Propafenone hydrochloride and Nephrotic syndrome - a phase IV clinical study of FDA data


Nephrotic syndrome is reported only by a few people who take Propafenone Hydrochloride.

The phase IV clinical study analyzes which people take Propafenone hydrochloride and have Nephrotic syndrome. It is created by eHealthMe based on reports of 1,096 people who have side effects while taking Propafenone hydrochloride from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 28, 2022

1,096 people reported to have side effects when taking Propafenone hydrochloride.
Among them, 2 people (0.18%) have Nephrotic syndrome.

What is Propafenone hydrochloride?

Propafenone hydrochloride has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 1,278 Propafenone hydrochloride users for its effectiveness, alternative drugs and more.

What is Nephrotic syndrome?

Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema) is found to be associated with 1,361 drugs and 973 conditions by eHealthMe.

Number of Propafenone hydrochloride and Nephrotic syndrome reports submitted per year:

Could Propafenone hydrochloride cause Nephrotic syndrome?

Time on Propafenone hydrochloride when people have Nephrotic syndrome *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Nephrotic syndrome when taking Propafenone hydrochloride *:

  • female: 0.0 %
  • male: 100 %

Age of people who have Nephrotic syndrome when taking Propafenone hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Propafenone hydrochloride *:

  1. Tizanidine Hydrochloride: 2 people, 100.00%
  2. Tacrolimus: 2 people, 100.00%
  3. Pregabalin: 2 people, 100.00%
  4. Omeprazole: 2 people, 100.00%
  5. Humira: 2 people, 100.00%
  6. Epinastine Hydrochloride: 2 people, 100.00%
  7. Diclofenac Sodium: 2 people, 100.00%
  8. Verapamil Hydrochloride: 1 person, 50.00%
  9. Verapamil Hcl: 1 person, 50.00%

Common side effects people have besides Nephrotic syndrome *:

  1. Pleural Effusion (water on the lungs): 1 person, 50.00%
  2. Brain Natriuretic Peptide Abnormal: 1 person, 50.00%

Common conditions people have *:

  1. Spinal Osteoarthritis (joint cartilage loss in spine): 2 people, 100.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 100.00%
  3. Muscle Spasms (muscle contraction): 2 people, 100.00%
  4. Insomnia (sleeplessness): 2 people, 100.00%
  5. Allergies: 2 people, 100.00%
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 1 person, 50.00%
  7. Lumbar Spinal Stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 1 person, 50.00%
  8. Cervicobrachial Syndrome (pain in neck and arm with changing location): 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Propafenone hydrochloride and have Nephrotic syndrome?

Check whether Nephrotic syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Nephrotic syndrome and when was it recovered:

Expand to all the drugs that have ingredients of propafenone hydrochloride:

Alternative drugs to, pros and cons of Propafenone hydrochloride:

Common Propafenone hydrochloride side effects:

Browse all side effects of Propafenone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Nephrotic syndrome treatments and more:

COVID vaccines that are related to Nephrotic syndrome:

Common drugs associated with Nephrotic syndrome:

All the drugs that are associated with Nephrotic syndrome:

Common conditions associated with Nephrotic syndrome:

All the conditions that are associated with Nephrotic syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on propafenone hydrochloride (the active ingredients of Propafenone hydrochloride) and Propafenone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: