 5.13%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.13%
  9. Premature Labor: 2 people, 5.13%
  10. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisolone and have Placenta abruptio?

Check whether Placenta abruptio is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Placenta abruptio and when was it recovered:

Expand to all the drugs that have ingredients of prednisolone:

Alternative drugs to, pros and cons of Prednisolone:

Common Prednisolone side effects:

Browse all side effects of Prednisolone:

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Placenta abruptio treatments and more:

COVID vaccines that are related to Placenta abruptio:

Common drugs associated with Placenta abruptio:

All the drugs that are associated with Placenta abruptio:

Common conditions associated with Placenta abruptio:

All the conditions that are associated with Placenta abruptio:

How the study uses the data?

The study uses data from the FDA. It is based on prednisolone (the active ingredients of Prednisolone) and Prednisolone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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