Profen and Drug ineffective - a phase IV clinical study of FDA data
Summary:
We study 204,671 people who have side effects when taking Profen. Drug ineffective is found, especially among people who are female, 40-49 old, have been taking the drug for < 1 month, also take Enbrel and have Rheumatoid arthritis.
The phase IV clinical study analyzes which people take Profen and have Drug ineffective. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
204,671 people reported to have side effects when taking Profen.
Among them, 14,999 people (7.33%) have Drug ineffective.
What is Profen?
Profen has active ingredients of ibuprofen. It is used in pain. Currently, eHealthMe is studying from 231,301 Profen users.
What is Drug ineffective?
Drug ineffective is found to be associated with 4,594 drugs and 5,069 conditions by eHealthMe. Currently, we are studying 1,271,526 people who have Drug ineffective.
Number of Profen and Drug ineffective reports submitted per year:

Time on Profen when people have Drug ineffective *:
Gender of people who have Drug ineffective when taking Profen*:
Age of people who have Drug ineffective when taking Profen *:
Common drugs people take besides Profen *:
Common side effects people have besides Drug ineffective *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Profen and have Drug ineffective?
Check whether Drug ineffective is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Related studies
Profen side effects by duration, gender and age:
- Profen side effects (231,301 reports)
Drug ineffective treatments and more:
- Drug ineffective (1,271,526 reports)
Common drugs associated with Drug ineffective:
- Methotrexate: 115,658 reports
- Humira: 103,759 reports
- Enbrel: 90,931 reports
- Prednisone: 66,683 reports
- Xeljanz: 48,562 reports
- Orencia: 47,976 reports
- Adapalene: 45,683 reports
- Actemra: 44,969 reports
- Remicade: 37,128 reports
- Sulfasalazine: 35,158 reports
All the drugs that are associated with Drug ineffective:
- Drug ineffective (4,594 drugs)
Common conditions associated with Drug ineffective:
- Rheumatoid arthritis: 123,880 reports
- Pain: 40,150 reports
- Psoriasis: 33,532 reports
- High blood pressure: 31,954 reports
- Multiple sclerosis: 25,819 reports
- Depression: 24,053 reports
All the conditions that are associated with Drug ineffective:
- Drug ineffective (5,069 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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