Who have Skin pale or gray with Premarin - from FDA reports


Skin pale or gray is found among people who take Premarin, especially for people who are female, 60+ old , have been taking the drug for 1 - 6 months, also take medication Synthroid, and have Osteoporosis. This study is created by eHealthMe based on reports of 83,686 people who have side effects when taking Premarin from FDA, and is updated regularly.

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On Feb, 01, 2019

83,686 people reported to have side effects when taking Premarin.
Among them, 110 people (0.13%) have Skin pale or gray


Number of reports submitted per year:

Could Premarin cause Skin pale or gray?

Time on Premarin when people have Skin pale or gray *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Skin pale or gray when taking Premarin *:

  • female: 94.44 %
  • male: 5.56 %

Age of people who have Skin pale or gray when taking Premarin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1 %
  • 20-29: 0.0 %
  • 30-39: 2 %
  • 40-49: 10 %
  • 50-59: 43 %
  • 60+: 44 %

Top conditions involved for these people *:

  1. Osteoporosis (bones weak and more likely to break): 13 people, 11.82%
  2. Depression: 12 people, 10.91%
  3. Sleep Disorder: 11 people, 10.00%
  4. Multiple Allergies (allergy to multiple agents): 10 people, 9.09%
  5. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 8 people, 7.27%
  6. Pain: 7 people, 6.36%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 3.64%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 3.64%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 3.64%
  10. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 4 people, 3.64%

Top co-used drugs for these people *:

  1. Synthroid: 23 people, 20.91%
  2. Lexapro: 22 people, 20.00%
  3. Lasix: 22 people, 20.00%
  4. Xanax: 21 people, 19.09%
  5. Neurontin: 18 people, 16.36%
  6. Prilosec: 17 people, 15.45%
  7. Prevacid: 17 people, 15.45%
  8. Celebrex: 15 people, 13.64%
  9. Toprol-Xl: 14 people, 12.73%
  10. Zofran: 13 people, 11.82%

Top other side effects for these people *:

  1. Nausea (feeling of having an urge to vomit): 41 people, 37.27%
  2. Weakness: 40 people, 36.36%
  3. Dizziness: 38 people, 34.55%
  4. Fatigue (feeling of tiredness): 37 people, 33.64%
  5. Hypotension (abnormally low blood pressure): 33 people, 30.00%
  6. Diarrhea: 28 people, 25.45%
  7. Breathing Difficulty: 25 people, 22.73%
  8. Urinary Tract Infection: 23 people, 20.91%
  9. Headache (pain in head): 23 people, 20.91%
  10. Chest Pain: 21 people, 19.09%

* Approximation only. Some reports may have incomplete information.

Do you have Skin pale or gray while taking Premarin?


You are not alone:




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Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. (latest outcomes from Premarin 84,639 users)

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Premarin side effects

Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Browse all side effects of Premarin
a b c d e f g h i j k l m n o p q r s t u v w x y z

Compare Premarin to similar drugs:


What would happen?

Predict new side effects and undetected conditions when you take Premarin and have Skin pale or gray


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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