Premarin and Tinnitus - from FDA reports

Tinnitus is found among people who take Premarin, especially for people who are female, 60+ old , have been taking the drug for 10+ years, also take medication Synthroid, and have Depression. This review analyzes which people have Tinnitus with Premarin. It is created by eHealthMe based on reports of 80,594 people who have side effects when taking Premarin from FDA , and is updated regularly.


On Jun, 08, 2018

80,594 people reported to have side effects when taking Premarin.
Among them, 414 people (0.51%) have Tinnitus

Number of reports submitted per year:

Could Premarin cause Tinnitus?

Time on Premarin when people have Tinnitus *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 9.52 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 28.57 %
  • 10+ years: 61.9 %

Gender of people who have Tinnitus when taking Premarin *:

  • female: 98.76 %
  • male: 1.24 %

Age of people who have Tinnitus when taking Premarin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.29 %
  • 20-29: 0.59 %
  • 30-39: 2.95 %
  • 40-49: 12.39 %
  • 50-59: 38.05 %
  • 60+: 45.72 %

Top conditions involved for these people *:

  1. Depression: 42 people, 10.14%
  2. Osteoporosis (bones weak and more likely to break): 35 people, 8.45%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 20 people, 4.83%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 4.11%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 16 people, 3.86%
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Top co-used drugs for these people *:

  1. Synthroid: 82 people, 19.81%
  2. Vioxx: 74 people, 17.87%
  3. Fosamax: 74 people, 17.87%
  4. Lipitor: 62 people, 14.98%
  5. Celebrex: 59 people, 14.25%
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Top other side effects for these people *:

  1. Dizziness: 128 people, 30.92%
  2. Headache (pain in head): 114 people, 27.54%
  3. Pain: 101 people, 24.40%
  4. Fall: 98 people, 23.67%
  5. Fatigue (feeling of tiredness): 98 people, 23.67%
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* Approximation only. Some reports may have incomplete information.

What's next:

Do you take Premarin and have Tinnitus?

Related studies


Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. (latest outcomes from Premarin 81,546 users)


Tinnitus (a ringing in the ears) has been reported by people with depression, high blood pressure, pain, osteoporosis, high blood cholesterol (latest reports from 31,649 Tinnitus patients).

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What would happen?

Predict new side effects and undetected conditions when you take Premarin and have Tinnitus

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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