Prednisone and Macular rupture - a phase IV clinical study of FDA data


Macular rupture is reported only by a few people who take Prednisone.

The phase IV clinical study analyzes which people take Prednisone and have Macular rupture. It is created by eHealthMe based on reports of 523,651 people who have side effects while taking Prednisone from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 27, 2023

523,651 people reported to have side effects when taking Prednisone.
Among them, 3 people (0.0%) have Macular rupture.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 531,290 Prednisone users for its effectiveness, alternative drugs and more.

What is Macular rupture?

Macular rupture (breaks in macula a part of internal eye) is found to be associated with 40 drugs and 21 conditions by eHealthMe.

Number of Prednisone and Macular rupture reports submitted per year:

Could Prednisone cause Macular rupture?

Gender of people who have Macular rupture when taking Prednisone *:

  • female: 100 %
  • male: 0.0 %

Common drugs people take besides Prednisone *:

  1. Levaquin: 3 people, 100.00%

Common side effects people have besides Macular rupture *:

  1. Weight Decreased: 3 people, 100.00%
  2. Gait Disturbance: 3 people, 100.00%
  3. Adverse Event: 3 people, 100.00%
  4. Amyotrophic Lateral Sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord): 3 people, 100.00%
  5. Bedridden: 3 people, 100.00%
  6. Bladder Disorder: 3 people, 100.00%
  7. Blindness Unilateral: 3 people, 100.00%
  8. Breathing Difficulty: 3 people, 100.00%
  9. Burning Sensation: 3 people, 100.00%
  10. Cardiac Disorder: 3 people, 100.00%

Common conditions people have *:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Prednisone and have Macular rupture?

Check whether Macular rupture is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Macular rupture and when was it recovered:

Expand to all the drugs that have ingredients of prednisone:

Alternative drugs to, pros and cons of Prednisone:

Common Prednisone side effects:

Browse all side effects of Prednisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Macular rupture treatments and more:

COVID vaccines that are related to Macular rupture:

All the drugs that are associated with Macular rupture:

All the conditions that are associated with Macular rupture:

How the study uses the data?

The study uses data from the FDA. It is based on prednisone (the active ingredients of Prednisone) and Prednisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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