Propofol and Hepatic congestion - a phase IV clinical study of FDA data


Hepatic congestion is found among people who take Propofol, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Propofol and have Hepatic congestion. It is created by eHealthMe based on reports of 32,167 people who have side effects when taking Propofol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 06, 2022

32,167 people reported to have side effects when taking Propofol.
Among them, 37 people (0.12%) have Hepatic congestion.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 32,371 Propofol users for its effectiveness, alternative drugs and more.

What is Hepatic congestion?

Hepatic congestion (liver congestion) is found to be associated with 863 drugs and 425 conditions by eHealthMe.

Number of Propofol and Hepatic congestion reports submitted per year:

Could Propofol cause Hepatic congestion?

Time on Propofol when people have Hepatic congestion *:

  • < 1 month: 77.78 %
  • 1 - 6 months: 22.22 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hepatic congestion when taking Propofol *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Hepatic congestion when taking Propofol *:

  • 0-1: 15.62 %
  • 2-9: 3.12 %
  • 10-19: 3.12 %
  • 20-29: 0.0 %
  • 30-39: 18.75 %
  • 40-49: 3.12 %
  • 50-59: 0.0 %
  • 60+: 56.25 %

Common drugs people take besides Propofol *:

  1. Fentanyl: 14 people, 37.84%
  2. Lansoprazole: 12 people, 32.43%
  3. Lisinopril: 12 people, 32.43%
  4. Atorvastatin Calcium: 12 people, 32.43%
  5. Quinine Sulfate: 11 people, 29.73%
  6. Budesonide: 10 people, 27.03%
  7. Arava: 9 people, 24.32%
  8. Aspirin: 9 people, 24.32%
  9. Pancuronium: 7 people, 18.92%
  10. Nitroglycerin: 7 people, 18.92%

Common side effects people have besides Hepatic congestion *:

  1. Acute Kidney Failure: 18 people, 48.65%
  2. Hypovolaemia (a decreased volume of circulating blood in the body): 18 people, 48.65%
  3. Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 14 people, 37.84%
  4. Post Procedural Haemorrhage (post procedural bleeding): 13 people, 35.14%
  5. Labile Blood Pressure (wildly fluctuating blood pressure): 12 people, 32.43%
  6. Thrombocytopenia (decrease of platelets in blood): 12 people, 32.43%
  7. Haematemesis (vomiting of blood): 11 people, 29.73%
  8. High Blood Pressure: 11 people, 29.73%
  9. Gastric Ulcer (stomach ulcer): 11 people, 29.73%
  10. Hepatorenal Syndrome (renal failure in patients with advanced chronic liver disease): 10 people, 27.03%

Common conditions people have *:

  1. High Blood Pressure: 18 people, 48.65%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 24.32%
  3. Anaesthesia: 8 people, 21.62%
  4. High Blood Cholesterol: 8 people, 21.62%
  5. Gastric Ulcer (stomach ulcer): 7 people, 18.92%
  6. Muscle Spasms (muscle contraction): 7 people, 18.92%
  7. Asthma: 7 people, 18.92%
  8. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 7 people, 18.92%
  9. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 5 people, 13.51%
  10. Escherichia Test Positive: 5 people, 13.51%

* Approximation only. Some reports may have incomplete information.

Do you take Propofol and have Hepatic congestion?

Check whether Hepatic congestion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

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Hepatic congestion treatments and more:

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Common drugs associated with Hepatic congestion:

All the drugs that are associated with Hepatic congestion:

Common conditions associated with Hepatic congestion:

All the conditions that are associated with Hepatic congestion:

How the study uses the data?

The study uses data from the FDA. It is based on propofol (the active ingredients of Propofol) and Propofol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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