Prograf and Protein urine - a phase IV clinical study of FDA data


Protein urine is found among people who take Prograf, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Prograf and have Protein urine. It is created by eHealthMe based on reports of 39,863 people who have side effects when taking Prograf from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2022

39,863 people reported to have side effects when taking Prograf.
Among them, 12 people (0.03%) have Protein urine.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 40,358 Prograf users for its effectiveness, alternative drugs and more.

What is Protein urine?

Protein urine is found to be associated with 886 drugs and 496 conditions by eHealthMe.

Number of Prograf and Protein urine reports submitted per year:

Could Prograf cause Protein urine?

Gender of people who have Protein urine when taking Prograf *:

  • female: 75 %
  • male: 25 %

Age of people who have Protein urine when taking Prograf *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 18.18 %
  • 30-39: 9.09 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 72.73 %

Common drugs people take besides Prograf *:

  1. Cellcept: 4 people, 33.33%
  2. Vesicare: 3 people, 25.00%
  3. Aromasin: 3 people, 25.00%
  4. Norvasc: 3 people, 25.00%
  5. Zopiclone: 2 people, 16.67%
  6. Olmetec: 2 people, 16.67%
  7. Adcirca: 2 people, 16.67%
  8. Ambrisentan: 2 people, 16.67%
  9. Aricept: 2 people, 16.67%
  10. Forteo: 2 people, 16.67%

Common side effects people have besides Protein urine *:

  1. Stomatitis (inflammation of mucous membrane of mouth): 3 people, 25.00%
  2. Renal Cell Carcinoma (a kidney cancer): 3 people, 25.00%
  3. Anal Haemorrhage: 2 people, 16.67%
  4. Back Pain: 2 people, 16.67%
  5. Eczema Asteatotic (severe dry skin- during the winter months and in the elderly): 2 people, 16.67%
  6. Blood Urine Present: 2 people, 16.67%
  7. Metastases To Liver (cancer spreads to liver): 2 people, 16.67%
  8. Metastases To Lung (cancer spreads to lung): 2 people, 16.67%
  9. Oedema Peripheral (superficial swelling): 2 people, 16.67%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%

Common conditions people have *:

  1. Lymphangioleiomyomatosis (a rare lung condition that affects a certain type of muscle cell and only occurs in women): 3 people, 25.00%
  2. Immunodeficiency Disorders: 3 people, 25.00%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 16.67%
  4. Diabetes: 2 people, 16.67%
  5. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 8.33%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
  7. Pain: 1 person, 8.33%
  8. Insomnia (sleeplessness): 1 person, 8.33%
  9. High Blood Pressure: 1 person, 8.33%
  10. Gestational Hypertension (elevated blood pressure during pregnancy): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and have Protein urine?

Check whether Protein urine is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Protein urine and when was it recovered:

Expand to all the drugs that have ingredients of tacrolimus:

Alternative drugs to, pros and cons of Prograf:

Common Prograf side effects:

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Protein urine treatments and more:

COVID vaccines that are related to Protein urine:

Common drugs associated with Protein urine:

All the drugs that are associated with Protein urine:

All the conditions that are associated with Protein urine:

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus (the active ingredients of Prograf) and Prograf (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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