Premphase and Gastroesophageal reflux disease - a phase IV clinical study of FDA data

Summary:

Gastroesophageal reflux disease is found among people who take Premphase, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Premphase and have Gastroesophageal reflux disease. It is created by eHealthMe based on reports of 2,243 people who have side effects when taking Premphase from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 03, 2023

2,243 people reported to have side effects when taking Premphase.
Among them, 25 people (1.11%) have Gastroesophageal reflux disease.

What is Premphase?

Premphase has active ingredients of estrogens, conjugated; medroxyprogesterone acetate. eHealthMe is studying from 2,242 Premphase users for its effectiveness, alternative drugs and more.

What is Gastroesophageal reflux disease?

Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus) is found to be associated with 3,780 drugs and 3,366 conditions by eHealthMe.

Number of Premphase and Gastroesophageal reflux disease reports submitted per year:

Could Premphase cause Gastroesophageal reflux disease?

Gender of people who have Gastroesophageal reflux disease when taking Premphase *:

female: 100 %
male: 0.0 %

Age of people who have Gastroesophageal reflux disease when taking Premphase *:

Common drugs people take besides Premphase *:

Common side effects people have besides Gastroesophageal reflux disease *:

Back Pain: 22 people, 88.00%
Nausea (feeling of having an urge to vomit): 21 people, 84.00%
Stress And Anxiety: 21 people, 84.00%
Pneumonia: 21 people, 84.00%
Renal Failure Acute (rapid kidney dysfunction): 21 people, 84.00%
Chest Pain: 21 people, 84.00%
Dizziness: 20 people, 80.00%
Nausea And Vomiting: 20 people, 80.00%
Osteomyelitis (infection of bone): 20 people, 80.00%
Dental Caries: 20 people, 80.00%

Common conditions people have *:

Stress And Anxiety: 13 people, 52.00%
Pain In Jaw: 13 people, 52.00%
Multiple Myeloma (cancer of the plasma cells): 13 people, 52.00%
Metastases To Bone (cancer spreads to bone): 7 people, 28.00%
Osteoporosis (bones weak and more likely to break): 2 people, 8.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 8.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.00%
Postmenopause: 1 person, 4.00%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 4.00%
Migraine (headache): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Premphase and have Gastroesophageal reflux disease?

Check whether Gastroesophageal reflux disease is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Gastroesophageal reflux disease and when was it recovered:

Gastroesophageal reflux disease in Premphase

Expand to all the drugs that have ingredients of estrogens, conjugated; medroxyprogesterone acetate:

Gastroesophageal reflux disease and drugs with ingredients of estrogens, conjugated; medroxyprogesterone acetate (368 reports)

Alternative drugs to, pros and cons of Premphase:

Premphase (2,242 reports)

Common Premphase side effects:

Breast cancer: 675 reports

Browse all side effects of Premphase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Gastroesophageal reflux disease treatments and more:

Gastroesophageal reflux disease (400,246 reports)

COVID vaccines that are related to Gastroesophageal reflux disease:

Common drugs associated with Gastroesophageal reflux disease:

All the drugs that are associated with Gastroesophageal reflux disease:

Gastroesophageal reflux disease (3,780 drugs)

Common conditions associated with Gastroesophageal reflux disease:

High blood pressure: 8,283 reports
Osteoporosis: 6,304 reports
Pain: 4,963 reports

All the conditions that are associated with Gastroesophageal reflux disease:

Gastroesophageal reflux disease (3,366 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estrogens, conjugated; medroxyprogesterone acetate (the active ingredients of Premphase) and Premphase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.