Pylera and Purpura - a phase IV clinical study of FDA data


Purpura is reported only by a few people who take Pylera.

The phase IV clinical study analyzes which people take Pylera and have Purpura. It is created by eHealthMe based on reports of 775 people who have side effects while taking Pylera from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

775 people reported to have side effects when taking Pylera.
Among them, 3 people (0.39%) have Purpura.

What is Pylera?

Pylera has active ingredients of bismuth subcitrate potassium; metronidazole; tetracycline. eHealthMe is studying from 796 Pylera users for its effectiveness, alternative drugs and more.

What is Purpura?

Purpura (purplish discoloration of the skin) is found to be associated with 1,680 drugs and 1,319 conditions by eHealthMe.

Number of Pylera and Purpura reports submitted per year:

Could Pylera cause Purpura?

Time on Pylera when people have Purpura *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Purpura when taking Pylera *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Purpura when taking Pylera *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Pylera *:

  1. Pantoprazole: 3 people, 100.00%
  2. Micardis: 3 people, 100.00%

Common side effects people have besides Purpura *:

  1. Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 3 people, 100.00%
  2. Eosinophilia (eosinophil count in the peripheral blood exceeds): 3 people, 100.00%

Common conditions people have *:

  1. High Blood Pressure: 3 people, 100.00%
  2. High Blood Cholesterol: 3 people, 100.00%
  3. Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 3 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pylera and have Purpura?

Check whether Purpura is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Pylera:

Purpura treatments and more:

COVID vaccines that are related to Purpura:

How severe was Purpura and when was it recovered:

Expand to all the drugs that have ingredients of bismuth subcitrate potassium; metronidazole; tetracycline:

Common drugs associated with Purpura:

All the drugs that are associated with Purpura:

Common conditions associated with Purpura:

All the conditions that are associated with Purpura:

How the study uses the data?

The study uses data from the FDA. It is based on bismuth subcitrate potassium; metronidazole; tetracycline (the active ingredients of Pylera) and Pylera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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