Prilosec and Tumor lysis syndrome - a phase IV clinical study of FDA data
We study 169,596 people who have side effects when taking Prilosec. Tumor lysis syndrome is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take Acetaminophen and have Chronic lymphocytic leukaemia.
The phase IV clinical study analyzes which people take Prilosec and have Tumor lysis syndrome. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
169,596 people reported to have side effects when taking Prilosec.
Among them, 38 people (0.02%) have Tumor lysis syndrome.
What is Prilosec?
Prilosec has active ingredients of omeprazole. It is used in gastroesophageal reflux disease. Currently, eHealthMe is studying from 173,263 Prilosec users.
What is Tumor lysis syndrome?
Tumor lysis syndrome is found to be associated with 1,104 drugs and 742 conditions by eHealthMe. Currently, we are studying 11,438 people who have Tumor lysis syndrome.
Number of Prilosec and Tumor lysis syndrome reports submitted per year:
Time on Prilosec when people have Tumor lysis syndrome *:
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Tumor lysis syndrome when taking Prilosec *:
- female: 18.92 %
- male: 81.08 %
Age of people who have Tumor lysis syndrome when taking Prilosec *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 2.86 %
- 40-49: 2.86 %
- 50-59: 11.43 %
- 60+: 82.86 %
Common drugs people take besides Prilosec *:
- Acetaminophen: 12 people, 31.58%
- Aspirin: 11 people, 28.95%
- Benadryl: 11 people, 28.95%
- Norvasc: 11 people, 28.95%
- Calcium Acetate: 9 people, 23.68%
- Lasix: 9 people, 23.68%
- Ambien: 8 people, 21.05%
- Allopurinol: 8 people, 21.05%
- Pravastatin Sodium: 8 people, 21.05%
- Hydrochlorothiazide: 8 people, 21.05%
Common side effects people have besides Tumor lysis syndrome *:
- Renal Failure Acute (rapid kidney dysfunction): 12 people, 31.58%
- Sepsis (a severe blood infection that can lead to organ failure and death): 9 people, 23.68%
- Cardiac Arrest: 7 people, 18.42%
- Anaemia (lack of blood): 7 people, 18.42%
- Hyperkalemia (damage to or disease of the kidney): 7 people, 18.42%
- Thrombocytopenia (decrease of platelets in blood): 7 people, 18.42%
- Hyperglycemia (high blood sugar): 6 people, 15.79%
- Leukopenia (less number of white blood cells in blood): 5 people, 13.16%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 10.53%
- Oedema Peripheral (superficial swelling): 3 people, 7.89%
Common conditions people have *:
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 12 people, 31.58%
- Oral Cancer (mouth cancer): 8 people, 21.05%
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 7 people, 18.42%
- Stress And Anxiety: 3 people, 7.89%
- Pain: 3 people, 7.89%
- Depression: 3 people, 7.89%
- Nausea (feeling of having an urge to vomit): 2 people, 5.26%
- Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 5.26%
- Lymphoma (cancer that begins in immune system cells): 2 people, 5.26%
- Dizziness: 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Prilosec and have Tumor lysis syndrome?Check whether Tumor lysis syndrome is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Prilosec side effects by duration, gender and age:
- Prilosec side effects (173,263 reports)
Tumor lysis syndrome treatments and more:
- Tumor lysis syndrome (11,438 reports)
Common drugs associated with Tumor lysis syndrome:
- Cyclophosphamide: 1,281 reports
- Allopurinol: 1,133 reports
- Lopurin: 1,133 reports
- Prednisone: 884 reports
- Etoposide: 718 reports
- Dexamethasone: 587 reports
- Cytarabine: 573 reports
- Prednisolone: 523 reports
- Methotrexate: 479 reports
- Velcade: 476 reports
All the drugs that are associated with Tumor lysis syndrome:
- Tumor lysis syndrome (1,104 drugs)
Common conditions associated with Tumor lysis syndrome:
- Multiple myeloma: 1,051 reports
- Non-hodgkin's lymphoma: 516 reports
- High blood pressure: 374 reports
- Preventive health care: 298 reports
- Acute lymphocytic leukemia (all): 244 reports
- Pain: 233 reports
All the conditions that are associated with Tumor lysis syndrome:
- Tumor lysis syndrome (742 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on omeprazole (the active ingredients of Prilosec) and Prilosec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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