Profen and Intervertebral disc protrusion - a phase IV clinical study of FDA data

Summary:

Intervertebral disc protrusion is found among people who take Profen, especially for people who are female, 50-59 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Profen and have Intervertebral disc protrusion. It is created by eHealthMe based on reports of 225,403 people who have side effects when taking Profen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

225,403 people reported to have side effects when taking Profen.
Among them, 1,121 people (0.5%) have Intervertebral disc protrusion.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 231,301 Profen users for its effectiveness, alternative drugs and more.

What is Intervertebral disc protrusion?

Intervertebral disc protrusion (spinal disc protrusion) is found to be associated with 2,236 drugs and 1,261 conditions by eHealthMe.

Number of Profen and Intervertebral disc protrusion reports submitted per year:

Could Profen cause Intervertebral disc protrusion?

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Intervertebral disc protrusion?

Check whether Intervertebral disc protrusion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

Related studies

How severe was Intervertebral disc protrusion and when was it recovered:

Intervertebral disc protrusion in Profen

Expand to all the drugs that have ingredients of ibuprofen:

Intervertebral disc protrusion and drugs with ingredients of ibuprofen (943 reports)

Alternative drugs to, pros and cons of Profen:

Profen (231,301 reports)

Common Profen side effects:

Pain: 17,497 reports
Fatigue (feeling of tiredness): 15,338 reports
Drug ineffective: 14,999 reports
Headache (pain in head): 13,179 reports
Nausea and vomiting: 11,560 reports
Rashes (redness): 11,357 reports
Breathing difficulty: 10,787 reports

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Intervertebral disc protrusion treatments and more:

Intervertebral disc protrusion (32,035 reports)

COVID vaccines that are related to Intervertebral disc protrusion:

Common drugs associated with Intervertebral disc protrusion:

All the drugs that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (2,236 drugs)

Common conditions associated with Intervertebral disc protrusion:

All the conditions that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (1,261 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.