Pregabalin and Tuberculosis - a phase IV clinical study of FDA data


We study 63,777 people who have side effects when taking Pregabalin. Tuberculosis is found, especially among people who are female, 60+ old, also take Humira and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people take Pregabalin and have Tuberculosis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2023

63,777 people reported to have side effects when taking Pregabalin.
Among them, 24 people (0.04%) have Tuberculosis.

What is Pregabalin?

Pregabalin has active ingredients of pregabalin. It is used in fibromyalgia. Currently, eHealthMe is studying from 64,682 Pregabalin users.

What is Tuberculosis?

Tuberculosis (a bacterial infection by mycobacterium tuberculosis) is found to be associated with 1,142 drugs and 751 conditions by eHealthMe. Currently, we are studying 25,049 people who have Tuberculosis.

Number of Pregabalin and Tuberculosis reports submitted per year:

Could Pregabalin cause Tuberculosis?

Gender of people who have Tuberculosis when taking Pregabalin *:

  • female: 76.19 %
  • male: 23.81 %

Age of people who have Tuberculosis when taking Pregabalin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 14.29 %
  • 40-49: 0.0 %
  • 50-59: 35.71 %
  • 60+: 42.86 %

Common drugs people take besides Pregabalin *:

  1. Xeljanz Xr: 4 people, 16.67%
  2. Synthroid: 4 people, 16.67%
  3. Humira: 4 people, 16.67%
  4. Pantoprazole: 3 people, 12.50%
  5. Paracetamol: 3 people, 12.50%
  6. Pyridoxine: 3 people, 12.50%
  7. Methotrexate: 3 people, 12.50%
  8. Vitamin D3: 3 people, 12.50%
  9. Omeprazole: 2 people, 8.33%
  10. Macitentan: 2 people, 8.33%

Common side effects people have besides Tuberculosis *:

  1. Diarrhea: 5 people, 20.83%
  2. Fever: 4 people, 16.67%
  3. Breathing Difficulty: 3 people, 12.50%
  4. Nausea And Vomiting: 3 people, 12.50%
  5. Nausea (feeling of having an urge to vomit): 3 people, 12.50%
  6. Peripheral Swelling: 3 people, 12.50%
  7. Swelling Face: 3 people, 12.50%
  8. Joint Pain: 2 people, 8.33%
  9. Pleuritic Pain: 2 people, 8.33%
  10. Cardiac Tamponade (fluid accumulates in heart covering): 2 people, 8.33%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 41.67%
  2. Pulmonary Tuberculosis (lungs tuberculosis): 3 people, 12.50%
  3. Tumor Necrosis Factor Receptor-Associated Periodic Syndrome: 2 people, 8.33%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 8.33%
  5. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 2 people, 8.33%
  6. Muscle Aches (muscle pain): 2 people, 8.33%
  7. Neuropathy Peripheral (surface nerve damage): 2 people, 8.33%
  8. Pneumonia: 2 people, 8.33%
  9. Renal Osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood): 2 people, 8.33%
  10. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Pregabalin and have Tuberculosis?

Check whether Tuberculosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Pregabalin side effects by duration, gender and age:

Tuberculosis treatments and more:

Common drugs associated with Tuberculosis:

All the drugs that are associated with Tuberculosis:

Common conditions associated with Tuberculosis:

All the conditions that are associated with Tuberculosis:

How the study uses the data?

The study uses data from the FDA. It is based on pregabalin (the active ingredients of Pregabalin) and Pregabalin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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