Profen and Stomach discomfort - a phase IV clinical study of FDA data

Summary:

Stomach discomfort is found among people who take Profen, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Profen and have Stomach discomfort. It is created by eHealthMe based on reports of 204,671 people who have side effects when taking Profen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 22, 2023

204,671 people reported to have side effects when taking Profen.
Among them, 72 people (0.04%) have Stomach discomfort.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,513 Profen users for its effectiveness, alternative drugs and more.

What is Stomach discomfort?

Stomach discomfort (pain in abdomen) is found to be associated with 1,049 drugs and 734 conditions by eHealthMe.

Number of Profen and Stomach discomfort reports submitted per year:

Time on Profen when people have Stomach discomfort *:

Gender of people who have Stomach discomfort when taking Profen *:

female: 56.94 %
male: 43.06 %

Age of people who have Stomach discomfort when taking Profen *:

Common drugs people take besides Profen *:

Common side effects people have besides Stomach discomfort *:

Nausea (feeling of having an urge to vomit): 24 people, 33.33%
Headache (pain in head): 14 people, 19.44%
Drug Ineffective: 12 people, 16.67%
Dizziness: 10 people, 13.89%
Fall: 8 people, 11.11%
Fatigue (feeling of tiredness): 7 people, 9.72%
Memory Loss: 7 people, 9.72%
Muscle Aches (muscle pain): 7 people, 9.72%
Chest Pain: 6 people, 8.33%
High Blood Cholesterol: 6 people, 8.33%

Common conditions people have *:

Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 11.11%
Ill-Defined Disorder: 5 people, 6.94%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.94%
Quit Smoking: 5 people, 6.94%
High Blood Cholesterol: 5 people, 6.94%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 6.94%
Migraine (headache): 4 people, 5.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.56%
Diabetes: 4 people, 5.56%
Fungal Nail Infection: 3 people, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Profen and have Stomach discomfort?

Check whether Stomach discomfort is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

Related studies

How severe was Stomach discomfort and when was it recovered:

Stomach discomfort in Profen

Expand to all the drugs that have ingredients of ibuprofen:

Stomach discomfort and drugs with ingredients of ibuprofen

Alternative drugs to, pros and cons of Profen:

Profen (210,513 reports)

Common Profen side effects:

Pain: 17,497 reports
Fatigue (feeling of tiredness): 15,338 reports
Drug ineffective: 14,999 reports
Headache (pain in head): 13,179 reports
Rashes (redness): 11,409 reports
Breathing difficulty: 10,787 reports
Joint pain: 10,715 reports
Nausea and vomiting: 10,620 reports

Browse all side effects of Profen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Stomach discomfort treatments and more:

Stomach discomfort (7,988 reports)

COVID vaccines that are related to Stomach discomfort:

Common drugs associated with Stomach discomfort:

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Profen) and Profen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.