Protonix and Barrett's oesophagus - a phase IV clinical study of FDA data

Summary:

We study 124,840 people who have side effects when taking Protonix. Barrett's oesophagus is found, especially among people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take Aspirin and have High blood pressure.

The phase IV clinical study analyzes which people take Protonix and have Barrett's oesophagus. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 22, 2023

124,840 people reported to have side effects when taking Protonix.
Among them, 255 people (0.2%) have Barrett's oesophagus.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is used in gastroesophageal reflux disease. Currently, eHealthMe is studying from 130,835 Protonix users.

What is Barrett's oesophagus?

Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach) is found to be associated with 1,204 drugs and 595 conditions by eHealthMe. Currently, we are studying 7,994 people who have Barrett's oesophagus.

Number of Protonix and Barrett's oesophagus reports submitted per year:

Could Protonix cause Barrett's oesophagus?

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and have Barrett's oesophagus?

Check whether Barrett's oesophagus is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Protonix side effects by duration, gender and age:

Protonix side effects (130,835 reports)

Barrett's oesophagus treatments and more:

Barrett's oesophagus (7,994 reports)

Common drugs associated with Barrett's oesophagus:

All the drugs that are associated with Barrett's oesophagus:

Barrett's oesophagus (1,204 drugs)

Common conditions associated with Barrett's oesophagus:

Gastroesophageal reflux disease: 559 reports
High blood pressure: 446 reports
Osteoporosis: 348 reports
High blood cholesterol: 251 reports
Rheumatoid arthritis: 180 reports

All the conditions that are associated with Barrett's oesophagus:

Barrett's oesophagus (595 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium (the active ingredients of Protonix) and Protonix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.